Glycolipids with nonreducing end α-mannosyl residues that have the potential to activate invariant Vα19 NKT cells

FEBS Journal

Volumn 274, Issue 11, 2007, Pages 2921-2932

  Shimamura, Michio ^a,e   Huang, Yi Ying ^a   Okamoto, Naoki ^a   Watanabe, Yutaka ^b   Murakami, Yoshiko ^c   Kinoshita, Taroh ^c   Hirabayashi, Yoshio ^d   Murakata, Chikara ^d   Ito, Yukishige ^d   Ogawa, Tomoya ^d  

^a MITSUBISHI KAGAKU INSTITUTE OF LIFE SCIENCES   (Japan)

^b EHIME UNIVERSITY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d INST OF PHYS AND CHEMICAL RESEARCH   (Japan)

^e NONE   (Japan)

Author keywords

Glycolipid; Immune response; Invariant TCR ; MHC class Ib; NKT cell

Indexed keywords

ANTIGEN; CERAMIDE DERIVATIVE; GLYCOLIPID;

ALPHA CHAIN; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BETA CHAIN; CELL ACTIVATION; CELL HETEROGENEITY; CELL MATURATION; CELL STIMULATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CORRELATION ANALYSIS; HYBRIDOMA; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; LAMINA PROPRIA; LIVER CELL; MOUSE; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; TRANSGENIC MOUSE;

ANIMALS; CELL LINE, TUMOR; CERAMIDES; EPITOPES; GLYCOLIPIDS; HUMANS; KILLER CELLS, NATURAL; MANNOSE; MICE; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL;

MUS MUSCULUS;

EID: 34249061086     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2007.05826.x     Document Type: Article

References (40)

1. Bendelac A, Mivera NR, Park S-H Roark JH (1997)Mouse CD1-specific NK1 T cells; development, specificity, and function. Annu Rev Immunol 15, 535 562.
2. Lantz O Bendelac A (1994) An invariant T cell receptor α chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med 180, 1097 1106.
3. Makino Y, Kanno R, Ito T, Higashino K Taniguchi M (1995) Predominant expression of invariant Vα14+ TCR α chain in NK1.1+ T cell populations. Int Immunol 7, 1157 1161.
4. Kawano T, Cui J, Koezuka Y, Toura I, Kaneko Y, Motoki K, Ueno H, Nakagawa R, Sato H, Kondo E et al. (1997) CD1d-restricted and TCR-mediated activation of Vα14 NKT cells by glycosylceramides. Science 278, 1626 1629.
5. Natori T, Koezuka Y Higa T (1993) Agelasphins, novel α- galactosylceramides from the marine sponge Agelas Mauritianus. Tetrahedron Lett 34, 5591 5592.
6. Kinjo Y, Wu D, Kim G, Xing G-W, Poles MA, Ho DD, Tsuji M, Kawahara K, Wong C-H Kronenberg M (2005) Recognition of bacterial glycosphingolipids by natural killer T cell. Nature (Lond) 434, 520 525.
7. Mattner J, DeBord KL, Ismail N, Goff RD, Cantu C III., Zhou D, Saint-Mezard P, Wang V, Gao Y, Yin N et al. (2005) Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature (Lond) 434, 525 529.
8. Zhou D, Mattner J, Cantu C III., Schrantz N, Yin N, Gao Y, Sagiv Y, Hudspeth K, Wu Y-P, Yamashita T et al. (2004) Lysosomal glycosphingolipid recognition by NKT cells. Science 306, 1786 1789.
9. Bendelac A, Killeen N, Littman DR Schwarz RH (1994) A subset of CD4+ thymocytes selected by MHC class I molecules. Science 263, 1774 1778.
10. Bendelac A, Lantz O, Quimby ME, Yewdell JW, Bennink JR Brutkiewicz RR (1995) CD1 recognition by mouse NK1+ T lymphocytes. Science 268, 863 865.
11. Tilloy F, Treiner E, Park S-H, Garcia G, Lemonnier F, de la Salle H, Bendelac A, Bonneville M Lantz O (1999) An invariant T cell receptor α chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted α/β T cell subpopulation in mammals. J Exp Med 189, 1907 1921.
12. Shimamura M Huang Y-Y (2002) Presence of a novel subset of NKT cells bearing an invariant Vα19.1-Jα26 TCR α chain. FEBS Lett 516, 97 100.
13. Treiner E, Duban L, Bahram S, Radosavijevic M, Wanner V, Tilloy F, Affaticati P, Gilfillan S Lantz O (2003) Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature (Lond) 422, 164 169.
14. Okamoto N, Kanie O, Huang Y-Y, Fujii R, Watanabe H Shimamura M (2005) Synthetic α-mannosyl ceramide as a potent stimulant for a novel NKT cell repertoire bearing the invariant Vα19-Jα26 TCR α chain. Chem Biol 12, 677 683.
15. Kawachi I, Maldonado J, Strader C Gillfillan S (2006) MR1-restricted Vα19i mucosal-associated invariant T cells are innate T cells in the gut lamina propria that provide a rapid and diverse cytokine response. J Immunol 176, 1618 1627.
16. Croxford JL, Miyake S, Huang Y-Y, Shimamura M Yamamura T (2006) Invariant Vα19i T cells regulate autoimmune inflammation. Nat Immunol 7, 987 994.
17. Huang S, Gilfillan S, Cella M, Miley MJ, Lantz O, Lybarger L, Fremont DH Hansen TH (2005) Evidence for MR1 antigen presentation to mucosal-associated invariant T cells. J Biol Chem 280, 21183 21193.
18. Shimamura M, Okamoto N, Huang Y-Y, Yasuoka J, Morita K, Nishiyama A, Amano Y Mishina T (2006) Induction of promotive rather than suppressive immune responses from a novel NKT cell repertoire Vα19 NKT cell with α-mannosyl ceramide analogues consisting of the immunosuppressant ISP-I as the sphingosine unit. Eur J Med Chem 41, 569 576.
19. Ichikawa S, Sakiyama NH, Suzuki G, Hidari KI-PJ Hirabayashi Y (1994) Expression cloning of a cDNA for human ceramide glucosyltransferase that catalyzes the first glycosylation step of glycosphingolipid synthesis. Proc Natl Acad Sci USA 93, 4638 4643.
20. Watanabe R, Ohishi K, Maeda K, Nakamura N Kinoshita T (1999) Mammalian PIG-L and its yeast homologue Gpi12p are N- acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis. Biochem J 339, 185 192.
21. Watanabe Y, Yamamoto T Okazaki T (1997) Synthesis of 2,6-di-O-α-D- mannopyranosylphosphatidyl-D-myo-inositol. Utilization of glycosylation and phosphorylation based on phosphite chemistry. Tetrahedron 53, 903 918.
22. Murakata C Ogawa T (1992) Stereoselective synthesis of glycobiosyl phosphatidylinositol, a part structure of the glycosyl-phosphatidylinositol (GPI) anchor of Trypanosoma brucei. Carbohydr Res 234, 75 91.
23. Dickson RC Lester RL (1999) Yeast sphingolipids. Biochim Biophys Acta 14 (26 347 357.
24. Sumida M, Hashimoto M, Yasuoka J, Okabe E, Kusumoto S, Takada H, Hayashi T, Tamura T Kotani S (1996) Immuno-stimulating macromolecular glycolipids from bacterial cell surfaces. Polymer Preprints 37, 129 130.
25. Carter HE, Johnson P Weber EJ (1965) Glycolipids. Annu Rev Biochem 34, 109 142.
26. Mori T, Ito Y Ogawa T (1990) Total synthesis of mollu-series glycosyl ceramides. Carbohydr Res 195, 199 224.
27. Pulvertaft JV (1964) Cytology of Burkitt's tumor (African lymphoma). Lancet 1, 238 240.
28. Taniguchi M, Harada M, Kojo S, Nakayama T Wakao H (2003) The regulatory role of Vα14 NKT cells in innate and acquired immune response. Annu Rev Immunol 21, 483 513.
29. Miyamoto K, Miyake S Yamamura T (2001) A synthetic glycolipid prevents autoimmune encephalomyelitis by inducing TH2 bias of natural killer T cells. Nature (Lond) 413, 531 534.
30. Gumperz JE, Roy C, Makowska A, Lum D, Sugita M, Podrebarac T, Koezuka Y, Porcelli SA, Cardell S, Brenner MB et al. (2000) Murine CD1d-restricted T cell recognition of cellular lipids. Immunity 12, 211 221.
31. Kinjo Y, Tupin E, Wu D, Fujio M, Garcia-Navarro R, Benhnia MR-E-I, Zajonc DM, Ben-Menachem G, Aihge GD, Painer GF et al. (2006) Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol 7, 978 986.
32. Kinjo Y, Wu D, Kim G, Xing G-W, Poles MA, Ho DD, Tsuji M, Kawahara K, Wong C-H Kronenberg M (2005) Recognition of bacterial glycosphingolipids by natural killer T cells. Nature (Lond) 434, 520 525.
33. Fischer K, Scotet E, Niemeyer M, Koebernick H, Zerrahn J, Maillet S, Hurwitz R, Kursar M, Bonneville M, Kaufmann SHE et al. (2004) Mycobacterial phosphatidylinositol mannoside is a natural antigen for CD1d-restricted T cells. Proc Natl Acad Sci USA 101, 10685 10690.
34. Ilés Z, Shimamura M, Newcombe J, Oka N Yamamura T (2004) Accumulation of Vα7.2-Jα33 invariant T cells in human autoimmune inflammatory lesions. Int Immunol 16, 223 230.
35. Mombaerts P, Clarke AR, Rudnicki MA, Iacomini J, Itohara S, Lafáille JJ, Wang L, Ichikawa Y, Jaenisch RL, Hooper M et al. (1992) Mutations in T cell receptor genes α and β block thymocyte development at different stages. Nature (Lond) 360, 225 231.
36. Shimamura M, Ohteki T, Launois P, Garcia A-M MacDonald HR (1997) Thymus-independent generation of NK1+ T cells in vitro from fetal liver precursors. J Immunol 158, 3682 3689.
37. Yamaguchi H, Hirai M, Kurokawa Y Hashimoto K (1997) A highly conserved major histocompatibility complex class I-related gene in mammals. Biochem Biophys Res Commun 238, 697 702.
38. Niwa H, Yamamura K Miyazaki J (1991) Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108, 193 199.
39. Hashimoto K, Hirai M Kurosawa Y (1995) A gene outside the human MHC related to classical HLA class I genes. Science 269, 693 695.
40. Shimamura M, Ohteki T, Beutner U MacDonald HR (1997) Lack of directed Vα14-Jα281 rearrangements in NK1+ T cells. Eur J Immunol 27, 1576 1579.