Matrix Metalloprotease Activity Is Enhanced in the Compensated but Not in the Decompensated Phase of Pressure Overload Hypertrophy

American Journal of Hypertension

Volumn 20, Issue 6, 2007, Pages 663-669

  Tozzi, Rossana ^a   Palladini, Giuseppina ^a   Fallarini, Silvia ^a   Nano, Rosanna ^a   Gatti, Chiara ^a   Presotto, Cristina ^b   Schiavone, Antonio ^b   Micheletti, Rosella ^b   Ferrari, Patrizia ^b   Fogari, Roberto ^a   Perlini, Stefano ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b Prassis Sigma Tau Research Institute   (Italy)

Author keywords

Extracellular matrix; fibrosis; interstitial remodeling; matrix metalloproteinases; pressure overload hypertrophy

Indexed keywords

COLLAGEN; MATRIX METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA SURGERY; ARTICLE; BLOOD PRESSURE MEASUREMENT; CELL SIZE; COMPUTER ANALYSIS; CONTROLLED STUDY; DESCENDING AORTA; DIASTOLIC DYSFUNCTION; DOPPLER ECHOGRAPHY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GUINEA PIG; HEART FAILURE; HEART HEMODYNAMICS; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART LEFT VENTRICLE SIZE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; LUNG CONGESTION; LUNG WEIGHT; M MODE ECHOCARDIOGRAPHY; MALE; MANOMETRY; NONHUMAN; PRESSURE OVERLOAD HYPERTROPHY; PRIORITY JOURNAL; THORAX SURGERY; ZYMOGRAPHY;

ANIMALS; BLOOD PRESSURE; CARDIAC OUTPUT, LOW; CARDIOMYOPATHY, DILATED; COLLAGEN; DISEASE PROGRESSION; ECHOCARDIOGRAPHY; GUINEA PIGS; HEART VENTRICLES; HYPERTROPHY, LEFT VENTRICULAR; MALE; MATRIX METALLOPROTEINASES; TISSUE INHIBITOR OF METALLOPROTEINASES; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 34249076734     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.01.016     Document Type: Article

References (26)

1. Little W.C., and Applegate R.J. Congestive heart failure: systolic and diastolic function. J Cardiothor Vasc Anesth 7 (1993) 2-5
2. Pfeffer M.A., and Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation 81 (1990) 1161-1172
3. Spinale F.G. Matrix metalloproteinases: regulation and dysregulation in the failing heart. Circ Res 90 (2002) 520-530
4. Li-Saw-Hee F.L., Edmunds E., Blann A.D., Beevers D.G., and Lip G.Y. Matrix metalloproteinase-9 and tissue inhibitor metalloproteinase-1 levels in essential hypertension. Relationship to left ventricular mass and anti-hypertensive therapy. Int J Cardiol 75 (2000) 43-47
5. Spinale F.G., Coker M.L., Krombach S.R., Mukherjee R., Hallak H., Houck W.V., Clair M.J., Kribbs S.B., Johnson L.L., Peterson J.T., and Zile M.R. Matrix metalloproteinase inhibition during the development of congestive heart failure. Effects on left ventricular dimensions and function. Circ Res 85 (1999) 364-376
6. Dollery C.M., McEwan J.R., and Henney A.M. Matrix metalloproteinases and cardiovascular disease. Circ Res 77 (1995) 863-888
7. Borg T.K., and Burgen M.L. Holding it all together: organization and function(s) of the extracellular matrix in the heart. Heart Failure 8 (1993) 230-238
8. Weber K.T., Sun Y., Gurda E., Katwa L.C., Ratajska A., Cleutjens J.P., and Zhou G. Myocardial fibrosis in hypertensive heart disease: an overview of potential regulatory mechanisms. Eur Heart J 16 Suppl C (1995) 24-28
9. Spinale F.G., Tomita M., Zellner J.C., Cook J.C., Crawford F.A., and Zile M.R. Collagen remodelling and changes in LV function during development and recovery from supraventricular tachycardia. Am J Physiol 261 (1991) H308-H318
10. Randhawa A.K., and Singal P.K. Pressure overload-induced cardiac hypertrophy with and without dilation. J Am Coll Cardiol 20 (1992) 1569-1575
11. Chung E.S., Perlini S., Aurigemma G.P., Fenton R.A., Dobson Jr. J.G., and Meyer T.E. Effects of chronic adenosine uptake blockade on adrenergic responsiveness and left ventricular chamber function, in pressure overload hypertrophy in the rat. J Hypertens 16 (1998) 1813-1822
12. Meyer T.E., Chung E.S., Perlini S., Norton G.R., Woodwiss A.J., Corbor M., Fenton R.A., and Dobson Jr. J.G. Antiadrenergic effects of adenosine in pressure overload hypertrophy. Hypertension 37 (2001) 862-868
13. Sahn D.J., DeMaria A., Kisslo J., and Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 58 (1978) 1072-1083
14. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
15. Kleiner D., and Stetler-Stevenson W. Quantitative zymography: detection of picogram quantities of gelatinases. Anal Biochem 218 (1994) 325-329
16. Tyagi S., Campbell S., Reddy H., Tjahja E., and Voelker D. Matrix metalloproteinase activity expression in infarcted, noninfarcted and dilated cardiomiopathic human hearts. Mol Cell Biochem 155 (1996) 13-21
17. Galis Z., Sukhova G., Larck M., and Libby P. Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 94 (1994) 2493-2503
18. Tyagi S., Ratajska A., and Weber K. Myocardial matrix metalloproteinase(s): localization and activation. Mol Cell Biochem 126 (1993) 49-59
19. Garvey W. Modified elastic tissue-Masson trichrome stain. Stain Technol 59 (1984) 213-216
20. Lindsey M.L., Gannon J., Aikawa M., Schoen F.J., Rabkin E., Lopresti-Morrow L., Crawford J., Black S., Libby P., Mitchell P.G., and Lee R.T. Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation 105 (2002) 753-758
21. Rossi M.A. Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. J Hypertens 16 (1998) 1031-1041
22. Brilla C.G., and Weber K.T. Reactive and reparative myocardial fibrosis in arterial hypertension in the rat. Cardiovasc Res 26 (1992) 671-677
23. Nagatomo Y., Carabello B.A., Coker M.L., McDermott P.J., Nemoto S., Hamawaki M., and Spinale F.G. Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control. Am J Physiol 278 (2000) H151-H161
24. Gunja-Smith Z., Morales A.R., Romanelli R., and Woessner Jr. J.F. Remodelling of human myocardial collagen in idiopathic dilated cardiomyopathy: role of metalloproteinases and pyridinoline cross-links. Am J Pathol 148 (1996) 1639-1648
25. Iwanaga Y., Aoyama T., Kihara Y., Onozawa Y., Yoneda T., and Sasayama S. Excessive activation of matrix metalloproteinases coincides with left ventricular remodelling during transition from hypertrophy to heart failure in hypertensive rats. J Am Coll Cardiol 39 (2002) 1384-1391
26. Whittaker P., Kloner R.A., Boughner D.R., and Pickering J.G. Quantitative assessment of myocardial collagen with picrosirius red staining and circularly polarized light. Bas Res Cardiol 89 (1994) 397-410