Cognitive and Behavioral Dysfunction in Children With Hypothalamic Hamartoma and Epilepsy

Seminars in Pediatric Neurology

Volumn 14, Issue 2, 2007, Pages 65-72

  Prigatano, George P ^a  

^a BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

behavior; cognition; epilepsy; hypothalamic hamartoma; memory; neuropsychology

Indexed keywords

ARTICLE; BEHAVIOR DISORDER; COGNITIVE DEFECT; ELECTROPHYSIOLOGY; EPILEPSY; GELASTIC SEIZURE; HAMARTOMA; HUMAN; MENTAL DISEASE; NEUROANATOMY; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; RISK FACTOR; SEIZURE;

BEHAVIORAL SYMPTOMS; CHILD; COGNITION DISORDERS; EPILEPSY; HAMARTOMA; HUMANS; HYPOTHALAMIC DISEASES; MALE; NEUROPSYCHOLOGICAL TESTS;

EID: 34249707818     PISSN: 10719091     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spen.2007.03.004     Document Type: Article

References (20)

1. Kupfermann I. Hypothalamus and the limbic system. In: Kandell E., Schwartz J.H., and Jessell T.M. (Eds). Principles of Neural Science. (ed 3). (1991), Elsevier, Amsterdam 433-460
2. Saper C.B. The hypothalamus. In: Paxinos G., and Mai J.K. (Eds). The Human Nervous System (2004), Elsevier, Amsterdam 513-550
3. Nguyen D., Singh S., Zaatreh M., et al. Hypothalamic hamartomas: Seven cases and review of the literature. Epilepsy Behav 4 (2003) 246-258
4. Valdueza J.M., Cristante L., Dammann O., et al. Hypothalamic hamartomas: With special reference to gelastic epilepsy and surgery. Neurosurgery 34 (1994) 949-958
5. Kerrigan J.F., Ng Y., Chung S., et al. The hypothalamic hamartoma: A model of subcortical epileptogenesis and encephalopathy. Semin Pediatr Neurol 12 (2005) 119-131
6. Berkovic S.F., Andermann F., Melanson D., et al. Hypothalamic hamartomas and ictal laughter: Evolution of a characteristic epileptic syndrome and diagnostic value of magnetic resonance imaging. Ann Neurol 23 (1988) 429-439
7. Arita K., Ikawa F., Kurisu K., et al. The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma. J Neurosurg 91 (1999) 212-220
8. Freeman J.L., Coleman L.T., Wellard R.M., et al. MR imaging and spectroscopic study of epileptogenic hypothalamic hamartomas: Analysis of 72 cases. Am J Neuroradiol 25 (2004) 450-462
9. Deonna T., and Ziegler A.L. Hypothalamic hamartoma, precocious puberty and gelastic seizures: A special model of "epileptic" developmental disorder. Epileptic Disord 2 (2000) 33-37
10. Frattali D.M., Liow K., Craig G.H., et al. Cognitive deficits in children with gelastic seizures and hypothalamic hamartoma. Neurology 51 (2001) 43-36
11. Striano S., Striano P., Sarappa C., et al. The clinical spectrum and natural history of gelastic epilepsy-hypothalamic hamartoma syndrome. Seizure 14 (2005) 232-239
12. Quiske A., Frings L., Wagner K., et al. Cognitive functions in juvenile and adult patients with gelastic epilepsy due to hypothalamic hamartoma. Epilepsia 47 (2006) 153-158
13. Prigatano GP, Wethe JV, Rekate HL, et al: Neuropsychological dysfunction in patients with hypothalamic hamartomas and refractory epilepsy. Am Epilepsy Soc (Abstract, 2006). Available at: http://www.aesnet.org/Visitors/AnnualMeeting/Abstractsnew/dsp_Abstract.cfm?id=320. Accessed May 9, 2007
14. Weissenberger A.A., Dell M.L., Liow K., et al. Aggression and psychiatric comorbidity in children with hypothalamic hamartomas and their unaffected siblings. J Am Acad Child Adolesc Psychiatry 40 (2001) 696-703
15. Savard G., Bhanji N.H., Dubeau F., et al. Psychiatric aspects of patients with hypothalamic hamartoma and epilepsy. Epileptic Dis 5 (2003) 229-234
16. Prigatano GP, Gray J, Wethe JV: Psychiatric diagnoses applied to children and adults with HH and refractory epilepsy. Barrow Quarterly 22:4-9
17. Lesser R.P., Luders H., Wyllie E., et al. Mental deterioration in epilepsy. Epilepsia 27 suppl 2 (1986) S105-S123
18. Trimble M.R., and Thompson P.J. Neuropsychological aspects of epilepsy. In: Grant I., and Adams K.M. (Eds). Neuropsychological Assessment of Neuropsychiatric Disorders (1986), Oxford University Press, New York 321-346
19. Herman B.P., Seidenberg M., and Bell B. The neurodevelopmental impact of childhood onset temporal lobe epilepsy on brain structure and function and the risk of progressive cognitive effects. In: Sutula T., and Pitkanen A. (Eds). Progress in Brain Research vol 135 (2002), Elsevier Science BV, Amsterdam 429-438
20. Trimble M.R. Cognitive hazards of seizure disorders. Epilepsia 29 (1988) S19-S24