A new approach using tissue alkaline phosphatase histochemistry to identify Crohn's disease

Pathology Research and Practice

Volumn 203, Issue 6, 2007, Pages 485-487

  Torres, M I ^a   Lorite, P ^a   Lopez Casado M A ^b   Rios A ^c  

^a UNIVERSITY OF JAÉN   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN DE LAS NIEVES   (Spain)

^c UNIVERSITY OF GRANADA   (Spain)

Author keywords

Alkaline phosphatase; Crohn's disease; Endotoxin; Ulcerative colitis

Indexed keywords

ALKALINE PHOSPHATASE;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DIAGNOSTIC VALUE; DIFFERENTIAL DIAGNOSIS; ENTERITIS; ENZYME ACTIVITY; ENZYME HISTOCHEMISTRY; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; ULCERATIVE COLITIS;

EID: 34249785649     PISSN: 03440338     EISSN: 16180631     Source Type: Journal    
DOI: 10.1016/j.prp.2007.02.003     Document Type: Article

References (10)

1. Brandtzaeg P., Haraldsen G., Helgeland L., Nilsen E.M., and Rugtveit J. New insights into the immunopathology of human inflammatory bowel disease. Drugs Today 35 (1999) 33-70
2. Bull T.J., McMinn E.J., Sidi-Boumedine K., Skull A., Durkin D., Neild P., Rhodes G., Pickup R., and Hermon-Taylor J. Detection and verification of Mycobacterium avium subsp. paratuberculosis in fresh ileocolonic mucosal biopsy specimens from individuals with and without Crohn's disease. J. Clin. Microbiol. 41 (2003) 2915-2923
3. Elson C.O. Commensal bacteria as targets in Crohn′s disease. Gastroenterology 119 (2000) 254-261
4. Fan M.Z., Adeola O., and Asem E.K. Characterization of brush border membrane-bound alkaline phosphatase activity in different segments of the porcine small intestine. J. Nutr. Biochem. 119 (1999) 299-305
5. Goldstein D.J., Rogers C.E., and Harris H. Expression of alkaline phosphatase loci in mammalian tissues. Proc. Natl. Acad. Sci. USA 77 (1980) 2857-2860
6. Henthorn P.S., Raducha M., Kadesch T., Weiss M.J., and Harris H. Sequence and characterization of the human intestinal alkaline phosphatase gene. J. Biol. Chem. 263 (1988) 120011-120019
7. Hinnebusch B.F., Siddique A., Henderson J.W., Malo M.S., Zhang W., Athaide C.P., Abedrapo M.A., Chen X., Yang V.W., and Hodin R.A. Enterocyte differentiation marker intestinal alkaline phosphatase is a target gene of the gut-enriched Kruppel-like factor. Am. J. Physiol. Gastrointest. Liver Physiol. 286 (2004) G23-G30
8. Hirano K., Iiizumi Y., Mori Y., Toyoshi K., Sugiera M., and Iino S. Role of alkaline phosphatase in phosphate uptake into brush border membrane vesicles from human intestinal mucosa. J. Biochem. Tokio 97 (1985) 1461-1466
9. Poelstra K., Bakker W.W., Klok P.A., Kamps J.A., Hardonk M.J., and Meijer D.K. A physiologic function for alkaline phsophatase: endotoxin detoxification. Lab. Invest. 76 (1997) 319-327
10. Sambrook J., Fritsch E.F., and Maniatis T. Molecular Cloning, A Laboratory Manual (1989), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY