Purification and identification of a 7.6-kDa protein in media conditioned by superinvasive cancer cells

Anticancer Research

Volumn 27, Issue 3 A, 2007, Pages 1309-1317

  Dowling, Paul ^a   Maurya, P ^a   Meleady, P ^a   Glynn, S A ^a   Dowd, A J ^a   Henry, M ^a   Clynes, M ^a  

^a DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

Drug resistant; IMAC; SELDI; Superinvasive; Transferrin

Indexed keywords

PACLITAXEL; TRANSFERRIN; TRANSFERRIN RECEPTOR;

CANCER CELL CULTURE; CANCER INVASION; CONFERENCE PAPER; CULTURE MEDIUM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; SURFACE ENHANCED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; UPREGULATION;

ADULT; BREAST NEOPLASMS; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PACLITAXEL; PEPTIDE FRAGMENTS; RECEPTORS, TRANSFERRIN; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFERRIN; TUMOR MARKERS, BIOLOGICAL;

EID: 34249294514     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (36)

1. Liang Y, McDonnell S and Clynes M: Examining the relationship between cancer invasion/metastasis and drug resistance. Curr Cancer Drug Targets 2: 257-277, 2002.
2. Cillo C, Dick JE, Ling V and Hill RP: Generation of drug-resistant variants in metastatic B16 mouse melanoma cell lines. Cancer Res 47: 2604-2608, 1987.
3. Cillo C, Ling V and Hill RP: Drug resistance in KHT fibrosarcoma cell lines with different metastatic ability. Int J Cancer 43: 107-111, 1989.
4. Giavazzi R, Miller L and Hart IR: Metastatic behavior of an adriamycin-resistant murine tumor. Cancer Res 43: 5081-5086, 1983.
5. Haga A, Nagase H, Kito H and Sato T: Invasive properties of cadmium-resistant human fibrosarcoma HT-1080 cells. Cancer Biochem Biophys 15: 275-284, 1997.
6. Staroselsky AN, Mahlin T and Savion N: Metastatic potential and multidrug resistance correlation in the B16 melanoma system. J Exp Ther Oncol 1: 251-259, 1996.
7. Liang Y, Meleady P, Cleary I, McDonnell S, Connolly L and Clynes M: Selection with melphalan or paclitaxel (Taxol) yields variants with different patterns of multidrug resistance, integrin expression and in vitro invasiveness. Eur J Cancer 37: 1041-1052, 2001.
8. Molinari A, Stringaro A, Gentile M, Colone M, Toccacieli L and Arancia G: Invasive properties of multidrug resistant human melanoma cells. Ital J Anat Embryol 110: 135-141, 2005.
9. Merchant M and Weinberger SR: Recent advancements in surface-enhanced laser desorption/ionization-time of flight-mass spectrometry. Electrophoresis 21: 1164-1177, 2000.
10. Li J, Zhang Z, Rosenzweig J, Wang YY and Chan DW: Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer. Clin Chem 48: 1296-1304, 2002.
11. Petricoin III EF, Ornstein DK, Paweletz CP, Ardekani A, Hackett PS, Hitt BA, Velassco A, Trucco C, Wiegand L, Wood K, Simone CB, Levine PJ, Linehan WM, Emmert-Buck MR, Steinberg SM, Kohn EC and Liotta LA: Serum proteomic patterns for detection of prostate cancer. J Natl Cancer Inst 94: 1576-1578, 2002.
12. Lawrie LC, Curran S, McLeod HL, Fothergill JE and Murray GI: Application of laser capture microdissection and proteomics in colon cancer. Mol Pathol 54: 253-258, 2001.
13. Chen AL, Soman KV, Rychahou PG, Luxon BA and Evers BM: Proteomic analysis of colonic myofibroblasts and effect on colon cancer cell proliferation. Surgery 138: 382-390, 2005.
14. Shiwa M, Nishimura Y, Wakatabe R, Fukawa A, Arikuni H, Ota H, Kato Y and Yamori T: Rapid discovery and identification of a tissue-specific tumor biomarker from 39 human cancer cell lines using the SELDI ProteinChip platform. Biochem Biophys Res Commun 309: 18-25, 2003.
15. Baggerly KA, Morris JS and Coombes KR: Reproducibility of SELDI-TOF protein patterns in serum: comparing datasets from different experiments. Bioinformatics 20: 777-785, 2004.
16. Diamandis EP: Analysis of serum proteomic patterns for early cancer diagnosis: drawing attention to potential problems. J Natl Cancer Inst 96: 353-356, 2004.
17. Check E: Proteomics and cancer: running before we can walk? Nature 429: 496-497, 2004.
18. Neuhoff N, Kaiser T, Wittke S, Krebs R, Pitt A, Burchard A, Sundmacher A, Schlegelberger B, Kolch W and Mischak H: Mass spectrometry for the detection of differentially expressed proteins: a comparison of surface-enhanced laser desorption/ionization and capillary electrophoresis/mass spectrometry. Rapid Commun Mass Spectrom 18: 149-156, 2004.
19. Glynn SA, Gammell P, Heenan M, O'Connor R, Liang Y, Keenan J and Clynes M: A new superinvasive in vitro phenotype induced by selection of human breast carcinoma cells with the chemotherapeutic drugs paclitaxel and doxorubicin. Br J Cancer 91: 1800-1807, 2004.
20. Cailleau R, Olive M and Cruciger QV: Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14: 911-915, 1978.
21. Ellison G, Klinowska T, Westwood RF, Docter E, French T and Fox JC: Further evidence to support the melanocytic origin of MDA-MB-435. Mol Pathol 55: 294-299, 2002.
22. Rae JM, Ramus SJ, Waltham M, Armes JE, Campbell IG, Clarke R, Barndt RJ, Johnson MD and Thompson EW: Common origins of MDA-MB-435 cells from various sources with those shown to have melanoma properties. Clin Exp Metastasis 21: 543-552, 2004.
23. Albini A, Melchiori A, Santi L, Liotta LA, Brown PD and Stetler-Stevenson WG: Tumor cell invasion inhibited by TIMP-2. J Natl Cancer Inst 83: 775-779, 1991.
24. Schevchenko A, Wilm M, Vorm O and Mann M: Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850-858, 1996.
25. Huebers HA and Finch CA: The physiology of transferrin and transferrin receptors. Physiol Rev 67: 520-582 1987.
26. Baker HM, Anderson BF and Naker EN: Dealing with iron: common structural principles in proteins that transport iron and heme. Proc Natl Acad Sci USA 100: 3579-3583, 2003.
27. Beutler E, Gelbart T, Lee P, Trevino R, Fernandez MA and Fairbanks VF: Molecular characterization of a case of atransferrinemia. Blood 96: 4071-4074, 2000.
28. r ∼ 90,000 cell surface transferrin receptor-related glycoprotein on murine B16 metastatic melanoma sublines selected for enhanced brain or ovary colonization. Cancer Res 50: 515-520, 1990.
29. Inoue T, Cavanaugh PG, Steck PA, Brünner N and Nicolson GL: Differences in transferrin response and numbers of transferrin receptors in rat and human mammary carcinoma lines of different metastatic potentials. J Cell Physiol 156: 212-217, 1993.
30. Zirvi KA: Development of serum-free media for the growth of human gastrointestinal adenocarcinoma xenografts as primary tissue cultures. J Cancer Res Clin Oncol 117: 515-518, 1991.
31. Fassl S, Leisser C, Huettenbrenner S, Maier S, Rosenberger G, Strasser S, Grusch M, Fuhrmann G, Leuhuber K, Polgar D, Stani J, Tichy B, Nowotny C and Krupitza G: Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNFalpha, FasL, TRAIL, or Myc. Oncogene 22: 8343-8355, 2003.
32. Yeoman LC, Wan CW and Zorbas MA: Transferrin and insulin enhance human colon tumor cell growth by differentiation class specific mechanisms. Oncol Res 8: 273-279, 1996.
33. Keer HN, Kozlowski JM, Tsai YC, Lee C, McEwan RN and Grayhack JT: Elevated transferrin receptor content in human prostate cancer cell lines assessed in vitro and in vivo. J Urol 143: 381-385, 1990.
34. Cheng PW: Receptor ligand-facilitated gene transfer: enhancement of liposome-mediated gene transfer and expression by transferrin. Hum Gene Ther 7: 275-282, 1996.
35. Elliott RL, Elliott MC, Wang F and Head JF: Breast carcinoma and the role of iron metabolism: a cytochemical, tissue culture, and ultrastructural study. Ann NY Acad Sci 698: 159-166, 1993.
36. Prutki M, Poljak-Blaz M, Jakopovic M, Tomas D, Stipancic I and Zarkovic N: Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer. Cancer Lett 238: 188-196, 2006.