The results of surgical excision and adjuvant irradiation for therapy-resistant keloids: A prospective clinical outcome study

Plastic and Reconstructive Surgery

Volumn 119, Issue 7, 2007, Pages 2248-2254

  Van De Kar, Annekatrien L ^b   Kreulen, Mick ^a   Van Zuijlen, Paul P M ^b   Oldenburger, Foppe ^b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FOLLOW UP; HISTOLOGY; HUMAN; HUMAN TISSUE; KELOID; MALE; OUTCOME ASSESSMENT; POSTOPERATIVE CARE; PRIORITY JOURNAL; RECURRENT DISEASE; SURGICAL TECHNIQUE; ADJUVANT THERAPY; ADOLESCENT; CLINICAL TRIAL; MIDDLE AGED; PROSPECTIVE STUDY; REVIEW; TREATMENT OUTCOME;

ADOLESCENT; ADULT; FEMALE; FOLLOW-UP STUDIES; HUMANS; KELOID; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; RECURRENCE; TREATMENT OUTCOME;

EID: 34249788721     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.prs.0000260751.20217.28     Document Type: Article

References (28)

1. Muir, I. F. On the nature of keloid and hypertrophic scars. Br. J. Plast. Surg. 43: 61, 1990.
2. Ogawa, R., Mitsuhashi, K., Hyakusoku, H., and Miyashita, T. Postoperative electron-beam irradiation therapy for keloids and hypertrophic scars: Retrospective study of 147 cases followed for more than 18 months. Plast. Reconstr. Surg. 111: 547, 2003.
3. Urioste, S. S., Arndt, K. A., and Dover, J. S. Keloids and hypertrophic scars: Review and treatment strategies. Semin. Cutan. Med. Surg. 18: 159, 1999.
4. Ship, A. G., Weiss, P. R., Mincer, F. R., and Wolkstein, W. Sternal keloids: Successful treatment employing surgery and adjunctive radiation. Ann. Plast. Surg. 31: 481, 1993.
5. Levy, D. S., Salter, M. M., and Roth, R. E. Postoperative irradiation in the prevention of keloids. A.J.R. Am. J. Roentgenol. 127: 509, 1976.
6. Inalsingh, C. H. An experience in treating five hundred and one patients with keloids. Johns Hopkins Med. J. 134: 284, 1974.
7. Ashbell, T. S. Prevention and treatment of earlobe keloids. Ann. Plast. Surg. 9: 264, 1982.
8. Hintz, B. L. Radiotherapy for keloid treatment. J. Natl. Med. Assoc. 65: 71, 1973.
9. Craig, R. D., and Pearson, D. Early post-operative irradiation in the treatment of keloid scars. Br. J. Plast. Surg. 18: 369, 1965.
10. Mustoe, T. A., Cooter, R. D., Gold, M. H., et al. International clinical recommendations on scar management. Plast. Reconstr. Surg. 110: 560, 2002.
11. Draaijers, L. J., Tempelman, F. R., Botman, Y. A., et al. The patient and observer scar assessment scale: A reliable and feasible tool for scar evaluation. Plast. Reconstr. Surg. 113: 1960, 2004.
12. van de Kar, A. L., Corion, L. U. M. C., Smeulders, M. J. C., Draaijers, L. J., van der Horst, C. M. A. M., and van Zuijlen, P. P. M. The Patient and Observer Scar Assessment Scale (POSAS): A reliable and feasible tool for the evaluation of linear scars. Plast. Reconstr. Surg. 116: 514, 2005.
13. Cosman, B. The surgical treatment of keloids. Plast. Reconstr. Surg. 27: 335, 1961.
14. Sclafani, A. P., Gordon, L., Chadha, M., and Romo, T., III. Prevention of earlobe keloid recurrence with postoperative corticosteroid injections versus radiation therapy: A randomized, prospective study and review of the literature. Dermatol. Surg. 22: 569, 1996.
15. Chaudhry, M. R., Akhtar, S., Duvalsaint, F., Garner, L., and Lucente, F. E. Ear lobe keloids, surgical excision followed by radiation therapy: A 10-year experience. Ear Nose Throat J. 73: 779, 1994.
16. Kovalic, J. J., and Perez, C. A. Radiation therapy following keloidectomy: A 20-year experience. Int. J. Radiat. Oncol. Biol. Phys. 17: 77, 1989.
17. Ollstein, R. N., Siegel, H. W., Gillooley, J. F., and Barsa, J. M. Treatment of keloids by combined surgical excision and immediate postoperative X-ray therapy. Ann. Plast. Surg. 7: 281, 1981.
18. Enhamre, A., and Hammar, H. Treatment of keloids with excision and postoperative X-ray irradiation. Dermatologica 167: 90, 1983.
19. Sallstrom, K. O., Larson, O., Heden, P., Eriksson, G., Glas, J. E., and Ringborg, U. Treatment of keloids with surgical excision and postoperative X-ray radiation. Scand. J. Plast. Reconstr. Surg. Hand Surg. 23: 211, 1989.
20. Garg, M. K., Weiss, P., Sharma, A. K., et al. Adjuvant high dose rate brachytherapy (Ir-192) in the management of keloids which have recurred after surgical excision and external radiation. Radiother. Oncol. 73: 233, 2004.
21. Lo, T. C., Seckel, B. R., Salzman, F. A., and Wright, K. A. Single-dose electron beam irradiation in treatment and prevention of keloids and hypertrophic scars. Radiother. Oncol. 19: 267, 1990.
22. Brown, J. R., and Bromberg, J. H. Preliminary studies on the effect of time-dose patterns in the treatment of keloids. Radiology 80: 298, 1963.
23. Edsmyr, F., Larson, L. G., Onyango, J., Wanguru, S., and Wood, M. Radiotherapy in the treatment of keloids in East Africa. East Afr. Med. J. 50: 457, 1973.
24. Borok, T. L., Bray, M., Sinclair, I., Plafker, J., LaBirth, L., and Rollins, C. Role of ionizing irradiation for 393 keloids. Int. J. Radiat. Oncol. Biol. Phys. 15: 865, 1988.
25. Doornbos, J. F., Stoffel, T. J., Hass, A. C., et al. The role of kilovoltage irradiation in the treatment of keloids. Int. J. Radiat. Oncol. Biol. Phys. 18: 833, 1990.
26. Ragoowansi, R., Cornes, P. G., Moss, A. L., and Glees, J. P. Treatment of keloids by surgical excision and immediate postoperative single-fraction radiotherapy. Plast. Reconstr. Surg. 111: 1853, 2003.
27. Wagner, W., Alfrink, M., Micke, O., Schafer, U., Schuller, P., and Willich, N. Results of prophylactic irradiation in patients with resected keloids: A retrospective analysis. Acta Oncol. 39: 217, 2000.
28. Norris, J. E. Superficial x-ray therapy in keloid management: A retrospective study of 24 cases and literature review. Plast. Reconstr. Surg. 95: 1051, 1995.