Androgen receptors may act in a paracrine manner to regulate oesophageal adenocarcinoma growth

European Journal of Surgical Oncology

Volumn 33, Issue 5, 2007, Pages 561-568

  Awan, A K ^a,b   Iftikhar, S Y ^b   Morris, T M ^a   Clarke, P A ^a   Grabowska, A M ^a   Waraich, N ^a,b   Watson, S A ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b DERBYSHIRE ROYAL INFIRMARY   (United Kingdom)

Author keywords

Androgen receptor; Barrett's oesophagus; Fibroblast growth factor receptor 1 (FGFR 1); Fibroblast growth factor 8 isoform b (FGF 8b); Immunohistochemistry; Oesophageal cancer

Indexed keywords

ANDROGEN RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 8; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FOLLITROPIN; LUTEINIZING HORMONE; PROGESTERONE; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER INCIDENCE; CARCINOGENESIS; CONTROLLED STUDY; EPITHELIUM CELL; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS RESECTION; FEMALE; GENE EXPRESSION; GROWTH RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOASSAY; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PARACRINE SIGNALING; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SQUAMOUS CELL CARCINOMA; SQUAMOUS EPITHELIUM; TUMOR VOLUME;

ADENOCARCINOMA; ANIMALS; ESOPHAGEAL NEOPLASMS; FEMALE; FIBROBLAST GROWTH FACTOR 8; GENE EXPRESSION; GONADAL STEROID HORMONES; HUMANS; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; RECEPTORS, ANDROGEN; RECEPTORS, FIBROBLAST GROWTH FACTOR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 34249078345     PISSN: 07487983     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejso.2006.12.001     Document Type: Article

References (50)

1. Blot W.J., Devesa S.S., and Fraumeni Jr. J.F. Continuing climb in rates of esophageal adenocarcinoma: an update. JAMA 270 (1993) 1320
2. Sarr M.G., Hamilton S.R., Marrone G.C., and Cameron J.L. Barrett's esophagus: its prevalence and association with adenocarcinoma in patients with symptoms of gastroesophageal reflux. Am J Surg 149 (1985) 187-193
3. Winters Jr. C., Spurling T.J., Chobanian S.J., et al. Barrett's esophagus. A prevalent, occult complication of gastroesophageal reflux disease. Gastroenterology 92 (1987) 118-124
4. Kobayashi K. Effect of sex hormone on the experimental induction of esophageal cancer. Nippon Geka Gakkai Zasshi 86 (1985) 280-289
5. Koike K., Hinrichs S.H., Isselbacher K.J., and Jay G. Transgenic mouse model for human gastric carcinoma. Proc Natl Acad Sci USA 86 (1989) 5615-5619
6. Beato M., Herrlich P., and Schutz G. Steroid hormone receptors: many actors in search of a plot. Cell 83 (1995) 851-857
7. Harrison J.D., Watson S., and Morris D.L. The effect of sex hormones and tamoxifen on the growth of human gastric and colorectal cancer cell lines. Cancer 63 (1989) 2148-2151
8. Singh S., and Langman M.J. Oestrogen and colonic epithelial cell growth. Gut 37 (1995) 737-739
9. Tihan T., Harmon J.W., Wan X., et al. Evidence of androgen receptor expression in squamous and adenocarcinoma of the esophagus. Anticancer Res 21 (2001) 3107-3114
10. Yamashita Y., Hirai T., Mukaida H., et al. Detection of androgen receptors in human esophageal cancer. Jpn J Surg 19 (1989) 195-202
11. Wu C.W., Chi C.W., Chang T.J., Lui W.Y., and P'eng F.K. Sex hormone receptors in gastric cancer. Cancer 65 (1990) 1396-1400
12. Matsuoka H., Sugimachi K., Ueo H., Kuwano H., Nakano S., and Nakayama M. Sex hormone response of a newly established squamous cell line derived from clinical esophageal carcinoma. Cancer Res 47 (1987) 4134-4140
13. Ueo H., Matsuoka H., Sugimachi K., Kuwano H., Mori M., and Akiyoshi T. Inhibitory effects of estrogen on the growth of a human esophageal carcinoma cell line. Cancer Res 50 (1990) 7212-7215
14. Yamashita Y., Hirai T., Miyoshi Y., et al. Dependency on sex hormone in human esophageal cancer - measurement of the androgen receptor in resected specimens. Gan No Rinsho 33 (1987) 1303-1308
15. Fisher R.S., Roberts G.S., Grabowski C.J., and Cohen S. Inhibition of lower esophageal sphincter circular muscle by female sex hormones. Am J Physiol 234 (1978) E243-E247
16. Wald A., Van Thiel D.H., Hoechstetter L., et al. Gastrointestinal transit: the effect of the menstrual cycle. Gastroenterology 80 (1981) 1497-1500
17. Scott W.W., Menon M., and Walsh P.C. Hormonal therapy of prostatic cancer. Cancer 45 (1980) 1929-1936
18. Remenar E., Szamel I., Budai B., Gaudi I., Kasler M., and Gundy S. Serum levels of sex steroid and pituitary hormones in chronic alcoholics and head and neck cancer patients as compared to normal controls. Magy Onkol 46 (2002) 329-332
19. Fyssas I., Syrigos K.N., Konstandoulakis M.M., et al. Sex hormone levels in the serum of patients with pancreatic adenocarcinoma. Horm Metab Res 29 (1997) 115-118
20. Tiffin N., Suvarna S.K., Trudgill N.J., and Riley S.A. Sex hormone receptor immunohistochemistry staining in Barrett's oesophagus and adenocarcinoma. Histopathology 42 (2003) 95-96
21. Yamamoto K.R. Steroid receptor regulated transcription of specific genes and gene networks. Annu Rev Genet 19 (1985) 209-252
22. Carson-Jurica M.A., Schrader W.T., and O'Malley B.W. Steroid receptor family: structure and functions. Endocr Rev 11 (1990) 201-220
23. Tutton P.J., and Barkla D.H. Steroid hormones as regulators of the proliferative activity of normal and neoplastic intestinal epithelial cells. [review]. Anticancer Res 8 (1988) 451-456
24. Ignar-Trowbridge D.M., Nelson K.G., Bidwell M.C., et al. Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor. Proc Natl Acad Sci USA 89 (1992) 4658-4662
25. Yamanaka Y., Friess H., Buchler M., et al. Overexpression of acidic and basic fibroblast growth factors in human pancreatic cancer correlates with advanced tumor stage. Cancer Res 53 (1993) 5289-5296
26. Kobrin M.S., Yamanaka Y., Friess H., Lopez M.E., and Korc M. Aberrant expression of type I fibroblast growth factor receptor in human pancreatic adenocarcinomas. Cancer Res 53 (1993) 4741-4744
27. McLeskey S.W., Ding I.Y., Lippman M.E., and Kern F.G. MDA-MB-134 breast carcinoma cells overexpress fibroblast growth factor (FGF) receptors and are growth-inhibited by FGF ligands. Cancer Res 54 (1994) 523-530
28. Ornitz D.M., and Itoh N. Fibroblast growth factors. Genome Biol 2 (2001) [Reviews3005]
29. Johnson D.E., and Williams L.T. Structural and functional diversity in the FGF receptor multigene family. Adv Cancer Res 60 (1993) 1-41
30. Iida S., Katoh O., Tokunaga A., and Terada M. Expression of fibroblast growth factor gene family and its receptor gene family in the human upper gastrointestinal tract. Biochem Biophys Res Commun 199 (1994) 1113-1119
31. Tanigawa N., Amaya H., Matsumura M., and Shimomatsuya T. Correlation between expression of vascular endothelial growth factor and tumor vascularity, and patient outcome in human gastric carcinoma. J Clin Oncol 15 (1997) 826-832
32. Igarashi M., Dhar D.K., Kubota H., Yamamoto A., El-Assal O., and Nagasue N. The prognostic significance of microvessel density and thymidine phosphorylase expression in squamous cell carcinoma of the esophagus. Cancer 82 (1998) 1225-1232
33. Takebayashi Y., Natugoe S., Baba M., et al. Angiogenesis in esophageal squamous cell carcinoma. Oncol Rep 5 (1998) 401-404
34. Soslow R.A., Ying L., and Altorki N.K. Expression of acidic fibroblast growth factor in Barrett's esophagus and associated esophageal adenocarcinoma. J Thorac Cardiovasc Surg 114 (1997) 838-843
35. Lord R.V. Antireflux surgery for Barrett's oesophagus. ANZ J Surg 73 (2003) 234-236
36. Torres C., Wang H., Turner J., Shahsafaei A., and Odze R.D. Prognostic significance and effect of chemoradiotherapy on microvessel density (angiogenesis) in esophageal Barrett's esophagus-associated adenocarcinoma and squamous cell carcinoma. Hum Pathol 30 (1999) 753-758
37. Soslow R.A., Nabeya Y., Ying L., Blundell M., and Altorki N.K. Acidic fibroblast growth factor is progressively increased in the development of oesophageal glandular dysplasia and adenocarcinoma. Histopathology 35 (1999) 31-37
38. Finch P.W., Rubin J.S., Miki T., Ron D., and Aaronson S.A. Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth. Science 245 (1989) 752-755
39. Yan G., Fukabori Y., Nikolaropoulos S., Wang F., and McKeehan W.L. Heparin-binding keratinocyte growth factor is a candidate stromal-to-epithelial-cell andromedin. Mol Endocrinol 6 (1992) 2123-2128
40. Tanaka S., Ueo H., Mafune K., Mori M., Wands J.R., and Sugimachi K. A novel isoform of human fibroblast growth factor 8 is induced by androgens and associated with progression of esophageal carcinoma. Dig Dis Sci 46 (2001) 1016-1021
41. Wang Q., Stamp G.W., Powell S., et al. Correlation between androgen receptor expression and FGF8 mRNA levels in patients with prostate cancer and benign prostatic hypertrophy. J Clin Pathol 52 (1999) 29-34
42. Wu T.-T., Watanabe T., Heitmiller R., Zahurak M., Forastiere A.A., and Hamilton S.R. Genetic alterations in Barrett esophagus and adenocarcinomas of the esophagus and esophagogastric junction region. Am J Pathol 153 (1998) 287-294
43. Sugimachi K., Matsuoka H., Matsufuji H., Maekawa S., Kai H., and Okudaira Y. Survival rates of women with carcinoma of the esophagus exceed those of men. Surg Gynecol Obstet 164 (1987) 541-544
44. Badwe R.A., Patil P.K., Bhansali M.S., Mistry R.C., Juvekar R.R., and Desai P.B. Impact of age and sex on survival after curative resection for carcinoma of the esophagus. Cancer 74 (1994) 2425-2429
45. van der Burg B., de Groot R.P., Isbrucker L., Kruijer W., and de Laat S.W. Oestrogen directly stimulates growth factor signal transduction pathways in human breast cancer cells. J Steroid Biochem Mol Biol 40 (1991) 215-221
46. Sutherland R.L., Lee C.S., Feldman R.S., and Musgrove E.A. Regulation of breast cancer cell cycle progression by growth factors, steroids and steroid antagonists. J Steroid Biochem Mol Biol 41 (1992) 315-321
47. Beato M. Gene regulation by steroid hormones. Cell 56 (1989) 335-344
48. Sporn M.B., and Todaro G.J. Autocrine secretion and malignant transformation of cells. N Engl J Med 303 (1980) 878-880
49. Goustin A.S., Leof E.B., Shipley G.D., and Moses H.L. Growth factors and cancer. Cancer Res 46 (1986) 1015-1029
50. Ullrich A., and Schlessinger J. Signal transduction by receptors with tyrosine kinase activity. Cell 61 (1990) 203-212