Sensitive and specific liquid chromatography-tandem mass spectrometric method for the quantitation of dexmedetomidine in pediatric plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 195-201

  Lee, James I ^a   Su, Felice ^a   Shi, Heng ^a   Zuppa, Athena F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Dexmedetomidine; LC MS MS; Pediatric; Pharmacokinetics

Indexed keywords

BIOASSAY; MASS SPECTROMETRY; PEDIATRICS; PHARMACOKINETICS; PLASMA (HUMAN);

DEXMEDETOMIDINE; INTENSIVE CARE UNIT; LIPOPHILIC IMIDAZOLE; QUANTITATION;

LIQUID CHROMATOGRAPHY;

ACETONITRILE; AMMONIUM ACETATE; BUFFER; DEXMEDETOMIDINE; FORMIC ACID; METHANOL; SOLVENT; WATER;

ACCURACY; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG ISOLATION; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; QUALITY CONTROL; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

ADRENERGIC ALPHA-AGONISTS; CHILD; DEXMEDETOMIDINE; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 34249743723     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.01.013     Document Type: Article

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