Insulin-like growth factor-II regulates the 12-lipoxygenase gene expression and promotes cell proliferation in human keratinocytes via the extracellular regulatory kinase and phosphatidylinositol 3-kinase pathways

International Journal of Biochemistry and Cell Biology

Volumn 39, Issue 6, 2007, Pages 1248-1259

  Yoo, Hyun ^a   Kim, Su Jin ^a   Kim, Younghwa ^a   Lee, Hyangkyu ^a   Kim, Tae Yoon ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

12 hydroxyeicosatetraenoic acid; 12 Lipoxygenase; Extracellular signaling regulated kinase; Insulin like growth factor II; Phosphatidylinositol 3 kinase

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; DNA; HYDROXYICOSATETRAENOIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; DNA SYNTHESIS; ENZYME ACTIVITY; ENZYME INDUCTION; EPIDERMIS HYPERPLASIA; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; MITOGENESIS; MOUSE; NONHUMAN; PARACRINE SIGNALING; PATHOGENESIS; PROTEIN EXPRESSION; PSORIASIS; SIGNAL TRANSDUCTION; UPREGULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 12-HYDROXY-5,8,10,14-EICOSATETRAENOIC ACID; ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL LINE; CELL LINE, TRANSFORMED; CELL PROLIFERATION; CELL SURVIVAL; CHROMONES; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION; HUMANS; INSULIN-LIKE GROWTH FACTOR II; KERATINOCYTES; MICE; MICE, INBRED HRS; MORPHOLINES; PROTO-ONCOGENE PROTEINS C-FOS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SKIN;

MUS;

EID: 34249303782     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.04.009     Document Type: Article

References (40)

1. Arora J.K., Lysz T.W., and Zelenka P.S. A role for 12(S)-HETE in the response of human lens epithelial cells to epidermal growth factor and insulin. Investigative Ophthalmology & Visual Science 37 (1996) 1411-1418
2. Barr R.M., Wong E., Mallet A.I., Olins L.A., and Greaves M.W. The analysis of arachidonic acid metabolites in normal, uninvolved and lesional psoriatic skin. Prostaglandins 28 (1984) 57-65
3. Baserga R., Hongo A., Rubini M., Prisco M., and Valentinis B. The IGF-I receptor in cell growth, transformation and apoptosis. Biochimica et biophysica acta 1332 (1997) F105-F126
4. Bonnekoh B., Wevers A., Geisil J., Rasokat H., and Mahrle G. Antiproliferative potential of zidovudine in human keratinocytes cultures. Journal of American Academy of Dermatology 25 (1991) 483-490
5. Chen B.K., and Chang W.C. Overexpression of c-Fos enhances the transcription of human arachidonate 12-lipoxygenase in A431 cells. Biochemical and Biophysical Research Communications 261 (1999) 848-852
6. Daughaday W.H., and Rotwein P. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocrine Reviews 10 (1989) 68-91
7. De La Brassinne M.F., and Couteux-Dumont C.M. Tritiated thymidine labelling of epidermis in pustular psoriasis. Archives of Dermatology 106 (1972) 768
8. Ding X.Z., Iversen P., Cluck M.W., Knezetic J.A., and Adrian T.E. Lipoxygenase inhibitors abolish proliferation of human pancreatic cancer cells. Biochemical and Biophysical Research Communications 261 (1999) 218-223
9. Ding X.Z., Kuszynski C.A., El-Metwally T.H., and Adrian T.E. Lipoxygenase inhibition induced apoptosis, morphological changes, and carbonic anhydrase expression in human pancreatic cancer cells. Biochemical and Biophysical Research Communications 266 (1999) 392-399
10. Duffill M., Wright N., and Shuster S. The cell proliferation kinetics of psoriasis examined by three in vivo techniques. The British Journal of Dermatology 94 (1976) 355-362
11. Fry L., and Mcminn R.M. Observations on mitosis in psoriatic epidermis. The British Journal of Dermatology 82 (1970) 19-22
12. Honn K.V., Tang D.G., Gao X., Butovich I.A., Liu B., Timar J., et al. 12-lipoxygenases and 12(S)-HETE: Role in cancer metastasis. Cancer Metastasis Reviews 13 (1994) 365-396
13. Ikai K. Psoriasis and the arachidonic acid cascade. Journal of Dermatological Science 21 (1999) 135-146
14. Kim H.J., and Kim T.Y. IGF-II mediated cox-2 gene expression in human keratinocytes through extracellular signal-regulated kinase pathway. The Journal of Investigative Dermatology 123 (2004) 547-555
15. Kim H.J., and Kim T.Y. Regulation of vascular endothelial growth factor expression by insulin-like growth factor-II in human keratinocytes, differential involvement of mitogen-activated protein kinases and feedback inhibition of protein kinase C. The British Journal of Dermatology 152 (2005) 418-425
16. Krane J.F., Gottlieb A.B., Carter D.M., and Krueger J.G. The insulin-like growth factor I receptor is overexpressed in psoriatic epidermis, but is differentially regulated from the epidermal growth factor receptor. The Journal of Experimental Medicine 175 (1992) 1081-1090
17. Kwon Y.W., Kwon K.S., Moon H.E., Park J.A., Choi K.S., Kim Y.S., et al. Insulin-like growth factor-II regulates the expression of vascular endothelial growth factor by the human keratinocyte cell line HaCaT. The Journal of Investigative Dermatology 123 (2004) 152-158
18. Lehmann W.D. Regio- and stereochemistry of the dioxygenation reaction catalyzed by (S)-type lipoxygenases or by the cyclooxygenase activity of prostaglandin H synthases. Free Radical Biology & Medicine 16 (1994) 241-253
19. Liu Y.W., Arakawa T., Yamamoto S., and Chang W.C. Transcriptional activation of human 12-lipoxygenase gene promoter is mediated through Sp1 consensus sites in A431 cells. The Biochemical Journal 324 Pt 1 (1997) 133-140
20. Liu X.H., Connolly J.M., and Rose D.P. The 12-lipoxygenase gene-transfected MCF-7 human breast cancer cell line exhibits estrogen-independent, but estrogen and omega-6 fatty acid-stimulated proliferation in vitro, and enhanced growth in athymic nude mice. Cancer Letters 109 (1996) 223-230
21. Liu Y.W., Asaoka Y., Suzuki H., Yoshimoto T., Yamamoto S., and Chang W.C. Induction of 12-lipoxygenase expression by epidermal growth factor is mediated by protein kinase C in A431 cells. The Journal of Pharmacology and Experimental Therapeutics 271 (1994) 567-573
22. Lysz T.W., Arora J.K., Lin C., and Zelenka P.S. 12(S)-hydroxyeicosatetraenoic acid regulates DNA synthesis and protooncogene expression induced by epidermal growth factor and insulin in rat lens epithelium. Cell Growth & Differentiation 5 (1994) 1069-1076
23. Merriman H.L., La Tour D., Linkhart T.A., Mohan S., Baylink D.J., and Strong D.D. Insulin-like growth factor-I and insulin-like growth factor-II induce c-fos in mouse osteoblastic cells. Calcified Tissue International 46 (1990) 258-262
24. Mildner M., Weninger W., Trautinger F., Ban J., and Tschachler E. UVA and UVB radiation differentially regulate vascular endothelial growth factor expression in keratinocyte-derived cell lines and in human keratinocytes. Photochemistry and Photobiology 70 (1999) 674-679
25. Moghal N., and Sternberg P.W. Multiple positive and negative regulators of signaling by the EGF-receptor. Current Opinion in Cell Biology 11 (1999) 190-196
26. Natarajan R., and Nadler J. Role of lipoxygenases in breast cancer. Frontiers in Bioscience 3 (1998) E81-E88
27. Neely E.K., Morhenn V.B., Hintz R.L., Wilson D.M., and Rosenfeld R.G. Insulin-like growth factors are mitogenic for human keratinocytes and a squamous cell carcinoma. The Journal of Investigative Dermatology 96 (1991) 104-110
28. Nickoloff B.J. The immunologic and genetic basis of psoriasis. Archives of Dermatology 135 (1999) 1104-1110
29. Nie D., Che M., Grignon D., Tang K., and Honn K.V. Role of eicosanoids in prostate cancer progression. Cancer Metastasis Reviews 20 (2001) 195-206
30. Nie D., Hillman G.G., Geddes T., Tang K., Pierson C., Grignon D.J., et al. Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth. Cancer Research 58 (1998) 4047-4051
31. Nie D., and Honn K.V. Cyclooxygenase, lipoxygenase and tumor angiogenesis. Cellular and Molecular Life Sciences 59 (2002) 799-807
32. Nie D., Krishnamoorthy S., Jin R., Tang K., Chen Y., Qiao Y., et al. Mechanisms regulating tumor angiogenesis by 12-lipoxygenase in prostate cancer cells. The Journal of Biological Chemistry 281 (2006) 18601-18609
33. Rice R.L., Tang D.G., Haddad M., Honn K.V., and Taylor J.D. 12(S)-hydroxyeicosatetraenoic acid increases the actin microfilament content in B16a melanoma cells: a protein kinase-dependent process. International Journal of Cancer 77 (1998) 271-278
34. Storckenfeldt L., Schofield P.N., and Engstrom W. Stimulatory effect of insulin-like growth factor II on DNA synthesis in the human embryonic cornea. Cell Biology International Reports 15 (1991) 1217-1223
35. Timar J., Raso E., Honn K.V., and Hagmann W. 12-lipoxygenase expression in human melanoma cell lines. Advances in Experimental Medicine and Biology 469 (1999) 617-622
36. Weinstein G.D., and Frost P. Abnormal cell proliferation in psoriasis. The Journal of Investigative Dermatology 50 (1968) 254-259
37. Wraight C.J., Murashita M.M., Russo V.C., and Werther G.A. A keratinocyte cell line synthesizes a predominant insulin-like growth factor-binding protein (IGFBP-3) that modulates insulin-like growth factor-I action. The Journal of Investigative Dermatology 103 (1994) 627-631
38. Wraight C.J., and Werther G.A. Insulin-like growth factor-I and epidermal growth factor regulate insulin-like growth factor binding protein-3 (IGFBP-3) in the human keratinocyte cell line HaCaT. The Journal of Investigative Dermatology 105 (1995) 602-607
39. Xu S., Cwyfan-Hughes S.C., Van Der Stappen J.W.J., Sansom J., Burton J.L., Donnelly M., et al. Altered insulin-like growth factor-II (IGF-II) level and IGF-binding protein-3 (IGFBP-3) protease activity in interstitial fluid taken from the skin lesion of psoriasis. The Journal of Investigative Dermatology 106 (1996) 109-112
40. Yoshimura R., Inoue K., Kawahito Y., Mitsuhashi M., Tsuchida K., Matsuyama M., et al. Expression of 12-lipoxygenase in human renal cell carcinoma and growth prevention by its inhibitor. International Journal of Molecular Medicine 13 (2004) 41-46