Long-lasting hypotensive action of stable preparations of dinitrosyl-iron complexes with thiol-containing ligands in conscious normotensive and hypertensive rats

Nitric Oxide - Biology and Chemistry

Volumn 16, Issue 4, 2007, Pages 413-418

  Lakomkin, Vladimir L ^a   Vanin, Anatoly F ^b   Timoshin, Alexander A ^a   Kapelko, Valery I ^a   Chazov, Evgeny I ^a  

^a N N BLOKHIN NATIONAL MEDICAL RESEARCH CENTER OF ONCOLOGY   (Russian Federation)

^b SEMENOV INSTITUTE OF CHEMICAL PHYSICS   (Russian Federation)

Author keywords

Dinitrosyl iron complexes; Hypertension; Nitric oxide; SHR

Indexed keywords

CYSTEINE; DINITROSYL IRON DERIVATIVE; GLUTATHIONE; IRON; IRON DERIVATIVE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; S NITROSOCYSTEINE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTERY CATHETER; ARTICLE; BLOOD PRESSURE; CAROTID ARTERY; CONSCIOUSNESS; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; DRY POWDER; ELECTRON SPIN RESONANCE; HYPERTENSION; HYPOTENSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SUSTAINED RELEASE PREPARATION;

ANIMALS; ANTIHYPERTENSIVE AGENTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; HYPERTENSION; HYPOTENSION; IRON; LIGANDS; MALE; NITRIC OXIDE DONORS; NITROGEN OXIDES; RATS; RATS, INBRED SHR; RATS, WISTAR; SULFHYDRYL COMPOUNDS; WAKEFULNESS; WATER;

RATTUS;

EID: 34249698191     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.niox.2007.03.002     Document Type: Article

References (12)

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