Endothelial cell chimerism by fluorescence in situ hybridization in gender mismatched renal allograft biopsies

Chinese Medical Journal

Volumn 120, Issue 10, 2007, Pages 859-862

  Bai, Hong Wei ^a   Shi, Bing Yi ^a   Qian, Ye Yong ^a   Na, Yan Qun ^b   Zeng, Xuan ^c   Zhong, Ding Rong ^c   Lu, Min ^d   Zou, Wan Zhong ^d   Wu, Sha Fei ^c  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b PEKING UNIVERSITY   (China)

^c PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^d PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Chimerism; Cold ischemia; Endothelium; Fluorescence; In situ hybridization; Kidney transplantation; Vascular

Indexed keywords

DIGOXIGENIN;

ARTICLE; BIOTINYLATION; CHROMOSOME ANALYSIS; CLINICAL ARTICLE; COLD ISCHEMIA; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIUM CELL; ENDOTHELIUM LESION; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GRAFT RECIPIENT; HISTOCOMPATIBILITY; HUMAN; HUMAN TISSUE; KIDNEY ALLOGRAFT REJECTION; KIDNEY BIOPSY; KIDNEY TRANSPLANTATION; MOLECULAR PROBE; TISSUE SECTION; VASCULAR ENDOTHELIUM; X CHROMOSOME; Y CHROMOSOME;

EID: 34249780520     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00029330-200705020-00001     Document Type: Article

References (19)

1. Medawar PB. Transplantation of tissues and organs: instruction. Br Med Bull 1965; 21: 97-99.
2. Rose ML. Endothelial cells as antigen-presenting cells: role in human transplant rejection. Cell Mol Life Sci 1998; 54: 965-978.
3. Lagaaij EL, Cramer-Knijnenburg GF, van Kemenade FJ, Van Es LA, Bruijn Jan A, Van Krieken JH. Endothelial cell chimerism after renal transplantation and vascular rejection. Lancet 2001; 357: 33-37.
4. Xu W, Baelde HJ, Lagaaij EL, Heee ED, Paul LC, Bruijn JA, et al. Endothelial cell chimerism after renal transplantation in a rat model. Transplantation 2002; 74: 1316-1320.
5. Pons JA, Yelamos J, Ramirez P, Oliver-Bonet M, Sanchez A, Rodriquez-Gaqo M, et al. Endothelial cell chimerism does not influence allograft tolerance in liver transplant patients after withdrawal of immunosuppression. Transplantation 2003; 75: 1045-1047.
6. Bayes-Genis A, Salido M, Sole Ristol F, Puig M, Brossa V, Camprecios M, et al. Host cell-derived cardiomyocytes in sex-mismatch cardiac allografts. Cardiovasc Res 2002; 56: 404-410.
7. Slinclair RA. Origin of endothelium in human renal allografts. Br Med J 1972; 4: 15-16.
8. Williams GM, ter Haar A, Parks LC, Krajewwski CA. Endothelial changes associated with hyperacute and chronic renal allograft rejection in man. Transpl Proc 1973; 5: 819-822.
9. Randhawa PS, Starzl T, Ramos HC, Nalesnik MA, Demetris J. Allograft surviving for 26 to 29 years following living-related kidney transplantation: analysis by light microscopy, in situ hybridization, and anti-HLA antibodies. Am J Kidney Dis 1994; 24: 72-77.
10. Andersen CB, Ladefoged SD, Larsen S. Cellular inflammatory infiltrates and renal cell turnover in kidney allografts: a study using in situ hybridization and combined in situ hybridization and immunohistochemistry with a Y chromosome-specific DNA probe and monoclonal antibodies. APMIS 1991; 99: 645-652.
11. Burdick JF, Russell PS, Winn HJ. Sensitivity of long-standing xenografts of rat hearts to humoral antibodies. J Immunol. 1979; 123: 1732-1735.
12. Bogman MJ, de Waal RM, Koene RA. Persistent expression of donor antigens in endothelium of long standing skin xenografts and vulnerability to destruction by specific antibodies. Trans plant Proc 1987; 19: 205-207.
13. van Poelgeest EP, Baelde HJ, Lagaaij EL, Sijpkens YW, Heee ED, Bruijn JA, et al. Endothelial cell chimerism occurs more often and earlier in female than in male recipients of kidney transplants. Kidney Int 2005; 68: 847-853.
14. Racusen LC, Solez K, Colvin RB, Bonsib SM, Castro MC, Cavallo T, et al. The Banff 97 working classification of renal allograft pathology. Kidny Int 1999; 55: 713-723.
15. Hruban RH, Long PP, Perlman EJ, Hutchins GM, Baumgartner WA, Baughman KL, et al. Fluorescence in situ hybridization for the Y chromosome can be used to detect cells of recipient origin in allografted hearts following cardiac transplantation. Am J Pathol 1993; 142: 975-980.
16. Salazar AB, McAlister VC, Gupta R, MacDonald AS. Circulating endothelial cells after transplantation. Lancet 2001; 357: 1450.
17. Ovuworie CA, Fox ER, Chow CM, Pascual M, Shih VE, Picard MH, et al. Vascular endothelial function in cyclosporine and tacrolimus treated renal transplant recipients. Transplantation 2001; 72: 1385-1388.
18. Rafii S, Shapiro F, Rimarachin J, Nachman RL, Ferris B, Weksler B, et al. Isolation and characterization of human bone marrow microvascular endothelial cells: hematopoietic progenitor cell adhesion. Blood 1994; 84: 10-19.
19. Poulsom R, Forbes SJ, Hodicala-Dilke K, Ryan E, Wyles S, Navaratnarasah S, et al. Bone marrow contributes to renal parenchymal turnover and regeneration. J Pathol 2001; 195: 229-235.