Colony stimulating factors (blood growth factors) are promising but unproven for treating stroke

Stroke

Volumn 38, Issue 6, 2007, Pages 1997-1998

  Sprigg, Nikola ^a   Bath, Philip M W ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Colony stimunlating factors; Recovery; Stem cells; Stroke

Indexed keywords

COLONY STIMULATING FACTOR; COLONY STIMULATING FACTOR 1; ERYTHROPOIETIN; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; THROMBOPOIETIN;

BARTHEL INDEX; EMBASE; FUNCTIONAL ASSESSMENT; HUMAN; INFORMATION RETRIEVAL; MEDICAL ASSESSMENT; MEDICAL INFORMATION; MEDLINE; PRIORITY JOURNAL; RANKIN SCALE; SCISEARCH; SHORT SURVEY; STROKE; STROKE PATIENT; THERAPY EFFECT; TREATMENT RESPONSE;

EID: 34249782287     PISSN: 00392499     EISSN: None     Source Type: Journal    
DOI: 10.1161/STROKEAHA.107.482877     Document Type: Short Survey

References (7)

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2. Shyu WC, Lin SZ, Yang HI, Tzeng YS, Pang CY, Yen PS, Li H. Functional recovery of stroke rats induced by granulocyte colony-stimulating factor- stimulated cells. Circulation. 2004;110:1847-1854.
3. Sprigg N, Bath P, Zhao L, Willmot M, Gray LJ, Walker M, Dennis MS, Russel N. Granulocyte-colony stimulating factor mobilizes bone marrow stem cells in patients with sub-acute ischaemic stroke: The Stem cell Trial of recovery EnhanceMent after Stroke (STEMS) pilot randomized controlled trial. Stroke. 2006;37:2979-2983.
4. Zhang J, Deng M, Zhang Y, Sui W, Wang L, Sun A, Song H, Lu M, Fan D. A short-term assessment of recombinant human granulocyte-stimulating factor (rhg-csf) in treatment of acute cerebral infarction. Cerebrovascular Diseases. 2006;21(suppl 4):143. Abstract.
5. Ehrenreich H. The Multicenter-Erythropoietin-Stroke trial. Available at: http://www.epo-study.de/index_eng.html. Accessed August 2006.
6. Axaron Bioscience A. Treatment with ax200 for acute ischemic stroke. Available at: http://clinicaltrialsgov. Accessed August 2006.
7. Bath PMW. Stem cell Trial of recovery EnhanceMent after Stroke 2 (STEMS2): pilot randomised placebo-controlled trial of granulocyte-colony stimulating factor in mobilising bone marrow stem cells in sub-acute stroke. Available at:http://www.controlled-trials.com/ISRCTN63336619. Accessed November 2006.