Remnant like particles may induce atherosclerosis via accelerating endothelial progenitor cells senescence

Medical Hypotheses

Volumn 69, Issue 2, 2007, Pages 293-296

  Pu, Da Rong ^a   Liu, Ling ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHYLOMICRON; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOCAL ADHESION KINASE; LIPOPROTEIN; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REMNANT LIKE PARTICLE; TELOMERASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL FUNCTION; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; ISCHEMIC HEART DISEASE; MONOCYTE; NEOVASCULARIZATION (PATHOLOGY); OXIDATIVE STRESS; PRIORITY JOURNAL; SENESCENCE; STEM CELL;

ATHEROSCLEROSIS; CELL AGING; CHOLESTEROL; ENDOTHELIUM, VASCULAR; HUMANS; LIPOPROTEINS; STEM CELLS; TRIGLYCERIDES;

EID: 34249295245     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2006.11.046     Document Type: Article

References (30)

1. Jorn Op den Buijs, Mark Musters, et al. Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening. Am J Physiol Heart Circ Physiol 2004;287(6):H2651-8.
2. Jonathan M., Hill M.R.C.P., et al. Circulating endothelial progenitor cells, vascular function, and cardiovascular risk. N Engl J Med 348 7 (2003) 593-600
3. Caroline S.-L., Lothar R., et al. Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events. Circulation 111 (2005) 2981-2987
4. Khakoo A.Y., and Finkel T. Endothelial progenitor cells. Annu Rev Med 56 (2005) 79-101
5. Skora J., Biegus J., et al. Molecular basics of angiogenesis. Postepy Hig Med Dosw 60 (2006) 410-415
6. Zhu J., Wang X., et al. Reduced number and activity of circulating endothelial progenitor cells from patients with hyperhomocysteinemia. Arch Med Res 37 4 (2006) 484-489
7. Imanishi T., Hano T., et al. Oxidized low-density lipoprotein induces endothelial progenitor cell senescence, leading to cellular dysfunction. Clin Exp Pharmacol Physiol 31 7 (2004) 407-413
8. Zhu J.H., Chen J.Z., et al. Homocysteine accelerates senescence and reduces proliferation of endothelial progenitor cells. J Mol Cell Cardiol 40 5 (2006) 648-652
9. Isabelle G., Mary K., et al. Vascular smooth muscle cell senescence in atherosclerosis. Cardiovasc Res 72 1 (2006) 9-17 Epub June 6 2006
10. Imanishi T., Hano T., et al. Angiotensin II accelerates endothelial progenitor cell senescence through induction of oxidative stress. J Hypertens 23 1 (2005) 97-104
11. Akuzawa K., Nakano T., et al. Remnant-like particles-cholesterol (RLP-C) assay and its clinical application to lipid tests in a postprandial as well as fasting state. Rinsho Byori 43 11 (1995) 1159-1167
12. Ooi T.C., Cousins M., et al. Postprandial remnant-like lipoproteins in hypertriglyceridemia. J Clin Endocrinol Metab 86 7 (2001) 3134-3142
13. Oi K., Shimokawa H., et al. Postprandial increase in plasma concentrations of remnant-like particles: an independent risk factor for restenosis after percutaneous coronary intervention. J Cardiovasc Pharmacol 44 1 (2004) 66-73
14. Ishikawa T. Postprandial lipemia as an atherosclerotic risk factor and fat tolerance test. Nippon Rinsho 57 12 (1999) 2668-2672
15. Funada J., Sekiya M., et al. Postprandial elevation of remnant lipoprotein leads to endothelial dysfunction. Circ J 66 2 (2002) 127-132
16. op den Buijs J., van den Bosch P.P., et al. Mathematical modeling confirms the length-dependency of telomere shortening. Mech Ageing Dev 125 6 (2004) 437-444
17. Mariuca V., Kristin B., et al. Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res 87 (2000) 540
18. Imanishi T., Hano T., et al. Estrogen reduces angiotensin II-induced acceleration of senescence in endothelial progenitor cells. Hypertens Res 28 3 (2005) 263-271
19. Furumoto K., Inoue E., et al. Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress. Life Sci 63 11 (1998) 935-948
20. Reiske H.R., Zhao J., et al. Analysis of FAK-associated signaling pathways in the regulation of cell cycle progression. FEBS Lett 486 3 (2000) 275-280
21. Breitschopf K., Zeiher A.M., et al. Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism. FEBS Lett 493 1 (2001) 21-25
22. Smogorzewska A., and de Lange T. Regulation of telomerase by telomeric proteins. Annu Rev Biochem 73 (2004) 177-208
23. Tsuji N., and Watanabe N. Telomerase. Rinsho Byori 123 Suppl. (2002) 137-141
24. Kawauchi K., Ihjima K., et al. IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells. J Immunol 174 9 (2005) 5261-5269
25. Haendeler J., Hoffmann J., et al. Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation. FEBS Lett 536 1-3 (2003) 180-186
26. Le Boeuf F., Houle F., et al. Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities. J Biol Chem 279 37 (2004) 39175-39185 Epub July 6 2004
27. Koshida R., Rocic P., et al. Role of focal adhesion kinase in flow-induced dilation of coronary arterioles. Arterioscler Thromb Vasc Biol 25 12 (2005) 2548-2553 Epub September 2005
28. Doi H., Kugiyama K., et al. Remnant lipoproteins induce proatherothrombogenic molecules in endothelial cells through a redox-sensitive mechanism. Circulation 102 6 (2000) 670-676
29. Goulter A.B., Avella M.A., et al. Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries. Clin Sci (Lond) 103 5 (2002) 451-460
30. Kawakami A., Tanaka A., et al. Atorvastatin attenuates remnant lipoprotein-induced monocyte adhesion to vascular endothelium under flow condition. Circ Res 91 3 (2002) 263-271