Capturing and amplifying impurities from purified recombinant monoclonal antibodies via peptide library beads: A proteomic study

Proteomics

Volumn 7, Issue 10, 2007, Pages 1624-1633

  Antonioli, Paolo ^a   Fortis, Fréderic ^b   Guerrier, Luc ^b   Rinalducci, Sara ^c   Zolla, Lello ^c   Righetti, Pier Giorgio ^a   Boschetti, Egisto ^b  

^a POLITECNICO DI MILANO   (Italy)

^b CEA SACLAY   (France)

^c UNIVERSITY OF TUSCIA   (Italy)

Author keywords

Host cell proteins; Impurity analysis; Ligand library; Mass spectrometry; Peptide ligands

Indexed keywords

ALBUMIN; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY; RECOMBINANT DNA; TRANSFERRIN;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; CULTURE MEDIUM; MASS SPECTROMETRY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEOMICS;

ANIMALS; ANTIBODIES, MONOCLONAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEOME; RECOMBINANT PROTEINS;

EID: 34249651243     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200600778     Document Type: Conference Paper

References (21)

1. Garnick, R. L., Solli, N. J., Papa, P. A., Anal. Chem. 1988, 60, 2546-2557.
2. Hewitt, L., McDonnell, J. M., Methods Mol. Biol. 2004, 278, 1-16.
3. Murasugi, A., Tohma-Aiba, Y., Protein Expr. Purif. 2003, 27, 244-252.
4. Lubiniecki, A. S., Cytotechnology 1998, 28, 139-145.
5. Bhopale, G. M., Nanda, R. K., Curr. Sci. 2005, 89, 614-622.
6. States, D. J., Omenn, G. S., Blackwell, T. W., Fermin, D. et al., Nat. Biotechol. 2006, 24, 333-338.
7. Anderson, N. L., Anderson, N. G., Mol. Cell. Proteomics 2002, 1, 845-867.
8. Thulasiraman, V., Lin, S., Gheorghiu, L., Lathrop, J. et al., Electrophoresis 2005, 26, 3561-3571.
9. Righetti, P. G., Castagna, A., Antonioli, P., Boschetti, E., Electrophoresis 2005, 26, 297-319.
10. Righetti, P. G., Castagna, A., Antonucci, F., Piubelli, C. et al., Clin. Chim. Acta 2005, 357, 123-139.
11. Righetti, P. G., Boschetti, E., Lomas, L., Citterio, A., Proteomics 2006, 6, 3980-3992.
12. Castagna, A., Cecconi, D., Sennels, L., Rappsilber, J. et al., J. Proteome Res. 2005, 4, 1917-1930.
13. Sennels, L., Salek, M., Lomas, L., Boschetti, E. et al., Mol. Cell. Proteomics 2007, in press.
14. Fortis, F., Guerrier, L., Righetti, P. G., Antonioli, P., Boschetti, E., Electrophoresis 2006, 27, 3018-3027.
15. Voute, N., Fortis, F., Guerrier, L., Girot, P., Int. J. Biol. C 2000, 5, 49-65.
16. Boschetti, E., Guerrier, L., Int. J. BioChromatogr. 2002, 6, 269-283.
17. Boschetti, E., TRENDS Biotechol. 2002, 20, 333-337.
18. Hamdan, M., Righetti, P. G., Proteomics Today: Protein Assessment and Biomarkers Using Mass Spectrometry, 2-D Electrophoresis and Microarray Technology, Wiley-VCH, Hoboken 2005, pp. 362-365.
19. Shevchenko, A., Wilm, M., Vorm, O., Mann, M., Anal. Chem. 1996, 68, 850-858.
20. Pietrogrande, M. C., Marchetti, N., Dondi, F., Righetti, P. G., Electrophoresis 2002, 23, 283-291.
21. Campostrini, N., Areces, L. B., Rappsilber, J., Pietrogrande, M. C. et al., Proteomics 2005, 5, 2385-2395.