Validation of a clinical prognostic model to identify low-risk patients with pulmonary embolism

Journal of Internal Medicine

Volumn 261, Issue 6, 2007, Pages 597-604

  Aujesky, D ^a,h   Perrier, A ^b   Roy, P M ^c   Stone, R A ^d,e   Cornuz, J ^a   Meyer, G ^f   Obrosky, D S ^e   Fine, M J ^e,g  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c UNIVERSITÉ D'ANGERS   (France)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^e VETERANS AFFAIRS MEDICAL CENTER   (United States)

^f HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^g UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^h LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

Mortality; Prognostic model; Pulmonary embolism; Validation

Indexed keywords

ACCURACY; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; FEMALE; HUMAN; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MODEL; MORTALITY; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; VALIDATION STUDY;

AGED; FEMALE; HEALTH STATUS INDICATORS; HUMANS; MALE; MIDDLE AGED; PROBABILITY; PROGNOSIS; PROSPECTIVE STUDIES; PULMONARY EMBOLISM; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY;

EID: 34249678675     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2007.01785.x     Document Type: Article

References (31)

1. Wells PS, Kovacs MJ, Bormanis J et al. Expanding eligibility for outpatient treatment of deep venous thrombosis and pulmonary embolism with low-molecular-weight heparin: a comparison of patient self-injection with homecare injection. Arch Intern Med 1998 158 : 1809 12.
2. Kovacs MJ, Anderson D, Morrow B, Gray L, Touchie D, Wells PS. Outpatient treatment of pulmonary embolism with dalteparin. Thromb Haemost 2000 83 : 209 11.
3. Beer JH, Burger M, Gretener S, Bernard-Bagattini S, Bounameaux H. Outpatient treatment of pulmonary embolism is feasible and safe in a substantial proportion of patients. J Thromb Haemost 2003 1 : 186 7.
4. Siragusa S, Arcara C, Malato A et al. Home therapy for deep vein thrombosis and pulmonary embolism in cancer patients. Ann Oncol 2005 16 : iv136 iv139.
5. Wells PS, Anderson DR, Rodger MA et al. A randomized trial comparing 2 low-molecular-weight heparins for the outpatient treatment of deep vein thrombosis and pulmonary embolism. Arch Intern Med 2005 165 : 733 8.
6. British Thoracic Society. British Thoracic Society guidelines for the management of suspected acute pulmonary embolism. Thorax 2003 58 : 470 83.
7. Wells PS. Outpatient treatment of patients with deep-vein thrombosis or pulmonary embolism. Curr Opin Pulm Med 2001 7 : 360 4.
8. Janata K. Managing pulmonary embolism. BMJ 2003 326 : 1341 2.
9. Ong BS, Karr MA, Chan DK, Frankel A, Shen Q. Management of pulmonary embolism in the home. Med J Aust 2005 183 : 239 42.
10. Olsson CG, Bitzen U, Olsson B et al. Outpatient tinzaparin therapy in pulmonary embolism quantified with ventilation/perfusion scintigraphy. Med Sci Monit 2006 12 : PI9 13.
11. Rhodes S, Bond S. Shifting pulmonary embolism management to primary care. Nurs Times 2006 102 : 23 4.
12. Aujesky D, Obrosky DS, Stone RA et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med 2005 172 : 1041 6.
13. Aujesky D, Roy PM, Le Manach CP et al. Validation of a model to predict adverse outcomes in patients with pulmonary embolism. Eur Heart J 2006 27 : 476 81.
14. Perrier A, Howarth N, Didier D et al. Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism. Ann Intern Med 2001 135 : 88 97.
15. Perrier A, Roy PM, Aujesky D et al. Diagnosing pulmonary embolism in outpatients with clinical assessment, D-dimer measurement, venous ultrasound, and helical computed tomography: a multicenter management study. Am J Med 2004 116 : 291 9.
16. Perrier A, Roy PM, Sanchez O et al. Multidetector-row computed tomography in suspected pulmonary embolism. N Engl J Med 2005 352 : 1760 8.
17. Roy PM, Meyer G, Vielle B et al. Appropriateness of diagnostic management and outcomes of suspected pulmonary embolism. Ann Intern Med 2006 144 : 157 64.
18. Roy PM, Colombet I, Durieux P, Chatellier G, Sors H, Meyer G. Systematic review and meta-analysis of strategies for the diagnosis of suspected pulmonary embolism. BMJ 2005 331 : 259.
19. Fine MJ, Auble TE, Yealy DM et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 1997 336 : 243 50.
20. Fletcher RW, Fletcher SW. Diagnosis. In : Fletcher RW, Fletcher SW, eds. Clinical Epidemiology. The Essentials. Philadelphia : Lippincott Williams & Wilkins, 2005 38 42.
21. Justice AC, Covinsky KE, Berlin JA. Assessing the generalizability of prognostic information. Ann Intern Med 1999 130 : 515 24.
22. Aujesky D, Smith KJ, Cornuz J, Roberts MS. Cost-effectiveness of low-molecular-weight heparin for treatment of pulmonary embolism. Chest 2005 128 : 1601 10.
23. Kozak LJ, Lees KA, Frances CJ. National Hospital Discharge Survey: 2003 annual summary with detailed diagnosis and procedure data. National Center for Health Statistics. Vital Health Stat 2006 13 : 62.
24. Nendaz MR, Bandelier P, Aujesky D et al. Validation of a risk score identifying patients with acute pulmonary embolism, who are at low risk of clinical adverse outcome. Thromb Haemost 2004 91 : 1232 6.
25. Aujesky D, Obrosky DS, Stone RA et al. A prediction rule to identify low-risk patients with pulmonary embolism. Arch Intern Med 2006 166 : 169 75.
26. ten Wolde M, Sohne M, Quak E, Mac Gillavry MR, Buller HR. Prognostic value of echocardiographically assessed right ventricular dysfunction in patients with pulmonary embolism. Arch Intern Med 2004 164 : 1685 9.
27. Gibson NS, Sohne M, Buller HR. Prognostic value of echocardiography and spiral computed tomography in patients with pulmonary embolism. Curr Opin Pulm Med 2005 11 : 380 4.
28. van der Meer RW, Pattynama PM, van Strijen MJ et al. Right ventricular dysfunction and pulmonary obstruction index at helical CT: prediction of clinical outcome during 3-month follow-up in patients with acute pulmonary embolism. Radiology 2005 235 : 798 803.
29. Sohne M, Ten Wolde M, Buller HR. Biomarkers in pulmonary embolism. Curr Opin Cardiol 2004 19 : 558 62.
30. Quinlan DJ, McQuillan A, Eikelboom JW. Low-molecular-weight heparin compared with intravenous unfractionated heparin for treatment of pulmonary embolism: a meta-analysis of randomized, controlled trials. Ann Intern Med 2004 140 : 175 83.
31. Wan S, Quinlan DJ, Agnelli G, Eikelboom JW. Thrombolysis compared with heparin for the initial treatment of pulmonary embolism. A meta-analysis of randomized controlled trials. Circulation 2004 110 : 744 9.