메뉴 건너뛰기




Volumn 25, Issue 12, 2007, Pages 1443-1449

Mesalazine downregulates c-Myc in human colon cancer cells. A key to its chemopreventive action?

Author keywords

[No Author keywords available]

Indexed keywords

LIPOCORTIN 5; MESALAZINE;

EID: 34249781974     PISSN: 02692813     EISSN: 13652036     Source Type: Journal    
DOI: 10.1111/j.1365-2036.2007.03336.x     Document Type: Article
Times cited : (25)

References (30)
  • 1
    • 0038115225 scopus 로고    scopus 로고
    • Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea- induced colon cancer in F344 rats
    • Narisawa T, Fukaura Y. Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea-induced colon cancer in F344 rats. Dis Colon Rectum 2003 46 : 900 3.
    • (2003) Dis Colon Rectum , vol.46 , pp. 900-3
    • Narisawa, T.1    Fukaura, Y.2
  • 3
    • 0033950737 scopus 로고    scopus 로고
    • Mesalazine changes apoptosis and proliferation in normal mucosa of patients with sporadic polyps of the large bowel
    • Reinacher-Schick A, Seidensticker F, Petrasch S, et al. Mesalazine changes apoptosis and proliferation in normal mucosa of patients with sporadic polyps of the large bowel. Endoscopy 2000 32 : 245 54.
    • (2000) Endoscopy , vol.32 , pp. 245-54
    • Reinacher-Schick, A.1    Seidensticker, F.2    Petrasch, S.3
  • 4
    • 0032720159 scopus 로고    scopus 로고
    • Mesalazine-induced apoptosis of colorectal cancer: On the verge of a new chemopreventive era
    • Bus PJ, Nagtegaal ID, Verspaget HW, et al. Mesalazine-induced apoptosis of colorectal cancer: on the verge of a new chemopreventive era Aliment Pharmacol Ther 1999 13 : 1397 402.
    • (1999) Aliment Pharmacol Ther , vol.13 , pp. 1397-402
    • Bus, P.J.1    Nagtegaal, I.D.2    Verspaget, H.W.3
  • 5
    • 0028305575 scopus 로고
    • Risk factors for colorectal cancer in patients with ulcerative colitis: A case-control study
    • Pinczowksi D, Ekbom A, Baron J, Yuen J, Adami HO. Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study. Gastroenterology 1994 107 : 117 20.
    • (1994) Gastroenterology , vol.107 , pp. 117-20
    • Pinczowksi, D.1    Ekbom, A.2    Baron, J.3    Yuen, J.4    Adami, H.O.5
  • 6
    • 0029803955 scopus 로고    scopus 로고
    • Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: A retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire
    • Moody GA, Jayanthi V, Probert CS, Mac Kay H, Mayberry JF. Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire. Eur J Gastroenterol Hepatol 1996 8 : 1179 83.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 1179-83
    • Moody, G.A.1    Jayanthi, V.2    Probert, C.S.3    Mac Kay, H.4    Mayberry, J.F.5
  • 8
    • 0035144554 scopus 로고    scopus 로고
    • Proximal colorectal dysplasia or cancer in ulcerative colitis. the impact of primary sclerosing cholangitis and sulfasalazine: Results from a 20-year surveillance study
    • Lindberg BU, Broome U, Persson B. Proximal colorectal dysplasia or cancer in ulcerative colitis. The impact of primary sclerosing cholangitis and sulfasalazine: results from a 20-year surveillance study. Dis Colon Rectum 2001 44 : 77 85.
    • (2001) Dis Colon Rectum , vol.44 , pp. 77-85
    • Lindberg, B.U.1    Broome, U.2    Persson, B.3
  • 9
    • 0347994976 scopus 로고    scopus 로고
    • Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer?
    • Berstein CN, Blanchard JF, Metge C, Yogendran M. Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer? Am J Gastroenterol 2003 98 : 2784 8.
    • (2003) Am J Gastroenterol , vol.98 , pp. 2784-8
    • Berstein, C.N.1    Blanchard, J.F.2    Metge, C.3    Yogendran, M.4
  • 10
    • 21344446543 scopus 로고    scopus 로고
    • Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: A systematic review and metaanalysis of observational studies
    • Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 2005 100 : 1345 53.
    • (2005) Am J Gastroenterol , vol.100 , pp. 1345-53
    • Velayos, F.S.1    Terdiman, J.P.2    Walsh, J.M.3
  • 11
    • 0141539530 scopus 로고    scopus 로고
    • Review article: Mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease
    • Allgayer H. Review article: Mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease. Aliment Pharmacol Ther 2003 18 (Suppl. 2 10 4.
    • (2003) Aliment Pharmacol Ther , vol.18 , Issue.2 , pp. 10-4
    • Allgayer, H.1
  • 12
    • 0033543545 scopus 로고    scopus 로고
    • Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalazine is accompanied by decreased transcriptional activity
    • Egan LJ, Mays DC, Huntoon CJ, et al. Inhibition of interleukin-1- stimulated NF-kappaB RelA/p65 phosphorylation by mesalazine is accompanied by decreased transcriptional activity. J Biol Chem 1999 274 : 26448 53.
    • (1999) J Biol Chem , vol.274 , pp. 26448-53
    • Egan, L.J.1    Mays, D.C.2    Huntoon, C.J.3
  • 13
    • 0033637218 scopus 로고    scopus 로고
    • Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis
    • Bantel H, Berg C, Vieth M, Stolte M, Kruis W, Schulze-Osthoff K. Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis. Am J Gastroenterol 2000 95 : 3452 7.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3452-7
    • Bantel, H.1    Berg, C.2    Vieth, M.3    Stolte, M.4    Kruis, W.5    Schulze-Osthoff, K.6
  • 14
    • 0034322370 scopus 로고    scopus 로고
    • Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta
    • Weber CK, Liptay S, Wirth T, Adler G, Schmid RM. Suppression of NF-kappaB activity by sulfasalazine is mediated by direct inhibition of IkappaB kinases alpha and beta. Gastroenterology 2000 119 : 1209 18.
    • (2000) Gastroenterology , vol.119 , pp. 1209-18
    • Weber, C.K.1    Liptay, S.2    Wirth, T.3    Adler, G.4    Schmid, R.M.5
  • 15
    • 20944445862 scopus 로고    scopus 로고
    • Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma
    • Rousseaux C, Lefebvre B, Dubuquoy L, et al. Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator- activated receptor-gamma. J Exp Med 2005 201 : 1205 15.
    • (2005) J Exp Med , vol.201 , pp. 1205-15
    • Rousseaux, C.1    Lefebvre, B.2    Dubuquoy, L.3
  • 16
    • 0021819806 scopus 로고
    • Deregulation of c-myc gene expression in human colon carcinoma is not accompanied by amplification or rearrangement of the gene
    • Erisman MD, Rothberg PG, Diehl RE, Morse CC, Spandorfer JM, Astrin SM. Deregulation of c-myc gene expression in human colon carcinoma is not accompanied by amplification or rearrangement of the gene. Mol Cell Biol 1985 8 : 1969 76.
    • (1985) Mol Cell Biol , vol.8 , pp. 1969-76
    • Erisman, M.D.1    Rothberg, P.G.2    Diehl, R.E.3    Morse, C.C.4    Spandorfer, J.M.5    Astrin, S.M.6
  • 17
    • 0023215795 scopus 로고
    • Expression of c-myc in non-malignant and pre-malignant gastrointestinal disorders
    • Ciclitira PJ, Macartney JC, Evan G. Expression of c-myc in non-malignant and pre-malignant gastrointestinal disorders. J Pathol 1987 151 : 293 6.
    • (1987) J Pathol , vol.151 , pp. 293-6
    • Ciclitira, P.J.1    MacArtney, J.C.2    Evan, G.3
  • 18
    • 0026591443 scopus 로고
    • High c-myc protein expression in benign colorectal lesions correlates with the degree of dysplasia
    • Pavelic ZP, Pavelic L, Kuvelkar R, Gapany SR. High c-myc protein expression in benign colorectal lesions correlates with the degree of dysplasia. Anticancer Res 1992 12 : 171 5.
    • (1992) Anticancer Res , vol.12 , pp. 171-5
    • Pavelic, Z.P.1    Pavelic, L.2    Kuvelkar, R.3    Gapany, S.R.4
  • 20
    • 0036713995 scopus 로고    scopus 로고
    • Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents
    • Tao L, Kramer PM, Wang W, et al. Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents. Carcinogenesis 2002 23 : 1447 54.
    • (2002) Carcinogenesis , vol.23 , pp. 1447-54
    • Tao, L.1    Kramer, P.M.2    Wang, W.3
  • 21
    • 0036213316 scopus 로고    scopus 로고
    • Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane
    • Kishimoto Y, Yashima K, Morisawa T, Shiota G, Kawasaki H, Hasegawa J. Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane. J Gastroenterol 2002 37 : 186 93.
    • (2002) J Gastroenterol , vol.37 , pp. 186-93
    • Kishimoto, Y.1    Yashima, K.2    Morisawa, T.3    Shiota, G.4    Kawasaki, H.5    Hasegawa, J.6
  • 22
    • 0024333328 scopus 로고
    • Expression of c-myc oncogene in colorectal polyps as a biological marker for monitoring malignant potential
    • Imaseki H, Hayashi H, Taira M, et al. Expression of c-myc oncogene in colorectal polyps as a biological marker for monitoring malignant potential. Cancer 1989 64 : 704 9.
    • (1989) Cancer , vol.64 , pp. 704-9
    • Imaseki, H.1    Hayashi, H.2    Taira, M.3
  • 23
    • 0023919983 scopus 로고
    • The c-myc protein is constitutively expressed at elevated levels in colorectal carcinoma cell lines
    • Erisman MD, Scott JK, Watt RA, Astrin SM. The c-myc protein is constitutively expressed at elevated levels in colorectal carcinoma cell lines. Oncogene 1988 2 : 367 78.
    • (1988) Oncogene , vol.2 , pp. 367-78
    • Erisman, M.D.1    Scott, J.K.2    Watt, R.A.3    Astrin, S.M.4
  • 24
    • 0032483439 scopus 로고    scopus 로고
    • Identification of c-MYC as a target of the APC pathway
    • He TC, Sparks AB, Rago C, et al. Identification of c-MYC as a target of the APC pathway. Science 1998 281 : 1509 12.
    • (1998) Science , vol.281 , pp. 1509-12
    • He, T.C.1    Sparks, A.B.2    Rago, C.3
  • 25
    • 85047698730 scopus 로고    scopus 로고
    • Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity
    • Yamakawa-Karakida N, Sugita K, Inukai T, et al. Ligand activation of peroxisome proliferator-activated receptor gamma induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity. Cell Death Differ 2002 9 : 513 26.
    • (2002) Cell Death Differ , vol.9 , pp. 513-26
    • Yamakawa-Karakida, N.1    Sugita, K.2    Inukai, T.3
  • 26
    • 0036117576 scopus 로고    scopus 로고
    • Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells
    • Shimada T, Kojima K, Yoshiura K, Hiraishi H, Terano A. Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells. Gut 2002 50 : 658 64.
    • (2002) Gut , vol.50 , pp. 658-64
    • Shimada, T.1    Kojima, K.2    Yoshiura, K.3    Hiraishi, H.4    Terano, A.5
  • 27
    • 0025011866 scopus 로고
    • Topical and systemic availability of 5-aminosalicylate: Comparisons of three controlled release preparations in man
    • Christensen LA, Fallingborg J, Abildgaard K, et al. Topical and systemic availability of 5-aminosalicylate: comparisons of three controlled release preparations in man. Aliment Pharmacol Ther 1990 4 : 523 33.
    • (1990) Aliment Pharmacol Ther , vol.4 , pp. 523-33
    • Christensen, L.A.1    Fallingborg, J.2    Abildgaard, K.3
  • 28
    • 0025243656 scopus 로고
    • Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: Comparison of intraluminal colonic concentrations, serum values, and urinary excretion
    • Staerk Laursen L, Stokholm M, Bukhave K, Rask-Madsen J, Lauritsen K. Disposition of 5-aminosalicylic acid by olsalazine and three mesalazine preparations in patients with ulcerative colitis: comparison of intraluminal colonic concentrations, serum values, and urinary excretion. Gut 1990 31 : 1271 6.
    • (1990) Gut , vol.31 , pp. 1271-6
    • Staerk Laursen, L.1    Stokholm, M.2    Bukhave, K.3    Rask-Madsen, J.4    Lauritsen, K.5
  • 29
    • 0025909575 scopus 로고
    • Availability of mesalazine '5-aminosalicylic acid) from enemas and suppositories during steady-state conditions
    • Jacobsen BA, Abildgaard K, Rasmussen HH, et al. Availability of mesalazine '5-aminosalicylic acid) from enemas and suppositories during steady-state conditions. Scand J Gastroenterol 1991 26 : 374 8.
    • (1991) Scand J Gastroenterol , vol.26 , pp. 374-8
    • Jacobsen, B.A.1    Abildgaard, K.2    Rasmussen, H.H.3
  • 30
    • 0031832985 scopus 로고    scopus 로고
    • What dose of 5-aminosalicylic acid (mesalazine) in ulcerative colitis?
    • Riley SA. What dose of 5-aminosalicylic acid (mesalazine) in ulcerative colitis? Gut 1998 42 : 761 3.
    • (1998) Gut , vol.42 , pp. 761-3
    • Riley, S.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.