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Volumn 2, Issue 1, 2007, Pages 51-58

Standard versus dose-intensified chemotherapy with sequential reinfusion of hematopoietic progenitor cells in small cell lung cancer patients with favorable prognosis

Author keywords

Chemotherapy; Filgrastim; Hematopoietic progenitor cells; ICE; Small cell lung cancer

Indexed keywords

CARBOPLATIN; ETOPOSIDE; IFOSFAMIDE; MESNA; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; ANTINEOPLASTIC AGENT;

EID: 34249652554     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0b013e31802baf9d     Document Type: Article
Times cited : (22)

References (43)
  • 1
    • 0026500785 scopus 로고
    • Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: A phase III trial of the Southeastern Cancer Study Group
    • Roth BJ, Johnson DH, Einhorn LH, et al. Randomized study of cyclophosphamide, doxorubicin, and vincristine versus etoposide and cisplatin versus alternation of these two regimens in extensive small-cell lung cancer: a phase III trial of the Southeastern Cancer Study Group. J Clin Oncol 1992;10:282-291.
    • (1992) J Clin Oncol , vol.10 , pp. 282-291
    • Roth, B.J.1    Johnson, D.H.2    Einhorn, L.H.3
  • 2
    • 0029067170 scopus 로고
    • Phase II study of ifosfamide, carboplatin, and oral etoposide chemotherapy for extensive-disease small-cell lung cancer: An Eastern Cooperative Oncology Group pilot study
    • Wolff AC, Ettinger DS, Neuberg D, et al. Phase II study of ifosfamide, carboplatin, and oral etoposide chemotherapy for extensive-disease small-cell lung cancer: an Eastern Cooperative Oncology Group pilot study. J Clin Oncol 1995;13:1615-1622.
    • (1995) J Clin Oncol , vol.13 , pp. 1615-1622
    • Wolff, A.C.1    Ettinger, D.S.2    Neuberg, D.3
  • 3
    • 0021971351 scopus 로고
    • Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up
    • Johnson BE, Ihde DC, Bunn PA, et al. Patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation. Data on potential cures, chronic toxicities, and late relapses after a five- to eleven-year follow-up. Ann Intern Med 1985;103:430-438.
    • (1985) Ann Intern Med , vol.103 , pp. 430-438
    • Johnson, B.E.1    Ihde, D.C.2    Bunn, P.A.3
  • 4
    • 0024411271 scopus 로고
    • Carboplatin, ifosfamide and etoposide with mid-course vincristine and thoracic radiotherapy for 'limited' stage small cell carcinoma of the bronchus
    • Thatcher N, Lind M, Stout R, et al. Carboplatin, ifosfamide and etoposide with mid-course vincristine and thoracic radiotherapy for 'limited' stage small cell carcinoma of the bronchus. Br J Cancer 1989;60:98-101.
    • (1989) Br J Cancer , vol.60 , pp. 98-101
    • Thatcher, N.1    Lind, M.2    Stout, R.3
  • 5
    • 0032414054 scopus 로고    scopus 로고
    • Modified ice study: A phase II study of an intensive, modified ICE regimen (ifosfamide, carboplatin and etoposide) in patients with better prognosis, small cell lung cancer
    • Shevlin PM, Muers MF, Peake MD, et al. Modified ice study: a phase II study of an intensive, modified ICE regimen (ifosfamide, carboplatin and etoposide) in patients with better prognosis, small cell lung cancer. Lung Cancer 1998;21:115-126.
    • (1998) Lung Cancer , vol.21 , pp. 115-126
    • Shevlin, P.M.1    Muers, M.F.2    Peake, M.D.3
  • 6
    • 0029164627 scopus 로고
    • Chemotherapy with vincristine/ifosfamide/carboplatin/etoposide in small cell lung cancer
    • Lorigan P, Lee SM, Betticher D, et al. Chemotherapy with vincristine/ifosfamide/carboplatin/etoposide in small cell lung cancer. Semin Oncol 1995;22:32-41.
    • (1995) Semin Oncol , vol.22 , pp. 32-41
    • Lorigan, P.1    Lee, S.M.2    Betticher, D.3
  • 7
    • 0033901542 scopus 로고    scopus 로고
    • Cisplatin, ifosfamide, oral etoposide, and concurrent accelerated hyperfractionated thoracic radiation for patients with limited small-cell lung carcinoma: Results of radiation therapy oncology group trial 93-12
    • Glisson B, Scott C, Komaki R, et al. Cisplatin, ifosfamide, oral etoposide, and concurrent accelerated hyperfractionated thoracic radiation for patients with limited small-cell lung carcinoma: results of radiation therapy oncology group trial 93-12. J Clin Oncol 2000;18:2990-2995.
    • (2000) J Clin Oncol , vol.18 , pp. 2990-2995
    • Glisson, B.1    Scott, C.2    Komaki, R.3
  • 8
    • 0033611522 scopus 로고    scopus 로고
    • Twice-daily compared with oncedaily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide
    • Turrisi AT, Kim K, Blum R, et al. Twice-daily compared with oncedaily thoracic radiotherapy in limited small-cell lung cancer treated concurrently with cisplatin and etoposide. N Engl J Med 1999;340:265-271.
    • (1999) N Engl J Med , vol.340 , pp. 265-271
    • Turrisi, A.T.1    Kim, K.2    Blum, R.3
  • 9
    • 0037099617 scopus 로고    scopus 로고
    • Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: Results of the Japan Clinical Oncology Group Study 9104
    • Takada M, Fukuoka M, Kawahara M, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with cisplatin and etoposide for limited-stage small-cell lung cancer: results of the Japan Clinical Oncology Group Study 9104. J Clin Oncol 2002;20:3054-3060.
    • (2002) J Clin Oncol , vol.20 , pp. 3054-3060
    • Takada, M.1    Fukuoka, M.2    Kawahara, M.3
  • 10
    • 0027231433 scopus 로고
    • Maintenance chemotherapy in small-cell lung cancer: Long-term results of a randomized trial. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group
    • Giaccone G, Dalesio O, McVie GJ, et al. Maintenance chemotherapy in small-cell lung cancer: long-term results of a randomized trial. European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group. J Clin Oncol 1993;11:1230-1240.
    • (1993) J Clin Oncol , vol.11 , pp. 1230-1240
    • Giaccone, G.1    Dalesio, O.2    McVie, G.J.3
  • 11
    • 0028149937 scopus 로고
    • Prospective randomized comparison of high-dose and standard-dose etoposide and cisplatin chemotherapy in patients with extensive-stage small-cell lung cancer
    • Ihde DC, Mulshine JL, Kramer BS, et al. Prospective randomized comparison of high-dose and standard-dose etoposide and cisplatin chemotherapy in patients with extensive-stage small-cell lung cancer. J Clin Oncol 1994;12:2022-2034.
    • (1994) J Clin Oncol , vol.12 , pp. 2022-2034
    • Ihde, D.C.1    Mulshine, J.L.2    Kramer, B.S.3
  • 12
    • 0024563045 scopus 로고
    • Duration of chemotherapy in small cell lung cancer: A Cancer Research Campaign trial
    • Spiro SG, Souhami RL, Geddes DM, et al. Duration of chemotherapy in small cell lung cancer: a Cancer Research Campaign trial. Br J Cancer 1989;59:578-583.
    • (1989) Br J Cancer , vol.59 , pp. 578-583
    • Spiro, S.G.1    Souhami, R.L.2    Geddes, D.M.3
  • 13
    • 0024337158 scopus 로고
    • A simple outpatient treatment with oral ifosfamide and oral etoposide for patients with small cell lung cancer (SCLC)
    • Cerny T, Lind M, Thatcher N, et al. A simple outpatient treatment with oral ifosfamide and oral etoposide for patients with small cell lung cancer (SCLC). Br J Cancer 1989;60:258-261.
    • (1989) Br J Cancer , vol.60 , pp. 258-261
    • Cerny, T.1    Lind, M.2    Thatcher, N.3
  • 14
    • 0028830167 scopus 로고
    • Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood
    • Pettengell R, Woll PJ, Thatcher N, et al. Multicyclic, dose-intensive chemotherapy supported by sequential reinfusion of hematopoietic progenitors in whole blood. J Clin Oncol 1995;13:148-156.
    • (1995) J Clin Oncol , vol.13 , pp. 148-156
    • Pettengell, R.1    Woll, P.J.2    Thatcher, N.3
  • 15
    • 34547443395 scopus 로고    scopus 로고
    • Buyse M, Staquet M, Sylvester Ret al. Cancer Clinical Trials Methods and Practice. Oxford, UK: Oxford University Press, 2005.
    • Buyse M, Staquet M, Sylvester Ret al. Cancer Clinical Trials Methods and Practice. Oxford, UK: Oxford University Press, 2005.
  • 16
    • 34547473064 scopus 로고    scopus 로고
    • NCI-CTC. National Cancer Institute Cancer Therapy Evaluation Program Common Toxicity Criteria, version 2.0. Available at:, Accessed 1997
    • NCI-CTC. National Cancer Institute Cancer Therapy Evaluation Program Common Toxicity Criteria, version 2.0. Available at: http://ctep. cancer.gov/reporting/ctc.html. Accessed 1997.
  • 17
    • 33845382806 scopus 로고
    • Nonparametric estimation for incomplete observation
    • Kaplan EL, Meier P. Nonparametric estimation for incomplete observation. J Am Stat Assos 1958;53:457-481.
    • (1958) J Am Stat Assos , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 18
    • 0036788622 scopus 로고    scopus 로고
    • Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: A prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923
    • Ardizzoni A, Tjan-Heijnen VC, Postmus PE, et al. Standard versus intensified chemotherapy with granulocyte colony-stimulating factor support in small-cell lung cancer: a prospective European Organization for Research and Treatment of Cancer-Lung Cancer Group Phase III Trial-08923. J Clin Oncol 2002;20:3947-3955.
    • (2002) J Clin Oncol , vol.20 , pp. 3947-3955
    • Ardizzoni, A.1    Tjan-Heijnen, V.C.2    Postmus, P.E.3
  • 19
    • 0027521597 scopus 로고
    • Initial chemotherapeutic doses and survival in patients with limited small-cell lung cancer
    • Arriagada R, Le Chevalier T, Pignon JP, et al. Initial chemotherapeutic doses and survival in patients with limited small-cell lung cancer. N Engl J Med 1993;329:1848-1852.
    • (1993) N Engl J Med , vol.329 , pp. 1848-1852
    • Arriagada, R.1    Le Chevalier, T.2    Pignon, J.P.3
  • 20
    • 0021744793 scopus 로고
    • The importance of dose intensity in chemotherapy of metastatic breast cancer
    • Hryniuk W, Bush H. The importance of dose intensity in chemotherapy of metastatic breast cancer. J Clin Oncol 1984;2:1281-1288.
    • (1984) J Clin Oncol , vol.2 , pp. 1281-1288
    • Hryniuk, W.1    Bush, H.2
  • 21
    • 0027322192 scopus 로고
    • The impact of dose intensity of standard chemotherapy regimens in extensive stage small cell lung cancer
    • Sheehan RG, Balaban EP, Frenkel EP. The impact of dose intensity of standard chemotherapy regimens in extensive stage small cell lung cancer. Am J Clin Oncol 1993;16:250-255.
    • (1993) Am J Clin Oncol , vol.16 , pp. 250-255
    • Sheehan, R.G.1    Balaban, E.P.2    Frenkel, E.P.3
  • 22
    • 0036810184 scopus 로고    scopus 로고
    • An analysis of chemotherapy dose and dose-intensity in small-cell lung cancer: Lessons to be drawn
    • Tjan-Heijnen VC, Wagener DJ, Postmus PE. An analysis of chemotherapy dose and dose-intensity in small-cell lung cancer: lessons to be drawn. Ann Oncol 2002;13:1519-1530.
    • (2002) Ann Oncol , vol.13 , pp. 1519-1530
    • Tjan-Heijnen, V.C.1    Wagener, D.J.2    Postmus, P.E.3
  • 23
    • 0036875583 scopus 로고    scopus 로고
    • High-dose chemotherapy in small-cell lung cancer
    • Pasini F, Durante E, De Manzoni D, et al. High-dose chemotherapy in small-cell lung cancer. Anticancer Res 2002;22:3465-3472.
    • (2002) Anticancer Res , vol.22 , pp. 3465-3472
    • Pasini, F.1    Durante, E.2    De Manzoni, D.3
  • 24
    • 0027055377 scopus 로고
    • A phase II study of ifosfamide in combination with etoposide and cisplatin in the treatment of extensive small cell lung cancer
    • Evans WK, Stewart D, Logan D, et al. A phase II study of ifosfamide in combination with etoposide and cisplatin in the treatment of extensive small cell lung cancer. Semin Oncol 1992;19:51-56.
    • (1992) Semin Oncol , vol.19 , pp. 51-56
    • Evans, W.K.1    Stewart, D.2    Logan, D.3
  • 25
    • 0036786077 scopus 로고    scopus 로고
    • Outpatient intensive chemotherapy for small cell lung cancer: Five years experience of modified 'ICE' ifosfamide carboplatin and etoposide
    • Hand S, Baker J, Smith AP, et al. Outpatient intensive chemotherapy for small cell lung cancer: five years experience of modified 'ICE' ifosfamide carboplatin and etoposide. Clin Oncol (R Coll Radiol) 2002;14:367-371.
    • (2002) Clin Oncol (R Coll Radiol) , vol.14 , pp. 367-371
    • Hand, S.1    Baker, J.2    Smith, A.P.3
  • 26
    • 0025827446 scopus 로고
    • Intensive therapy for smallcell lung cancer using carboplatin alternating with cisplatin, ifosfamide, etoposide, mid-cycle vincristine, and radiotherapy
    • Prendiville J, Radford J, Thatcher N, et al. Intensive therapy for smallcell lung cancer using carboplatin alternating with cisplatin, ifosfamide, etoposide, mid-cycle vincristine, and radiotherapy. J Clin Oncol 1991;9:1446-1452.
    • (1991) J Clin Oncol , vol.9 , pp. 1446-1452
    • Prendiville, J.1    Radford, J.2    Thatcher, N.3
  • 27
    • 0027939569 scopus 로고
    • Intensive combined-modality therapy in small cell lung cancer
    • Thatcher N, Lorrigan P, Burt P, et al. Intensive combined-modality therapy in small cell lung cancer. Semin Oncol 1994;21:9-22.
    • (1994) Semin Oncol , vol.21 , pp. 9-22
    • Thatcher, N.1    Lorrigan, P.2    Burt, P.3
  • 28
    • 0027992901 scopus 로고
    • Direct comparison by limiting dilution analysis of long-term culture-initiating cells in human bone marrow, umbilical cord blood, and blood stem cells
    • Pettengell R, Luft T, Henschler R, et al. Direct comparison by limiting dilution analysis of long-term culture-initiating cells in human bone marrow, umbilical cord blood, and blood stem cells. Blood 1994;84:3653-3659.
    • (1994) Blood , vol.84 , pp. 3653-3659
    • Pettengell, R.1    Luft, T.2    Henschler, R.3
  • 29
    • 0028588681 scopus 로고
    • Viability of haemopoietic progenitors from whole blood, bone marrow and leukapheresis product: Effects of storage media, temperature and time
    • Pettengell R, Woll PJ, O'Connor DA, Dexter TM, Testa NG. Viability of haemopoietic progenitors from whole blood, bone marrow and leukapheresis product: effects of storage media, temperature and time. Bone Marrow Transplant 1994;14:703-709.
    • (1994) Bone Marrow Transplant , vol.14 , pp. 703-709
    • Pettengell, R.1    Woll, P.J.2    O'Connor, D.A.3    Dexter, T.M.4    Testa, N.G.5
  • 30
    • 0036276301 scopus 로고    scopus 로고
    • Autologous stem cell transplantation for small cell lung cancer
    • Rizzo JD, Elias AD, Stiff PJ, et al. Autologous stem cell transplantation for small cell lung cancer. Biol Blood Marrow Transplant 2002;8:273-280.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 273-280
    • Rizzo, J.D.1    Elias, A.D.2    Stiff, P.J.3
  • 31
    • 0024365557 scopus 로고
    • Intensive chemotherapy with autologous bone marrow transplantation for small-cell lung cancer
    • Souhami RL, Hajichristou HT, Miles DW, et al. Intensive chemotherapy with autologous bone marrow transplantation for small-cell lung cancer. Cancer Chemother Pharmacol 1989;24:321-325.
    • (1989) Cancer Chemother Pharmacol , vol.24 , pp. 321-325
    • Souhami, R.L.1    Hajichristou, H.T.2    Miles, D.W.3
  • 32
    • 0032946574 scopus 로고    scopus 로고
    • High-dose ifosfamide, carboplatin and etoposide with autologous peripheral blood progenitor cell transplantation for small-cell lung cancer
    • Bessho A, Ueoka H, Kiura K, et al. High-dose ifosfamide, carboplatin and etoposide with autologous peripheral blood progenitor cell transplantation for small-cell lung cancer. Anticancer Res 1999;19:693-698.
    • (1999) Anticancer Res , vol.19 , pp. 693-698
    • Bessho, A.1    Ueoka, H.2    Kiura, K.3
  • 33
    • 0036247773 scopus 로고    scopus 로고
    • Intensive chemotherapy with whole blood stem-cell support and concurrent chest radiotherapy in small cell lung cancer: A phase I/II trial
    • Calderoni A, von Briel C, Aebi S, et al. Intensive chemotherapy with whole blood stem-cell support and concurrent chest radiotherapy in small cell lung cancer: a phase I/II trial. Lung Cancer 2002;36:321-326.
    • (2002) Lung Cancer , vol.36 , pp. 321-326
    • Calderoni, A.1    von Briel, C.2    Aebi, S.3
  • 34
    • 0027946388 scopus 로고
    • High-dose ifosfamide/carboplatin/ etoposide with autologous hematopoietic stem cell support: Safety and future directions
    • Elias AD, Ayash LJ, Wheeler C, et al. High-dose ifosfamide/carboplatin/ etoposide with autologous hematopoietic stem cell support: safety and future directions. Semin Oncol 1994;21:83-85.
    • (1994) Semin Oncol , vol.21 , pp. 83-85
    • Elias, A.D.1    Ayash, L.J.2    Wheeler, C.3
  • 35
    • 0036066568 scopus 로고    scopus 로고
    • Dose-intensive therapy for extensive-stage small cell lung cancer and extrapulmonary small cell carcinoma: Long-term outcome
    • Elias AD, Skarin AT, Richardson P, et al. Dose-intensive therapy for extensive-stage small cell lung cancer and extrapulmonary small cell carcinoma: long-term outcome. Biol Blood Marrow Transplant 2002;8:326-333.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 326-333
    • Elias, A.D.1    Skarin, A.T.2    Richardson, P.3
  • 36
    • 0032703763 scopus 로고    scopus 로고
    • Multiple courses of high-dose ifosfamide, carboplatin, and etoposide with peripheral-blood progenitor cells and filgrastim for small-cell lung cancer: A feasibility study by the European Group for Blood and Marrow Transplantation
    • Leyvraz S, Perey L, Rosti G, et al. Multiple courses of high-dose ifosfamide, carboplatin, and etoposide with peripheral-blood progenitor cells and filgrastim for small-cell lung cancer: A feasibility study by the European Group for Blood and Marrow Transplantation. J Clin Oncol 1999;17:3531-3539.
    • (1999) J Clin Oncol , vol.17 , pp. 3531-3539
    • Leyvraz, S.1    Perey, L.2    Rosti, G.3
  • 37
    • 0036972013 scopus 로고    scopus 로고
    • Early tandem high-dose ifosfamide, carboplatin, etoposide therapy with stem cell rescue for smallcell lung cancer: Brief report on the results of a phase-I/II trial
    • Oelmann E, Thomas M, Serve H, et al. Early tandem high-dose ifosfamide, carboplatin, etoposide therapy with stem cell rescue for smallcell lung cancer: brief report on the results of a phase-I/II trial. Oncology 2002;63:248-253.
    • (2002) Oncology , vol.63 , pp. 248-253
    • Oelmann, E.1    Thomas, M.2    Serve, H.3
  • 38
    • 10244219869 scopus 로고    scopus 로고
    • Sequential high-dose ICE chemotherapy with circulating progenitor cells (CPC) in small cell lung cancer: An EBMT study
    • Perey L, Rosti G, Lange A, et al. Sequential high-dose ICE chemotherapy with circulating progenitor cells (CPC) in small cell lung cancer: an EBMT study. Bone Marrow Transplant 1996;18(suppl 1):S40-S43.
    • (1996) Bone Marrow Transplant , vol.18 , Issue.SUPPL. 1
    • Perey, L.1    Rosti, G.2    Lange, A.3
  • 39
    • 0035253367 scopus 로고    scopus 로고
    • Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: A randomized phase II trial in small-cell lung cancer patients
    • Woll PJ, Thatcher N, Lomax L, et al. Use of hematopoietic progenitors in whole blood to support dose-dense chemotherapy: a randomized phase II trial in small-cell lung cancer patients. J Clin Oncol 2001;19:712-719.
    • (2001) J Clin Oncol , vol.19 , pp. 712-719
    • Woll, P.J.1    Thatcher, N.2    Lomax, L.3
  • 40
    • 17444451710 scopus 로고    scopus 로고
    • A phase I dose escalation study of multicyclic, dose-intensive chemotherapy with peripheral blood stem cell support for small cell lung cancer
    • Takahashi M, Yoshizawa H, Tanaka H, et al. A phase I dose escalation study of multicyclic, dose-intensive chemotherapy with peripheral blood stem cell support for small cell lung cancer. Bone Marrow Transplant 2000;25:5-11.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 5-11
    • Takahashi, M.1    Yoshizawa, H.2    Tanaka, H.3
  • 41
    • 0028925666 scopus 로고
    • Can cytotoxic dose-intensity be increased by using granulocyte colony-stimulating factor? A randomized controlled trial of lenograstim in small-cell lung cancer
    • Woll PJ, Hodgetts J, Lomax L, et al. Can cytotoxic dose-intensity be increased by using granulocyte colony-stimulating factor? A randomized controlled trial of lenograstim in small-cell lung cancer. J Clin Oncol 1995;13:652-659.
    • (1995) J Clin Oncol , vol.13 , pp. 652-659
    • Woll, P.J.1    Hodgetts, J.2    Lomax, L.3
  • 42
    • 18344374561 scopus 로고    scopus 로고
    • Randomized phase III trial of dose-dense chemotherapy supported by whole-blood hematopoietic progenitors in better-prognosis small-cell lung cancer
    • Lorigan P, Woll PJ, O'Brien MER, et al. Randomized phase III trial of dose-dense chemotherapy supported by whole-blood hematopoietic progenitors in better-prognosis small-cell lung cancer. J Natl Cancer Inst 2005;97:666-674.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 666-674
    • Lorigan, P.1    Woll, P.J.2    O'Brien, M.E.R.3
  • 43
    • 0031917065 scopus 로고    scopus 로고
    • Effects of granulocytemacrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: A prospective randomized study of 300 patients
    • Steward WP, Von Pawel J, Gatzemeier U, et al. Effects of granulocytemacrophage colony-stimulating factor and dose intensification of V-ICE chemotherapy in small-cell lung cancer: a prospective randomized study of 300 patients. J Clin Oncol 1998;16:642-650.
    • (1998) J Clin Oncol , vol.16 , pp. 642-650
    • Steward, W.P.1    Von Pawel, J.2    Gatzemeier, U.3


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