Action of GLP-1 (7-36) amide and exendin-4 on Suncus murinus (house musk shrew) isolated ileum

European Journal of Pharmacology

Volumn 566, Issue 1-3, 2007, Pages 185-191

  Chan, Sze Wa ^a   He, Jufang ^b   Lin, Ge ^a   A Rudd, John ^a   Yamamoto, Kouichi ^c  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Diabetes; Emesis; Exendin (9 39) amide; Exendin 4; GLP 1; Ileum; Nausea; Postganglionic enteric neurone; Suncus murinus

Indexed keywords

AMIDE; ATROPINE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCAGON LIKE PEPTIDE 1 [7-36] AMIDE; HEXAMETHONIUM; LIGAND; MUSCARINIC RECEPTOR; TETRODOTOXIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; ILEUM; ILEUM CONTRACTION; MALE; NONHUMAN; POSTGANGLIONIC NERVE; PRIORITY JOURNAL; REGULATORY MECHANISM; SHREW;

EID: 34249052196     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.03.050     Document Type: Article

References (42)

1. Ayachi S.E., Borie F., Magous R., Sasaki K., Le Nguyen D., Bali J.P., Millat B., and Jarrousse C. Contraction induced by glicentin on smooth muscle cells from the human colon is abolished by exendin (9-39). Neurogastroenterol. Motil. 17 (2005) 302-309
2. Beinborn M., Worrall C.I., McBride E.W., and Kopin A.S. A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness. Regul. Pept. 130 (2005) 1-6
3. Bullock B.P., Heller R.S., and Habener J.F. Tissue distribution of messenger ribonucleic acid encoding the rat glucagon-like peptide-1 receptor. Endocrinology 137 (1996) 2968-2978
4. Buse J.B., Henry R.R., Han J., Kim D.D., Fineman M.S., and Baron A.D. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care 27 (2004) 2628-2635
5. 2 receptors in the modulation of the peristaltic reflex of the guinea pig isolated ileum. Eur. J. Pharmacol. 539 (2006) 108-115
6. Drucker D.J. Biological actions and therapeutic potential of the glucagon-like peptides. Gastroenterology 122 (2002) 531-544
7. Eissele R., Goke R., Willemer S., Harthus H.P., Vermeer H., Arnold R., and Goke B. Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur. J. Clin. Investig. 22 (1992) 283-291
8. Eng J., Kleinman W.A., Singh L., Singh G., and Raufman J.P. Isolation and characterization of exendin-4, an exendin-3 analog, from Heloderma-suspectum venom - further evidence for an exendin receptor on dispersed acini from guinea-pig pancreas. J. Biol. Chem. 267 (1992) 7402-7405
9. Gaddum J.H., Hameed K.A., Hathway D.E., and Stephens F.F. Quantitative studies of antagonists for 5-hydroxytryptamine. Q. J. Exp. Physiol. Cogn. Med. Sci. 40 (1955) 49-74
10. Galligan J.J. Nerve terminal nicotinic cholinergic receptors on excitatory motoneurons in the myenteric plexus of guinea pig intestine. J. Pharmacol. Exp. Ther. 291 (1999) 92-98
11. Goke R., Fehmann H.C., Richter G., Trautmann M., and Goke B. Interaction of glucagon-like peptide-1(7-36)amide and somatostatin-14 in RINm5F cells and in the perfused rat pancreas. Pancreas 4 (1989) 668-673
12. Goke R., Fehmann H.C., Linn T., Schmidt H., Krause M., Eng J., and Goke B. Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells. J. Biol. Chem. 268 (1993) 19650-19655
13. Gutzwiller J.P., Goke B., Drewe J., Hildebrand P., Ketterer S., Handschin D., Winterhalder R., Conen D., and Beglinger C. Glucagon-like peptide-1: a potent regulator of food intake in humans. Gut 44 (1999) 81-86
14. Hellstrom P.M., and Naslund E. Interactions between gastric emptying and satiety, with special reference to glucagon-like peptide-1. Physiol. Behav. 74 (2001) 735-741
15. Holst J.J., Orskov C., Nielsen O.V., and Schwartz T.W. Truncated glucagon-like peptide 1, an insulin-releasing hormone from the distal gut. FEBS Lett. 211 (1987) 169-174
16. Irwin D.M. Molecular evolution of proglucagon. Regul. Pept. 98 (2001) 1-12
17. 2 receptor subtypes in the Suncus murinus intestine. Eur. J. Pharmacol. 381 (1999) 161-169
18. Javid F.A., and Naylor R.J. Characterization of the 5-hydroxytryptamine receptors mediating contraction in the intestine of Suncus murinus. Br. J. Pharmacol. 127 (1999) 1867-1875
19. Kanamori Y., Nakazawa S., Kitoh J., and Hoshino M. The distribution of endocrine cells in the mucosa of the gastrointestinal tract of the house musk shrew, Suncus murinus (Insectivora). Cell Tissue Res. 258 (1989) 365-371
20. Kieffer T.J., Heller R.S., Unson C.G., Weir G.C., and Habener J.F. Distribution of glucagon receptors on hormone-specific endocrine cells of rat pancreatic islets. Endocrinology 137 (1996) 5119-5125
21. Kiso Y., Oku K., and Yamauchi S. Prenatal and postnatal development of the small intestine in the insectivore Suncus murinus. Am. J. Anat. 183 (1988) 57-67
22. Kreymann B., Williams G., Ghatei M.A., and Bloom S.R. Glucagon-like peptide-1 7-36: a physiological incretin in man. Lancet 2 (1987) 1300-1304
23. Kurohmaru M., Nishida T., and Mochizuki K. Morphological study on the intestine of the must shrew, Suncus murinus. Nippon Juigaku Zasshi 42 (1980) 61-71
24. Lecci A., Santicioli P., and Maggi C.A. Pharmacology of transmission to gastrointestinal muscle. Curr. Opin. Pharmacol. 2 (2002) 630-641
25. Lew M.J., and Angus J.A. Reversible inhibition of neuronal uptake by benextramine, an irreversible presynaptic alpha-adrenoceptor antagonist. Eur. J. Pharmacol. 98 (1984) 27-34
26. Matsuo K., Kaibara M., Uezono Y., Hayashi H., Taniyama K., and Nakane Y. Involvement of cholinergic neurons in orexin-induced contraction of guinea pig ileum. Eur. J. Pharmacol. 452 (2002) 105-109
27. Mayo K.E., Miller L.J., Bataille D., Dalle S., Goke B., Thorens B., and Drucker D.J. International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol. Rev. 55 (2003) 167-194
28. Muraki T., Fujii E., Uchida Y., Furukawa K., Irie K., and Nomoto T. Characterization of drug responses of the intestine of the house musk shrew (Suncus-murinus). Comp. Biochem. Physiol. C 91 (1988) 613-617
29. Naslund E., Gutniak M., Skogar S., Rossner S., and Hellstrom P.M. Glucagon-like peptide 1 increases the period of postprandial satiety and slows gastric emptying in obese men. Am. J. Clin. Nutr. 68 (1998) 525-530
30. Novacek M.J. Mammalian phylogeny: shaking the tree. Nature 356 (1992) 121-125
31. Ohno T., Yoshida F., Ichikawa Y., Matsuo S., Hotta N., Terada M., Tanaka S., Yamashita K., Namikawa T., and Kitoh J. A new spontaneous animal model of NIDDM without obesity in the musk shrew. Life Sci. 62 (1998) 995-1006
32. Orskov C., Bersani M., Johnsen A.H., Hojrup P., and Holst J.J. Complete sequences of glucagon-like peptide-1 from human and pig small intestine. J. Biol. Chem. 264 (1989) 12826-12829
33. Perry T., and Greig N.H. The glucagon-like peptides: a double-edged therapeutic sword? Trends Pharmacol. Science 24 (2003) 377-383
34. Raufman J.P., Singh L., Singh G., and Eng J. Truncated glucagon-like peptide-1 interacts with exendin receptors on dispersed acini from guinea pig pancreas. Identification of a mammalian analogue of the reptilian peptide exendin-4. J. Biol. Chem. 267 (1992) 21432-21437
35. Ritzel R., Orskov C., Holst J.J., and Nauck M.A. Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships. Diabetologia 38 (1995) 720-725
36. Schemann M. Control of gastrointestinal motility by the "gut brain" - the enteric nervous system. J. Pediatr. Gastroenterol. Nutr. 41 Suppl. 1 (2005) S4-S6
37. 2. Eur. J. Pharmacol. 269 (1994) 183-191
38. Schneider D.A., and Galligan J.J. Presynaptic nicotinic acetylcholine receptors in the myenteric plexus of guinea pig intestine. Am. J. Physiol.: Gasterointest. Liver Physiol. 279 (2000) G528-G535
39. Spencer N.J., Hennig G.W., and Smith T.K. Electrical rhythmicity and spread of action potentials in longitudinal muscle of guinea pig distal colon. Am. J. Physiol.: Gasterointest. Liver Physiol. 282 (2002) G904-G917
40. Tolessa T., Gutniak M., Holst J.J., Efendic S., and Hellstrom P.M. Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin. J. Clin. Invest. 102 (1998) 764-774
41. Ueno S., Matsuki N., and Saito H. Suncus murinus: a new experimental model in emesis research. Life Sci. 41 (1987) 513-518
42. Wettergren A., Schjoldager B., Mortensen P.E., Myhre J., Christiansen J., and Holst J.J. Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man. Dig. Dis. Sci. 38 (1993) 665-673