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Volumn 3, Issue 1, 2007, Pages 3-11

Role of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy)

Author keywords

Antiepileptic drug; Lennox Gastaut syndrome; Pediatrics; Rufinamide

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CINROMIDE; CYTOCHROME P450; FELBAMATE; GAMMA BUTYROLACTONE GAMMA CARBONYLHISTIDYLPROLINAMIDE CITRATE; LAMOTRIGINE; MESTRANOL PLUS NORETHISTERONE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PLACEBO; PRIMIDONE; RUFINAMIDE; TOPIRAMATE; TRIAZOLE DERIVATIVE; VALPROIC ACID;

EID: 34249333895     PISSN: 11766328     EISSN: None     Source Type: Journal    
DOI: 10.2147/nedt.2007.3.1.3     Document Type: Article
Times cited : (28)

References (43)
  • 1
    • 0041374023 scopus 로고    scopus 로고
    • Increased QT dispersion in epileptic children
    • Akalin F, Tirtir A, Yilmaz Y. 2003. Increased QT dispersion in epileptic children. Acta Paediatr, 92:916-20.
    • (2003) Acta Paediatr , vol.92 , pp. 916-920
    • Akalin, F.1    Tirtir, A.2    Yilmaz, Y.3
  • 2
    • 0024312464 scopus 로고
    • Double-blind, placebo-controlled evaluation of cinromide in patients with the Lennox-Gastaut syndrome. The Group for the Evaluation of Cinromide in the Lennox-Gastaut syndrome
    • Anonymous
    • Anonymous. 1989. Double-blind, placebo-controlled evaluation of cinromide in patients with the Lennox-Gastaut syndrome. The Group for the Evaluation of Cinromide in the Lennox-Gastaut syndrome. Epilepsia, 30:422-9.
    • (1989) Epilepsia , vol.30 , pp. 422-429
  • 3
    • 0027530628 scopus 로고
    • Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). The Felbamate Study Group in Lennox Gastaut syndrome
    • Anonymous
    • Anonymous. 1993. Efficacy of felbamate in childhood epileptic encephalopathy (Lennox-Gastaut syndrome). The Felbamate Study Group in Lennox Gastaut syndrome. N Engl J Med, 328:29-33.
    • (1993) N Engl J Med , vol.328 , pp. 29-33
  • 4
    • 0030297333 scopus 로고    scopus 로고
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 1996. Progress report on new antiepileptic drugs: a summary of the third Eilat conference. Epilepsy Res, 25:299-319.
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 1996. Progress report on new antiepileptic drugs: a summary of the third Eilat conference. Epilepsy Res, 25:299-319.
  • 5
    • 0033061573 scopus 로고    scopus 로고
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 1999. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference. Epilepsy Res, 34(1):1-41.
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 1999. Progress report on new antiepileptic drugs: a summary of the fourth Eilat conference. Epilepsy Res, 34(1):1-41.
  • 6
    • 0035200133 scopus 로고    scopus 로고
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 2001. Progress report on new antiepileptic drugs: a summary of the fifth Eilat conference. Epilepsy Res, 43:11-58.
    • Bialer M, Johannessen SI, Kupferberg HJ, et al. 2001. Progress report on new antiepileptic drugs: a summary of the fifth Eilat conference. Epilepsy Res, 43:11-58.
  • 8
    • 0347475737 scopus 로고
    • Pharmacokinetics of a new anticonvulsant. (CGP 33101) in epileptic male patients and healthy male subjects after single ascending oral doses of 400-1200 mg
    • Brunner LA, Harrigan EP, John VA, Powell ML. 1994. Pharmacokinetics of a new anticonvulsant. (CGP 33101) in epileptic male patients and healthy male subjects after single ascending oral doses of 400-1200 mg. Am J Ther, 1:215-20.
    • (1994) Am J Ther , vol.1 , pp. 215-220
    • Brunner, L.A.1    Harrigan, E.P.2    John, V.A.3    Powell, M.L.4
  • 9
    • 0031959729 scopus 로고    scopus 로고
    • The influence of food on the disposition of the antiepileptic nifinamide in healthy volunteers
    • Cardot JM, Lecaillon JB, Czendlik C, et al. 1998. The influence of food on the disposition of the antiepileptic nifinamide in healthy volunteers. Biopharm Drug Dispos, 19:259-62.
    • (1998) Biopharm Drug Dispos , vol.19 , pp. 259-262
    • Cardot, J.M.1    Lecaillon, J.B.2    Czendlik, C.3
  • 10
    • 0006757668 scopus 로고    scopus 로고
    • A pharmacokinetic evaluation of rufinamide in elderly and younger subjects [abstract]
    • 2.110
    • Chang SW, Choi L, Karoplchyk MA. 1998. A pharmacokinetic evaluation of rufinamide in elderly and younger subjects [abstract]. Epilepsia, 39(Suppl 6):59 (2.110).
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 59
    • Chang, S.W.1    Choi, L.2    Karoplchyk, M.A.3
  • 11
    • 0029566317 scopus 로고
    • Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension
    • Cheung WK, Kianifard F, Wong A, et al. 1995. Intra- and inter-subject variabilities of CGP 33101 after replicate single oral doses of two 200-mg tablets and 400-mg suspension. Pharm Res, 12:1878-82.
    • (1995) Pharm Res , vol.12 , pp. 1878-1882
    • Cheung, W.K.1    Kianifard, F.2    Wong, A.3
  • 12
    • 34249287288 scopus 로고    scopus 로고
    • Current problems in pharmacovigilance
    • Committee on Safety of Medicines, online, Accessed 21 June 2006. URL
    • Committee on Safety of Medicines. 1996. Current problems in pharmacovigilance. Reminder Lamotrigine (Lamictal) and serious skin reactions [online]. Accessed 21 June 2006. URL: http://www.mhra.gov.uk/ home/groups/pl-p/documents/publication/con2023237.pdf.
    • (1996) Reminder Lamotrigine (Lamictal) and serious skin reactions
  • 13
    • 34249336671 scopus 로고    scopus 로고
    • Critchley D, Fuseau E, Perdomo C, Arroyo S. 2005. Pharmacokinetic and pharmacodynamic parameters of adjunctive rufinamide in patients with Lennox-Gastaut Syndrome [abstract]. Epilepsia, 46(Suppl 7):2.351.
    • Critchley D, Fuseau E, Perdomo C, Arroyo S. 2005. Pharmacokinetic and pharmacodynamic parameters of adjunctive rufinamide in patients with Lennox-Gastaut Syndrome [abstract]. Epilepsia, 46(Suppl 7):2.351.
  • 14
    • 34249333776 scopus 로고    scopus 로고
    • Dulac O, Engel J. Lennox-Gastaut Syndrome. 2003. Report of the International League against Epilepsy (updated 23 August 2003) [online]. Accessed 21 June 2006. URL: http://www.ilae-epilepsy.org/ctf/ lennox_gastaut.html.
    • Dulac O, Engel J. Lennox-Gastaut Syndrome. 2003. Report of the International League against Epilepsy (updated 23 August 2003) [online]. Accessed 21 June 2006. URL: http://www.ilae-epilepsy.org/ctf/ lennox_gastaut.html.
  • 15
    • 33745599006 scopus 로고    scopus 로고
    • Eisai Co Ltd, online, Accessed 21 June 2006. URL
    • Eisai Co Ltd. 2005. Annual Report 2005 [online]. Accessed 21 June 2006. URL: http://www.eisai.co.jp/pdf/eannual/epdf200504an.pdf
    • (2005) Annual Report 2005
  • 16
    • 34249309529 scopus 로고
    • FDA document T94-46, online, 27 September 1994. Accessed 21 June 2006. URL
    • FDA document T94-46. 1994. Felbatol update [online]. 27 September 1994. Accessed 21 June 2006. URL: http://www.fda.gov/bbs/topics/ANSWERS/ ANS00605.html.
    • (1994) Felbatol update
  • 17
    • 34249318673 scopus 로고    scopus 로고
    • FDA 'Dear Doctor' letter. 1997. [online]. Accessed 21 June 2006. URL: http://www.fda.gov/medwatch/safety/1997/lamict.htm.
    • FDA 'Dear Doctor' letter. 1997. [online]. Accessed 21 June 2006. URL: http://www.fda.gov/medwatch/safety/1997/lamict.htm.
  • 18
    • 34249303721 scopus 로고    scopus 로고
    • FDA 'Dear Doctor' letter. 2003. [online]. Accessed 21 June 2006. URL: http://www.fda.gov/medwatch/SAFETY/2003/topamax.htm.
    • FDA 'Dear Doctor' letter. 2003. [online]. Accessed 21 June 2006. URL: http://www.fda.gov/medwatch/SAFETY/2003/topamax.htm.
  • 19
    • 11144353969 scopus 로고    scopus 로고
    • Efficacy and tolerability of the new antiepiteptic drugs II: Treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society [online]
    • Accessed 21 June 2006. URL
    • French JA, Kanner AM, Bautista J, et al. 2004. Efficacy and tolerability of the new antiepiteptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society [online]. Neurology, 62(8):1261-73. Accessed 21 June 2006. URL: http://www.neurology.org/cgi/content/full/62/ 8/1261.
    • (2004) Neurology , vol.62 , Issue.8 , pp. 1261-1273
    • French, J.A.1    Kanner, A.M.2    Bautista, J.3
  • 20
    • 34249288943 scopus 로고    scopus 로고
    • Fuseau E, Critchley D, Perdomo C, Arroyo S. 2005. Population pharmacokinetic drug-drug interaction analyses of rufinamide studies in patients with epilepsy [abstract]. Epilepsia, 46(Suppl 8):2.356.
    • Fuseau E, Critchley D, Perdomo C, Arroyo S. 2005. Population pharmacokinetic drug-drug interaction analyses of rufinamide studies in patients with epilepsy [abstract]. Epilepsia, 46(Suppl 8):2.356.
  • 21
    • 34249277721 scopus 로고    scopus 로고
    • Glauser TA, Kluger G, Sachdeo R, et al. 2005a. Efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut Syndrome (LGS): A multicenter, randomized, double-blind, placebo-controlled parallel trial [abstract]. Neurology, 64(10):1862 (LBS.001).
    • Glauser TA, Kluger G, Sachdeo R, et al. 2005a. Efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut Syndrome (LGS): A multicenter, randomized, double-blind, placebo-controlled parallel trial [abstract]. Neurology, 64(10):1862 (LBS.001).
  • 22
    • 33748541467 scopus 로고    scopus 로고
    • Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome [abstract]
    • Glauser T, Kluger G, Sachdeo R, et al. 2005b. Open-label extension study of the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut syndrome [abstract]. Epilepsia, 46(Suppl 6):408(1356).
    • (2005) Epilepsia , vol.46 , Issue.1356 SUPPL. 6 , pp. 408
    • Glauser, T.1    Kluger, G.2    Sachdeo, R.3
  • 23
    • 32144432641 scopus 로고    scopus 로고
    • Epilepsy in children
    • Guerrini R. 2006. Epilepsy in children. Lancet, 367(9509):499-524.
    • (2006) Lancet , vol.367 , Issue.9509 , pp. 499-524
    • Guerrini, R.1
  • 24
    • 84885134015 scopus 로고    scopus 로고
    • Hancock E, Cross H. 2003. Treatment of Lennox-Gastaut syndrome. Cochrane Database Syst Rev, 3:CD003277.
    • Hancock E, Cross H. 2003. Treatment of Lennox-Gastaut syndrome. Cochrane Database Syst Rev, 3:CD003277.
  • 25
    • 0024344113 scopus 로고
    • Clinical study of oral administration of DN-1417, a TRH analog, in patients with intractable epilepsy
    • Inanaga K, Kumashiro H, Fukyama Y, et al. 1989. Clinical study of oral administration of DN-1417, a TRH analog, in patients with intractable epilepsy. Epilepsia, 30:438-45.
    • (1989) Epilepsia , vol.30 , pp. 438-445
    • Inanaga, K.1    Kumashiro, H.2    Fukyama, Y.3
  • 26
    • 34249287630 scopus 로고    scopus 로고
    • Janssen-Cilag Ltd. 2006. Topamax® [online]. High Wycombe, UK. 20 January 2006. Accessed 21 June 2006. URL: http://emc.medicines.org.uk/ emc/assets/c/html/displayDocPrinterFriendly.asp?documentid=6768.
    • Janssen-Cilag Ltd. 2006. Topamax® [online]. High Wycombe, UK. 20 January 2006. Accessed 21 June 2006. URL: http://emc.medicines.org.uk/ emc/assets/c/html/displayDocPrinterFriendly.asp?documentid=6768.
  • 27
    • 0006756610 scopus 로고    scopus 로고
    • Evaluation of rufinamide (CGP 33101), a novel anticonvulsant, for potential drug interactions in vitro [abstract]
    • 1.96
    • Kapeghian JC, Madan A, Parkinson A, et al. 1996. Evaluation of rufinamide (CGP 33101), a novel anticonvulsant, for potential drug interactions in vitro [abstract]. Epilepsia, 37(Suppl 5):26 (1.96).
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 5 , pp. 26
    • Kapeghian, J.C.1    Madan, A.2    Parkinson, A.3
  • 28
    • 34249281224 scopus 로고    scopus 로고
    • Short-term and long-term efficacy and safety of rufinamide as adjunctive therapy in patients with inadequately controlled Lennox-Gastaut syndrome. Poster
    • presented at the, Helsinki, Finland, 2-6 July
    • Kluger G, Glauser T, Sachdeo R. et al. 2006. Short-term and long-term efficacy and safety of rufinamide as adjunctive therapy in patients with inadequately controlled Lennox-Gastaut syndrome. Poster presented at the 7th European Congress on Epileptology, Helsinki, Finland, 2-6 July 2006.
    • (2006) 7th European Congress on Epileptology
    • Kluger, G.1    Glauser, T.2    Sachdeo, R.3
  • 29
    • 34249330206 scopus 로고    scopus 로고
    • Short-term and long-term safety of rufinamide in patients with epilepsy [abstract, 46(Suppl 7):2.363
    • Krauss GL, Perdomo C, Arroyo S. 2005. Short-term and long-term safety of rufinamide in patients with epilepsy [abstract]. Epilepsia, 46(Suppl 7):2.363.
    • (2005) Epilepsia
    • Krauss, G.L.1    Perdomo, C.2    Arroyo, S.3
  • 30
    • 34249283336 scopus 로고    scopus 로고
    • Levy RH, Manson RH, Meldrurn BS, Perucca E eds, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p
    • Levy RH, Manson RH, Meldrurn BS, Perucca E (eds). 2002a. In Antiepileptic drugs, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p 906-12.
    • (2002) Antiepileptic drugs , pp. 906-912
  • 31
    • 0004203209 scopus 로고    scopus 로고
    • Levy RH, Manson RH, Meldrum BS, Perucca E eds, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p
    • Levy RH, Manson RH, Meldrum BS, Perucca E (eds). 2002b. In Antiepileptic drugs, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p 206-14.
    • (2002) Antiepileptic drugs , pp. 206-214
  • 32
    • 34249291031 scopus 로고    scopus 로고
    • Levy RH, Manson RH, Meldrum BS, Perucca E eds, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p
    • Levy RH, Manson RH, Meldrum BS, Perucca E (eds). 2002c. In Antiepileptic drugs, 5th ed. Philadelphia: Lippincott Williams and Wilkins. p 760-764.
    • (2002) Antiepileptic drugs , pp. 760-764
  • 33
    • 34249340762 scopus 로고    scopus 로고
    • The Influence of rufinamide on sodium currents and action potential firing in rodent neurons [abstract, 46(Suppl 7):3.062
    • McLean MJ, Schmutz M, Pozza M, et al. 2005. The Influence of rufinamide on sodium currents and action potential firing in rodent neurons [abstract]. Epilepsia, 46(Suppl 7):3.062.
    • (2005) Epilepsia
    • McLean, M.J.1    Schmutz, M.2    Pozza, M.3
  • 35
    • 1642498346 scopus 로고    scopus 로고
    • Lennox-Gastaut syndrome (childhood epileptic encephalopathy)
    • Markand ON. 2003. Lennox-Gastaut syndrome (childhood epileptic encephalopathy). J Clin Neurophysiol, 20:42641.
    • (2003) J Clin Neurophysiol , vol.20 , pp. 42641
    • Markand, O.N.1
  • 36
    • 0031453973 scopus 로고    scopus 로고
    • Lamotrigine for generalised seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group
    • Motte J, Trevathan E, Arvidsson JF, et al. 1997. Lamotrigine for generalised seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group. N Engl J Med, 337:1807-12.
    • (1997) N Engl J Med , vol.337 , pp. 1807-1812
    • Motte, J.1    Trevathan, E.2    Arvidsson, J.F.3
  • 37
    • 1642498350 scopus 로고    scopus 로고
    • Epileptic encephalopathies: A brief overview
    • Nabbout R, Dulac O. 2003. Epileptic encephalopathies: a brief overview. J Clin Neurophysiol, 20:393-7.
    • (2003) J Clin Neurophysiol , vol.20 , pp. 393-397
    • Nabbout, R.1    Dulac, O.2
  • 38
    • 0000489497 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy [abstract]
    • 5.081
    • Sachdeo RC, Rosenfeld WE, Choi L, et al. 1998. Pharmacokinetics and safety of adjunctive rufinamide therapy in pediatric patients with epilepsy [abstract]. Epilepsia, 39(Suppl 6):166-7 (5.081).
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 166-167
    • Sachdeo, R.C.1    Rosenfeld, W.E.2    Choi, L.3
  • 39
    • 0032976081 scopus 로고    scopus 로고
    • A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group
    • Sachdeo RC, Glauser TA, Ritter F, et al. 1999. A double-blind, randomized trial of topiramate in Lennox-Gastaut syndrome. Topiramate YL Study Group. Neurology, 52:1882-7.
    • (1999) Neurology , vol.52 , pp. 1882-1887
    • Sachdeo, R.C.1    Glauser, T.A.2    Ritter, F.3
  • 40
    • 0034098323 scopus 로고    scopus 로고
    • A risk-benefit assessment of therapies for Lennox-Gastaut syndrome
    • Schmidt D, Bourgeois B. 2000. A risk-benefit assessment of therapies for Lennox-Gastaut syndrome. Drug Saf, 22:467-77.
    • (2000) Drug Saf , vol.22 , pp. 467-477
    • Schmidt, D.1    Bourgeois, B.2
  • 41
    • 0006492632 scopus 로고    scopus 로고
    • Single center, open-label, multiple-dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/35 in healthy women [abstract]
    • 2.111
    • Svendsen KD, Choi L, Chen BL, et al. 1998. Single center, open-label, multiple-dose pharmacokinetic trial investigating the effect of rufinamide administration on Ortho-Novum 1/35 in healthy women [abstract]. Epilepsia, 39(Suppl 6):59 (2.111).
    • (1998) Epilepsia , vol.39 , Issue.SUPPL. 6 , pp. 59
    • Svendsen, K.D.1    Choi, L.2    Chen, B.L.3
  • 42
    • 0000029301 scopus 로고    scopus 로고
    • Metabolism of the new anticonvulsive trial drug rulinamide (CGP 33101) in healthy male volunteers [abstract]
    • 6.60
    • Waldmeier F, Gschwind H-P, Rouan M-C, et al. 1996. Metabolism of the new anticonvulsive trial drug rulinamide (CGP 33101) in healthy male volunteers [abstract]. Epilepsia, 37(Suppl 5):167 (6.60).
    • (1996) Epilepsia , vol.37 , Issue.SUPPL. 5 , pp. 167
    • Waldmeier, F.1    Gschwind, H.-P.2    Rouan, M.-C.3
  • 43
    • 34249322960 scopus 로고    scopus 로고
    • The anticonvulsant profile and tolerability of rufinamide in mice and rats [abstract, 46(Suppl 7):3.088
    • White, S, Schmutz, M, Pozza, M, et al. 2005. The anticonvulsant profile and tolerability of rufinamide in mice and rats [abstract), Epilepsia, 46(Suppl 7):3.088.
    • (2005) Epilepsia
    • White, S.1    Schmutz, M.2    Pozza, M.3


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