A clinical trial comparing pantoprazole and esomeprazole to explore the concept of achieving 'complete remission' in gastro-oesophageal reflux disease

Alimentary Pharmacology and Therapeutics

Volumn 25, Issue 12, 2007, Pages 1461-1469

  Bardhan, K D ^a   Achim, A ^b   Riddermann, T ^b   Pfaffenberger, B ^b  

^a ROTHERHAM GENERAL HOSPITAL   (United Kingdom)

^b District General Hospital ^*  (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ESOMEPRAZOLE; PANTOPRAZOLE;

ADULT; ARTICLE; BRONCHITIS; CHOLECYSTITIS; CLINICAL TRIAL; COLON CANCER; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; FEMALE; GASTROENTERITIS; GASTROESOPHAGEAL REFLUX; GASTROINTESTINAL ENDOSCOPY; HEADACHE; HEALING; HUMAN; KIDNEY CARCINOMA; KNEE MENISECTOMY; MAJOR CLINICAL STUDY; MALE; MENISCECTOMY; MULTICENTER STUDY; NERVE PARALYSIS; PNEUMONIA; POSTOPERATIVE THROMBOSIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; REMISSION; RHINOPHARYNGITIS; SIDE EFFECT; SYMPTOM; URINE INCONTINENCE;

EID: 34249802897     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2007.03337.x     Document Type: Article

References (16)

1. Locke GR, Zinsmeister AR, Talley NJ. Can symptoms predict endoscopic findings in GERD? Gastrointest Endosc 2003 8 : 61 70.
2. Dent J, Brun J, Fendrick AM, et al. on behalf of the Genval Workshop Group. An evidence-based appraisal of reflux disease management - the Genval Workshop Report. Gut 1999 44 : S1 16.
3. Stanghellini V, Cogliandro R, Cogliandro L, De Giorgio R, Barbara G, Corinaldesi R. Unsolved problems in the management of patients with gastro-oesophageal reflux disease. Dig Liver Dis 2003 35 : 843 8.
4. Okamoto K, Iwakiri R, Mori M, et al. Clinical symptoms in endoscopic reflux esophagitis: evaluation in 8031 adult subjects. Dig Dis Sci 2003 48 : 2237 41.
5. Lundell LR, Dent J, Bennett JR, et al. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification. Gut 1999 45 : 172 80.
6. Shaker R, Castell DO, Schoenfeld PS, Spechler SJ. Nighttime heartburn is an under-appreciated clinical problem that impacts sleep and daytime function: the results of a Gallup survey conducted on behalf of the American Gastroenterological Association. Am J Gastroenterol 2003 98 : 1487 93.
7. Bardhan KD, Stanghellini V, Armstrong D, Berghofer P, Gatz G, Monnikes H. Evaluation of GERD symptoms during therapy Part I. Development of the new GERD questionnaire ReQuest. Digestion 2004 69 : 229 37.
8. Monnikes H, Bardhan KD, Stanghellini V, Berghofer P, Bethke TD, Armstrong D. Evaluation of GERD symptoms during therapy Part II. Psychometric evaluation and validation of the new questionnaire ReQuest in erosive GERD. Digestion 2004 69 : 238 44.
9. Bardhan KD, Stanghellini V, Armstrong D, Berghofer P, Gatz G, Monnikes H. International validation of ReQuest in patients with endoscopy-negative gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2004 20 : 891 8.
10. Stanghellini V, Armstrong D, Monnikes H, Berghofer P, Gatz G, Bardhan KD. Determination of ReQuest-based symptom thresholds to define symptom relief in GERD clinical studies. Digestion 2005 71 : 145 51.
11. Elashoff JD. nQuery Advisor® Version 4.0. User's Guide. Los Angeles, CA : 2000.
12. Newcombe RG. Interval estimation for the difference between independent proportions: comparison of eleven methods. Stat Med 1998 17 : 873 90.
13. Zeitoun P, Rampal R, Barbier P, Isal JP, Eriksson S, Carlsson R. Omeprazole (20 mg daily) compared to ranitidine (150 mg twice daily) in the treatment of esophagitis caused by reflux results of a double-blind randomized multicenter trial in France and Belgium. Gastroenterol Clin Biol 1989 13 : 457 62.
14. Bate CM, Keeling PW, O'Morain C, et al. Comparison of omeprazole and cimetidine in reflux oesophagitis: symptomatic, endoscopic, and histological evaluations. Gut 1990 31 : 968 72.
15. Bate CM, Crowe J, Dickinson RJ. Omeprazole 20 mg o.m. vs. ranitidine 150 mg b.d. in reflux oesophagitis: omeprazole 40 mg o.m - a strategy fortreatment failures. Gut 1990 31 : A1190.
16. Monnikes H. The complete remission concept. Drugs Today (Barc) 2006 42 : 9 14.