Development and validation of a gas chromatography-mass spectrometry method for the determination of isoimperatorin in rat plasma and tissue: Application to the pharmacokinetic and tissue distribution study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 852, Issue 1-2, 2007, Pages 473-478

  Wang, Sicen ^a   Chen, Qinhua ^a   He, Langchong ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Angelica dahuricae; GC MS; Isoimperatorin; Pharmacokinetics; Tissue distribution

Indexed keywords

CONCENTRATION (PROCESS); GAS CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; RATS; TISSUE;

ANGELICA DAHURICAE; ISOIMPERATORIN; TISSUE DISTRIBUTION;

BIOMEDICAL ENGINEERING;

ETHER DERIVATIVE; ISOIMPERATORIN; PETROLEUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DISTRIBUTION; GAS CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; RAT; SIGNAL NOISE RATIO; TISSUE DISTRIBUTION; VALIDATION PROCESS;

ANIMALS; AREA UNDER CURVE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; PSORALENS; RATS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION;

RATTUS;

EID: 34249720055     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.02.015     Document Type: Article

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