Hormetic prevention of molecular damage during cellular aging of human skin fibroblasts and keratinocytes

Annals of the New York Academy of Sciences

Volumn 1100, Issue , 2007, Pages 424-430

  Rattan, Suresh I S ^a   Ali, Rehab E ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Heat shock; Hormesis; Hormetin; Na K ATPase; Sodium pump; Stress

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALCOHOL; CURCUMIN; GLUCOSE; GLYOXAL; HYDROGEN PEROXIDE; PROTEASOME; STRESS ACTIVATED PROTEIN KINASE; HEAT SHOCK PROTEIN;

BIOACCUMULATION; BIOCHEMISTRY; CELL AGING; CELL CULTURE; CELL DAMAGE; CELL DIFFERENTIATION; CELL FUNCTION; CELL GROWTH; CELL STRESS; CELL SURVIVAL; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GLYCOSIDATION; HEAT STRESS; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; MOLECULAR BIOLOGY; PROTEIN DEGRADATION; SKIN FIBROBLAST; TEMPERATURE DEPENDENCE; ULTRAVIOLET B RADIATION; ANIMAL; APOPTOSIS; CYTOLOGY; FIBROBLAST; HEAT; LONGEVITY; METABOLISM; REVIEW; TEMPERATURE;

ANIMALS; APOPTOSIS; CELL AGING; CELLS, CULTURED; CURCUMIN; FIBROBLASTS; HEAT; HEAT-SHOCK PROTEINS; HUMANS; KERATINOCYTES; LONGEVITY; NA(+)-K(+)-EXCHANGING ATPASE; PROTEASOME ENDOPEPTIDASE COMPLEX; TEMPERATURE;

EID: 34249660963     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1395.047     Document Type: Conference Paper

References (20)

1. RATTAN, S.I.S. 2006. Theories of biological aging: genes, proteins and free radicals. Free Radic Res. 40: 1230-1238.
2. RATTAN, S.I.S. 2004. Aging, anti-aging, and hormesis. Mech. Ageing Dev. 125: 285-289.
3. RATTAN, S.I.S. 2005. Principles and practice of hormesis as an aging intervention. In Aging Interventions and Therapies. S.I.S. Rattan, Ed.: 365-378. World Scientific Publishers. Singapore.
4. ANSON, R.M. et al. 2003. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie restriction. Proc. Natl. Acad. Sci. USA 100: 6216-6220.
5. MARTIN, B., M.P. MATTSON & S. MAUDSLEY. 2006. Caloric restriction and intermittent fasting: two potential diets for successful aging. Ageing Res. Rev. 5: 332-353.
6. ALI, R.E. & S.I.S. RATTAN. 2006. Curcumin's biphasic hormetic response on proteasome activity and heat shock protein synthesis in human keratinocytes. Ann. N. Y. Acad. Sci. 1067: 394-399.
7. VERBEKE, P. et al. 2001. Heat shock response and ageing: mechanisms and applications. Cell Biol. Int. 25: 845-857.
8. STOLZING, A., S. SETHE & A. SCUTT. 2006. Stressed stem cells: temperature response in aged mesenchymal stem cells. Stem Cells Develop. 15: 478-487.
9. RATTAN, S.I.S. 2004. Aging intervention, prevention, and therapy through hormesis. J. Gerontol. Biol. Sci. 59A: 705-709.
10. RATTAN, S.I.S. 2005. Anti-ageing strategies: prevention or therapy? EMBO Reports 6: S25-S29.
11. NIELSEN, E.R., Y. ESKILDSEN-HELMOND & S.I.S. RATTAN. 2006. MAP-kinases and heat shock-induced hormesis in human fibroblasts during serial passaging in vitro. Ann. N. Y. Acad. Sci. 1067: 343-348.
12. NøRGAARD, R., M. KASSEM & S.I.S. RATTAN. 2006. Heat shock-induced enhancement of osteoblastic differentiation of hTERT-immortalized mesenchymal stem cells. Ann. N. Y. Acad. Sci. 1067: 443-447.
13. BERGE, U., P. KRISTENSEN & S.I.S. RATTAN. 2006. Kinetin-induced differentiation of normal human keratinocytes undergoing aging in vitro. Ann. N. Y. Acad. Sci. 1067: 332-336.
14. NORSGAARD, H., B.F.C. CLARK & S.I.S. RATTAN. 1996. Distinction between differentiation and senescence and the absence of increased apoptosis in human keratinocytes undergoing cellular aging in vitro. Exp. Gerontol. 31: 563-570.
15. FONAGER, J. et al. 2002. Mild stress-induced stimulation of heat shock protein synthesis and improved functional ability of human fibroblasts undergoing aging in vitro. Exp. Gerontol. 37: 1223-1238.
16. BEEDHOLM, R., B.F.C. CLARK & S.I.S. RATTAN. 2004. Mild heat stress stimulates proteasome and its 11S activator in human fibroblasts undergoing aging in vitro. Cell Stress Chaperones 9: 49-57.
17. XIE, Z. et al. 1989. Determination of total (Na++K+)-ATPase activity of isolated or cultured cells. Anal. Biochem. 183: 215-219.
18. RATTAN, S.I.S. & L. SODAGAM. 2005. Gerontomodulatory and youth-preserving effects of zeatin on human skin fibroblasts undergoing aging in vitro. Rejuv. Res. 8: 46-57.
19. MASORO, E.J. 2006. Dietary restriction-induced life extension: a broadly based biological phenomenon. Biogerontology 7: 153-155.
20. HERCUS, M.J., V. LOESCHCKE & S.I.S. RATTAN. 2003. Lifespan extension of Drosophila melanogaster through hormesis by repeated mild heat stress. Biogerontology 4: 149-156.