Collagen matrix deposition is dramatically enhanced in vitro when crowded with charged macromolecules: The biological relevance of the excluded volume effect

FEBS Letters

Volumn 581, Issue 14, 2007, Pages 2709-2714

  Lareu, Ricky R ^a,b   Subramhanya, Karthik Harve ^a   Peng, Yanxian ^a   Benny, Paula ^a   Chen, Clarice ^a   Wang, Zhibo ^a   Rajagopalan, Raj ^c   Raghunath, Michael ^a,b  

^a Faculty of Engineering   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Collagen deposition; Excluded volume effect; Extracellular matrix; Macromolecular crowding; Procollagen C proteinase

Indexed keywords

COLLAGEN; PROCOLLAGEN C PROTEINASE;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; MACROMOLECULE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

BLOTTING, WESTERN; CELL LINE; CELL SIZE; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; EXTRACELLULAR MATRIX; FIBROBLASTS; HUMANS; MACROMOLECULAR SUBSTANCES; MATRIX METALLOPROTEINASE 2; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR WEIGHT;

EID: 34249654626     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.05.020     Document Type: Article

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