Brain phenylalanine measurement in patients with phenylketonuria: A serious diagnostic method or just reading tea leaves?

Molecular Genetics and Metabolism

Volumn 91, Issue 3, 2007, Pages 297-298

  Bik Multanowski, Miroslaw ^a   Pietrzyk, Jacek J ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

PHENYLALANINE;

ADOLESCENT; ADULT; AMINO ACID BLOOD LEVEL; APPARATUS; BRAIN LEVEL; CALCULATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; HUMAN; IMAGE ANALYSIS; LETTER; MAJOR CLINICAL STUDY; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHENYLKETONURIA; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCHOOL CHILD; SIGNAL DETECTION;

ADOLESCENT; ADULT; BRAIN; CHILD; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; PHENYLALANINE; PHENYLKETONURIAS; WATER;

EID: 34249321248     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2007.03.008     Document Type: Letter

References (4)

1. Moats R.A., Koch R., Moseley K., Guldberg P., Guttler F., Boles R.G., and Nelson M.D. Brain phenylalanine concentration in the management of adults with phenylketonuria. J. Inherit. Metab. Dis. 23 (2000) 7-14
2. Möller H.E., Weglage J., Bick U., Wiedermann D., Feldmann R., and Ullrich K. Brain imaging and proton magnetic resonance spectroscopy in patients with phenylketonuria. Pediatrics 112 (2003) 1580-1583
3. Rupp A., Kreis R., Zschocke J., Slotboom J., Boesch C., Rating D., and Pietz J. Variability of blood-brain ratios of phenylalanine in typical patients with phenylketonuria. J. Cereb. Blood Flow Metab. 21 (2001) 276-284
4. Möller H.E., Ullrich K., and Weglage J. In vivo proton magnetic resonance spectroscopy in phenylketonuria. Eur. J. Pediatr. 159 (2000) S121-S125