Abnormal sensorimotor integrative function of the larynx in congenital laryngomalacia: A new theory of etiology

Laryngoscope

Volumn 117, Issue 6 SUPPL., 2007, Pages 1-33

  Thompson, Dana Mara ^a,b,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b Mayo Eugenio Litta Children's Hospital   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

Gastroesophageal reflux disease; Laryngeal adductor reflex; Laryngomalacia; Laryngopharyngeal reflux; Sensory testing; Stridor; Supraglottoplasty

Indexed keywords

ABNORMAL SENSATION; APGAR SCORE; COMORBIDITY; COMPARATIVE STUDY; CORRELATION FUNCTION; DISEASE COURSE; DISEASE SEVERITY; EPIGLOTTIS; FEEDING; FEMALE; FOLLOW UP; GASTROESOPHAGEAL REFLUX; GENETIC DISORDER; HEART DISEASE; HUMAN; HUMAN TISSUE; INFORMATION PROCESSING; LARYNGOMALACIA; LARYNX; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NEUROLOGIC DISEASE; OUTCOME ASSESSMENT; PEDIATRICS; PRIORITY JOURNAL; PROSPECTIVE STUDY; REFLEX; RETROSPECTIVE STUDY; REVIEW; SENSORIMOTOR FUNCTION; SENSORIMOTOR INTEGRATION; SENSORY EVALUATION; SUPRAGLOTTOPLASTY; SYMPTOM; TERTIARY HEALTH CARE; THEORY; TRACHEOTOMY;

AGE OF ONSET; CHILD, PRESCHOOL; COMORBIDITY; DEMOGRAPHY; DIFFERENTIAL THRESHOLD; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GASTROESOPHAGEAL REFLUX; HUMANS; LARYNGEAL DISEASES; LARYNGEAL MUSCLES; MALE; MUSCLE WEAKNESS; PHARYNGEAL DISEASES; PROSPECTIVE STUDIES; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SOMATOSENSORY DISORDERS;

EID: 34249777237     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MLG.0b013e31804a5750     Document Type: Review

References (97)

1. Holinger LD, Konior RJ. Surgical management of severe laryngomalacia. Laryngoscope 1989;99:136-142.
2. Baxter MR. Congenital laryngomalacia. Can J Anaesth 1994; 41:332-339.
3. Shah UK, Wetmore RF. Laryngomalacia: a proposed classification form. Int J Pediatr Otorhinolaryngol 1998;46:21-26.
4. Olney DR, Greinwald JH Jr, Smith RJ, Bauman NM. Laryngomalacia and its treatment. Laryngoscope 1999;109:1770-1175.
5. Holinger PH, Johnson KC, Schiller F. Congenital anomalies of the larynx. Ann Otol Rhinol Laryngol 1954;63:581-606.
6. Holinger PH, Brown W. Congenital webs, cyst, laryngoceles and other anomalies of the larynx. Ann Otol Rhinol Laryngol 1967;76:744-752.
7. Ferguson CF. Congenital abnormalities of the infant larynx. Otolaryngol Clin North Am 1970;3:185-200.
8. Holinger LD. Etiology of stridor in the neonate, infant and child. Ann Otol Rhinol Laryngol 1980;89:397-400.
9. Narcy P, Bobin S, Contencin P, et al. Anomalies laryngies du noujveau-ne apropos de 687 observations. Ann Otolaryngol Chir Cervicofac 1984;101:363-373.
10. Friedman EM, Vastola AP, McGill TJ, Healy GB. Chronic pediatric stridor: etiology and outcome. Laryngoscope 1990;100:277-280.
11. Giannoni C, Sulek M, Friedman EM, Duncan NO III. Gastroesophageal reflux association with laryngomalacia: a prospective study. Int J Pediatr Otorhinolaryngol 1998;43:11-20.
12. Matthews BL, Little JP, McGuirt WF, Koufman JA. Reflux in infants with laryngomalacia: results of 24-hour double-probe pH monitoring. Otolaryngol Head Neck Surg 1999;120:860-864.
13. Remacle M, Bodart E, Lawson G, et al. Use of the CO2-laser micropoint micromanipulator for the treatment of laryngomalacia. Eur Arch Otol Rhinol Laryngol 1996;253:401-404.
14. Roger G, Denoyelle F, Triglia JM, Garabedian EN. Severe laryngomalacia: surgical indications and results in 115 patients. Laryngoscope 1995;105:1111-1117.
15. Bibi H, Khvolis E, Shoseyov D, et al. The prevalence of gastroesophageal reflux in children with tracheomalacia and laryngomalacia. Chest 2001;119:409-413.
16. Halstead LA. Role of gastroesophageal reflux in pediatric upper airway disorders. Otolaryngol Head Neck Surg 1999;120:208-214.
17. Yellon RF, Goldberg H. Update on gastroesophageal reflux disease in pediatric airway disorders. Am J Med 2001;111(Suppl 8A):78S-84S.
18. Garabedian EN, Roger G, Denoyelle F, Triglia JM. Severe laryngomalacia: surgical indications and results. Pediatr Pulmonol Suppl 1997;16:292.
19. Milczuk HA, Johnson SM. Effect on families and caregivers of caring for a child with laryngomalacia. Ann Otol Rhinol Laryngol 2000;109:348-354.
20. Prescott CA. The current status of corrective surgery for laryngomalacia. Am J Otolaryngol 1991;12:230-235.
21. Lane RW, Weider DJ, Steinem C, Marin-Padilla M. Laryngomalacia. A review and case report of surgical treatment with resolution of pectus excavatum. Arch Otolaryngol 1984;110:546-551.
22. Seid AB, Park SM, Kearns MJ, Gugenheim S. Laser division of the aryepiglottic folds for severe laryngomalacia. Int J Pediatr Otorhinolaryngol 1985;10:153-158.
23. Solomons NB, Prescott CA. Laryngomalacia. A review and the surgical management for severe cases. Int J Pediatr Otorhinolaryngol 1987;13:31-39.
24. Zalzal GH, Anon JB, Cotton RT. Epiglottoplasty for the treatment of laryngomalacia. Ann Otol Rhinol Laryngol 1987;96:72-76.
25. Marcus CL, Crockett DM, Davidson Ward SL. Evaluation of epiglottoplasty as a treatment for severe laryngomalacia. J Peds 1990;117:706-710.
26. Polonovski JM, Contencin P, Francois M, et al. Aryepiglottic fold excision for the treatment of severe laryngomalacia. Ann Otol Rhinol Laryngol 1990;99:625-627.
27. Jani P, Koltai P, Ochi JW, Bailey CM. Surgical treatment of laryngomalacia. J Laryngol Otol 1991;105:1040-1045.
28. Toynton SC, Saunders MW, Bailey CM. Aryepiglottoplasty for laryngomalacia: 100 consecutive cases. J Laryngol Otol 2001;115:35-38.
29. McClurg FL, Evans DA. Laser laryngoplasty for laryngomalacia. Laryngoscope 1994;104:247-252.
30. Denoyelle F, Mondain M, Gresillon N, et al. Failures and complications of supraglottoplasty in children. Arch Otolaryngol Head Neck Surg 2003;129:1077-1080.
31. Belmont JR, Grundfast K. Congenital laryngeal stridor (laryngomalacia): etiologic factors and associated disorders. Ann Otol Rhinol Laryngol 1984;93:430-437.
32. Mitchell RB, Call E, Kelly J. Ear, nose and throat disorders in children with Down syndrome. Laryngoscope 2003;113:259-263.
33. Lee SL, Cheung YF, Leung MP, et al. Airway obstruction in children with congenital heart disease: assessment by flexible bronchoscopy. Pediatr Pulmonol 2002;34:304-311.
34. Karakas K, Percin EF, Percin S. Surgical risk factors in Larsen's syndrome. Acta Orthop Belg 2000;66:495-498.
35. Markert ML, Majure M, Harville TO, et al. Severe laryngomalacia and bronchomalacia in DiGeorge syndrome and CHARGE association. Pediatr Pulmonol 1997;24:364-369.
36. Froehlich P, Seid AB, Denoyelle F, et al. Discoordinate pharyngolaryngomalacia. Int J Pediatr Otorhinolaryngol 1997;39:9-18.
37. McCray PB Jr, Crockett DM, Wagener JS, Thies DJ. Hypoxia and hypercapnia in infants with mild laryngomalacia. Am J Dis Child 1988;142:896-899.
38. Voisin M, Lesbros D, Ariole P, Jean R. Cardiac failure complicating laryngomalacia in a newborn infant (letter) [in French]. Arch Fr Pediatr 1984;41:728-729.
39. Barthez E, Rilliet F. Traiate Clinique et Pratique des Maladies des Enfants. Paris: Germer Bailliere, 1843:484-488.
40. Sutherland GA, Lack HL. Congenital laryngeal obstruction. Lancet 1897;2:653-655.
41. Hill FT. Congenital laryngeal stridor. Laryngoscope 1930;40: 44-64.
42. Mc Swiney PF, Cavanagh NP, Languth P. Outcome in congenital stridor (laryngomalacia). Arch Dis Child 1977;52:215-218.
43. Kelemen G. Congenital laryngeal stridor. Arch Otolaryngol 1953;58:245-268.
44. Shulman JB, Hollister DW, Thibeault DW, Krugman ME. Familial laryngomalacia: a case report. Laryngoscope 1976;86:84-91.
45. Schwartz L. Congenital laryngeal stridor (inspiratory laryngeal collapse). A new theory as to its underlying cause and the desirability of a change in terminology. Arch Otolaryngol 1944;39:403-412.
46. Thomson J, Turner A. On the causation of congenital laryngeal stridor of infants. BMJ 1900;2:1561-1563.
47. Apley J. The infant with stridor: a follow-up survey of 80 cases. Arch Dis Child 1953;28:423-435.
48. Benians RC, Benson PF, Sherwood T, Spector RG. Intellectual impairment in congenital laryngeal stridor. Guy's Hosp Report 1964;113:360-367.
49. Hui Y, Gaffney R, Crysdale WS. Laser aryepiglottoplasty for the treatment of neurasthenic laryngomalacia in cerebral palsy. Ann Otol Rhinol Laryngol 1995;104:432-436.
50. Amin MR, Isaacson G. State-dependent laryngomalacia. Ann Otol Rhinol Laryngol 1997;106:887-890.
51. Archer SM. Acquired flaccid larynx. A case report supporting the neurologic theory of laryngomalacia. Arch Otolaryngol Head Neck Surg 1992;131:896-899.
52. Woo P. Acquired laryngomalacia: epiglottis prolapse as a cause of airway obstruction [see comments]. Ann Otol Rhinol Laryngol 1992;101:314-320.
53. Peron DL, Graffino DB, Zenker DO. The redundant aryepiglottic fold: report of a new cause of stridor. Laryngoscope 1988;98:659-663.
54. Kletzker GR, Bastian RW. Acquired airway obstruction from histologically normal, abnormally mobile supraglottic soft tissues. Laryngoscope 1990;100:375-379.
55. Lucier GE, Storey AT, Sessle BJ. Effects of upper respiratory tract stimuli on neonatal respiration: reflex and single neuron analyses in the kitten. Biol Neonate 1979;35:82-89.
56. Lee JC, Stoll BJ, Downing SE. Properties of the laryngeal chemoreflex in neonatal piglets. Am J Physiol 1977;233:R30-R36.
57. Downing SE, Lee JC. Laryngeal chemosensitivity: a possible mechanism for sudden infant death. Pediatrics 1975;55:640-649.
58. Lucier GE, Daynes J, Sessle BJ. Laryngeal reflex regulation: peripheral and central neural analyses. Exp Neurol 1978;62:200-213.
59. Storey AT, Johnson P. Laryngeal water receptors initiating apnea in the lamb. Exp Neurol 1975;47:42-55.
60. Aviv JE, Martin JH, Keen MS, Debell M, Blitzer A. Air pulse quantification of supraglottic and pharyngeal sensation: a new technique. Ann Otol Rhinol Laryngol 1993;102:777-780.
61. Aviv JE, Martin JH, Kim T, et al. Laryngopharyngeal sensory discrimination testing and the laryngeal adductor reflex. Ann Otol Rhinol Laryngol 1999;108:725-730.
62. Aviv JE, Sacco RL, Thomson J, et al. Silent laryngopharyngeal sensory deficits after stroke. Ann Otol Rhinol Laryngol 1997;106:87-93.
63. Aviv JE, Martin JH, Sacco RL, et al. Supraglottic and pharyngeal sensory abnormalities in stroke patients with dysphagia. Ann Otol Rhinol Laryngol 1996;105:92-97.
64. Aviv JE, Kim T, Sacco RL, et al. FEESST: a new bedside endoscopic test of the motor and sensory components of swallowing. Ann Otol Rhinol Laryngol 1998;107:378-387.
65. Link DT, Willging JP, Miller CK, et al. Pediatric laryngopharyngeal sensory testing during flexible endoscopic evaluation of swallowing (FEES): feasible and correlative. Ann Otol Rhinol Laryngol 2000;109:899-905.
66. Thompson DM. Laryngopharyngeal sensory testing and assessment of airway protection in pediatric patients. Am J Med 2003;115(Suppl 3A):166S-168S.
67. Thompson DM, Rutter M, Willging JP, et al. Altered laryngeal sensation: a potential etiology of apnea of infancy. Ann Otol Rhinol Laryngol 2005;114:258-263.
68. Aviv JE. Sensory discrimination in the larynx and hypopharynx. Otolaryngol Head Neck Surg 1997;116:331-334.
69. Aviv JE, Martin JH, Jones ME, et al. Age-related changes in pharyngeal and supraglottic sensation. Ann Otol Rhinol Laryngol 1994;103:749-752.
70. Aviv JE. Effects of aging on sensitivity of the pharyngeal and supraglottic areas. Am J Med 1997;103:74S-76S.
71. Suskind DL, Thompson DM, Gulati M, et al. Improved infant swallowing after GER treatment: a function of improved laryngeal sensation? Laryngoscope 2006;116:1397-1403.
72. Aviv JE, Liu H, Parides M, et al. Laryngopharyngeal sensory deficits in patients with laryngopharyngeal reflux and dysphagia. Ann Otol Rhinol Laryngol 2000;109:1000-1006.
73. Close LG. Laryngopharyngeal manifestations of reflux: diagnosis and therapy. Eur J Gastroenterol Hepatol 2002;14(Suppl 1):S23-S27.
74. Nielson DW, Ku PL, Egger M. Topical lidocaine exaggerates laryngomalacia during flexible bronchoscopy. Am J Respir Crit Care Med 2000;161:147-151.
75. Sang Q, Goyal RK. Swallowing reflex and brain stem neurons activated by superior laryngeal nerve stimulation in the mouse. Am J Physiol Gastrointest Liver Physiol 2001;280:G191-G200.
76. Broussard DL, Altschuler SM. Brainstem viscerotopic organization of afferents and efferents involved in the control of swallowing. Am J Med 2000;108(Suppl 4a):79S-86S.
77. Kuypers HG. Corticobular connexions to the pons and lower brain-stem in man: an anatomical study. Brain 1958;81:364-388.
78. Kuypers HG. An anatomical analysis of cortico-bulbar connexions to the pons and lower brain stem in the cat. J Anat 1958;92:198-218.
79. Berkowitz RG, Sun QJ, Goodchild AK, Pilowsky PM. Serotonin inputs to laryngeal constrictor motoneurons in the rat. Laryngoscope 2005;115:105-109.
80. Sasaki CT, Jassin B, Kim YH, et al. Central facilitation of the glottic closure reflex in humans. Ann Otol Rhinol Laryngol 2003;112:293-297.
81. Sasaki CT, Ho S, Kim YH. Critical role of central facilitation in the glottic closure reflex. Ann Otol Rhinol Laryngol 2001;110:401-405.
82. Jean A. Brain stem control of swallowing: neuronal network and cellular mechanisms. Physiol Rev 2001;81:929-969.
83. McSwiney PF, Cavanagh NP, Languth P. Outcome in congenital stridor (laryngomalacia). Arch Dis Child 1977;52: 215-218.
84. Reddy DK, Matt BH. Unilateral vs. bilateral supraglottoplasty for severe laryngomalacia in children. Arch Otolaryngol Head Neck Surg 2001;127:694-699.
85. Issel EP, Eggers H, Plath C, et al. The apgar value of the newborn and its prognostic value for the course of the neonatal period. Zentralbl Gynakol 1976;98:1618-1625.
86. Nelson KB, Ellenberg JH. Apgar scores as predictors of chronic neurologic disability. Pediatrics 1981;68:36-44.
87. Kamper J, Moller J. Long-term prognosis of infants with idiopathic respiratory distress syndrome. Follow-up studies in infants surviving after the introduction of continuous positive airway pressure. Acta Paediatr Scand 1979;68:149-154.
88. Zeitouni A, Manoukian J. Epiglottoplasty in the treatment of laryngomalacia. J Otolaryngol 1993;22:29-33.
89. Smith GJ, Cooper DM. Laryngomalacia and inspiratory obstruction in later childhood. Arch Dis Child 1981;56:345-349.
90. Lees D. larynx from an infant with a peculiar form of obstructed respiration. Trans Pathol Soc Lond 1883;34:19.
91. Variot G. Un cas de respiration stridoreuse des nouveau-nes avec autopsie. Soc Med Hop 1898;27:490-495.
92. Iglauer S. Epiglottidectomy for the relief of congenital laryngeal stridor. Laryngoscope 1922;32:56-59.
93. Hasslinger F. Diagnostik and therapie des stridor congenitus. Z Hals Nasen Ohrenheilkd 1928;21:223-35.
94. Rudolph CD, Mazur LJ, Liptak GS, et al. Guidelines for evaluation and treatment of gastroesophageal reflux in infants and children: recommendations of the North American Society for Pediatric Gastroenterology and Nutrition [see comment]. J Pediatr Gastroenterol Nutr 2001;32:S1-S31.
95. Khoury RM, Katz PO, Hammod R, Castell DO. Bedtime ranitidine does not eliminate the need for a second daily dose of omeprazole to suppress nocturnal gastric pH. Aliment Pharmacol Ther 1999;13:675-678.
96. Peghini PL, Katz PO, Castell DO. Ranitidine controls nocturnal gastric acid breakthrough on omeprazole: a controlled study in normal subjects. Gastroenterology 1998;115:1335-1339.
97. Masters IB, Chang AB, Patterson L, et al. Series of laryngomalacia, tracheomalacia, and bronchomalacia disorders and their associations with other conditions in children. Pediatr Pulmonol 2002;34:189-195.