-
1
-
-
34249004650
-
-
American Society of Cancer. Available at: www.cancer.org. Accessed April 12, 2007.
-
-
-
-
2
-
-
0034690750
-
UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years
-
Peto R., Boreham J., Clarke M., et al. UK and USA breast cancer deaths down 25% in year 2000 at ages 20-69 years. Lancet 355 (2000) 1822
-
(2000)
Lancet
, vol.355
, pp. 1822
-
-
Peto, R.1
Boreham, J.2
Clarke, M.3
-
3
-
-
3042623269
-
The impact of new chemotherapeutic and hormonal agents on the survival of women with metastatic breast cancer (MBC) in a population based cohort
-
[abstract 22]
-
Chia S., Speers C., Kang A., et al. The impact of new chemotherapeutic and hormonal agents on the survival of women with metastatic breast cancer (MBC) in a population based cohort. [abstract 22]. Proc Am Soc Clin Oncol 22 (2003) 6
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 6
-
-
Chia, S.1
Speers, C.2
Kang, A.3
-
4
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon D.J., Clark G.M., Wong S.G., et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235 (1987) 177-182
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
5
-
-
0024337144
-
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer
-
Slamon D.J., Godolphin W., Jones L.A., et al. Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science 244 (1989) 707-712
-
(1989)
Science
, vol.244
, pp. 707-712
-
-
Slamon, D.J.1
Godolphin, W.2
Jones, L.A.3
-
6
-
-
0033779252
-
Biological rationale for HER2/neu (c-erbB2) as a target for monoclonal antibody therapy
-
Pegram M., and Slamon D. Biological rationale for HER2/neu (c-erbB2) as a target for monoclonal antibody therapy. Semin Oncol 27 5 Suppl 9 (2000) 13-19
-
(2000)
Semin Oncol
, vol.27
, Issue.5 SUPPL. 9
, pp. 13-19
-
-
Pegram, M.1
Slamon, D.2
-
7
-
-
0029039990
-
The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers-a review
-
Ravdin P.M., and Chamness G.C. The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers-a review. Gene 159 (1995) 19-27
-
(1995)
Gene
, vol.159
, pp. 19-27
-
-
Ravdin, P.M.1
Chamness, G.C.2
-
8
-
-
0036467826
-
Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer
-
Vogel C.L., Cobleigh M.A., Tripathy D., et al. Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer. J Clin Oncol 20 (2002) 719-726
-
(2002)
J Clin Oncol
, vol.20
, pp. 719-726
-
-
Vogel, C.L.1
Cobleigh, M.A.2
Tripathy, D.3
-
9
-
-
17144371333
-
Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule
-
Baselga J., Carbonell X., Castañeda-Soto N.J., et al. Phase II study of efficacy, safety, and pharmacokinetics of trastuzumab monotherapy administered on a 3-weekly schedule. J Clin Oncol 23 (2005) 2162-2171
-
(2005)
J Clin Oncol
, vol.23
, pp. 2162-2171
-
-
Baselga, J.1
Carbonell, X.2
Castañeda-Soto, N.J.3
-
10
-
-
0035869407
-
Concurrent administration of anti-HER2 monoclonal antibody and first-line chemotherapy for HER2-overexpressing metastatic breast cancer. A phase III, multinational, randomized controlled trial
-
Slamon D.J., Leyland-Jones B., Shak S., et al. Concurrent administration of anti-HER2 monoclonal antibody and first-line chemotherapy for HER2-overexpressing metastatic breast cancer. A phase III, multinational, randomized controlled trial. N Engl J Med 344 (2001) 783-792
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
11
-
-
0035873822
-
Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer
-
Burstein H.J., Kurten I., Campos S.M., et al. Clinical activity of trastuzumab and vinorelbine in women with HER2-overexpressing metastatic breast cancer. J Clin Oncol 19 10 (2001) 2722-2730
-
(2001)
J Clin Oncol
, vol.19
, Issue.10
, pp. 2722-2730
-
-
Burstein, H.J.1
Kurten, I.2
Campos, S.M.3
-
12
-
-
22344446208
-
Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 Study Group
-
Marty M., Cognetti F., Maraninchi D., et al. Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 Study Group. J Clin Oncol 23 (2005) 4265-4274
-
(2005)
J Clin Oncol
, vol.23
, pp. 4265-4274
-
-
Marty, M.1
Cognetti, F.2
Maraninchi, D.3
-
13
-
-
1242311596
-
What can we learn from Herceptin trials in metastatic breast cancer?
-
Bell R. What can we learn from Herceptin trials in metastatic breast cancer?. Oncology 63 Suppl 1 (2002) 39-46
-
(2002)
Oncology
, vol.63
, Issue.SUPPL. 1
, pp. 39-46
-
-
Bell, R.1
-
14
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart M.J., Procter M., Leyland-Jones B., et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 353 (2005) 1659-1672
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
15
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond E.H., Perez E.A., Bryant J., et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 353 (2005) 1673-1684
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
16
-
-
33745435244
-
Trastuzumab sensitivity of breast cancer with coamplification of HER2 and cMYC suggests pro-apoptopic function of dysregulated cMYC in vivo [abstract 46].
-
Kim C., Bryant J., Home Z., et al. Trastuzumab sensitivity of breast cancer with coamplification of HER2 and cMYC suggests pro-apoptopic function of dysregulated cMYC in vivo [abstract 46]. Breast Cancer Res Treat 94 Suppl 1 (2006) S6
-
(2006)
Breast Cancer Res Treat
, vol.94
, Issue.SUPPL. 1
-
-
Kim, C.1
Bryant, J.2
Home, Z.3
-
17
-
-
33947317453
-
BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients.
-
abstract 25
-
Slamon D., Eiermann W., Robert N., et al. BCIRG 006: 2nd interim analysis phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (AC→T) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (AC→TH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2 positive early breast cancer patients. Breast Cancer Res Treat 100 (2006) abstract 25
-
(2006)
Breast Cancer Res Treat
, vol.100
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
18
-
-
33344478381
-
Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer
-
Joensuu H., Kellokumpu-Lehtinen P.L., Bono P., et al. Adjuvant docetaxel or vinorelbine with or without trastuzumab for breast cancer. N Engl J Med 354 (2006) 809-820
-
(2006)
N Engl J Med
, vol.354
, pp. 809-820
-
-
Joensuu, H.1
Kellokumpu-Lehtinen, P.L.2
Bono, P.3
-
19
-
-
33845914783
-
2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial
-
Smith I., Procter M., Gelber R., et al. 2-year follow-up of trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer: a randomised controlled trial. Lancet 369 9555 (2007) 29-36
-
(2007)
Lancet
, vol.369
, Issue.9555
, pp. 29-36
-
-
Smith, I.1
Procter, M.2
Gelber, R.3
-
20
-
-
0038010542
-
Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma
-
Bendell J.C., Domchek S.M., Burstein H.J., et al. Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma. Cancer 97 (2003) 2972-2977
-
(2003)
Cancer
, vol.97
, pp. 2972-2977
-
-
Bendell, J.C.1
Domchek, S.M.2
Burstein, H.J.3
-
21
-
-
0036498781
-
Cardiac dysfunction in the trastuzumab clinical trials experience
-
Seidman A., Hudis C., Pierri M., et al. Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol 20 5 (2002) 1215-1221
-
(2002)
J Clin Oncol
, vol.20
, Issue.5
, pp. 1215-1221
-
-
Seidman, A.1
Hudis, C.2
Pierri, M.3
-
22
-
-
1342311012
-
Clinical cardiac tolerability of trastuzumab
-
Perez E.A., and Rodeheffer R. Clinical cardiac tolerability of trastuzumab. J Clin Oncol 22 2 (2004) 322-329
-
(2004)
J Clin Oncol
, vol.22
, Issue.2
, pp. 322-329
-
-
Perez, E.A.1
Rodeheffer, R.2
-
23
-
-
33745935167
-
Anti-ErbB2 treatment induces cardiotoxicity by interfering with cell survival pathways
-
Pugatsch T., Abedat S., Lotan C., et al. Anti-ErbB2 treatment induces cardiotoxicity by interfering with cell survival pathways. Breast Cancer Res 8 (2006) R35
-
(2006)
Breast Cancer Res
, vol.8
-
-
Pugatsch, T.1
Abedat, S.2
Lotan, C.3
-
24
-
-
33344458106
-
Herceptin and the heart-a molecular modifier of cardiac failure
-
Chien K.R. Herceptin and the heart-a molecular modifier of cardiac failure. N Engl J Med 354 (2006) 789-790
-
(2006)
N Engl J Med
, vol.354
, pp. 789-790
-
-
Chien, K.R.1
-
25
-
-
0037172982
-
Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy
-
Ozcelik C., Erdmann B., Pilz B., et al. Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy. Proc Natl Acad Sci U S A 99 13 (2002) 8880-8885
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.13
, pp. 8880-8885
-
-
Ozcelik, C.1
Erdmann, B.2
Pilz, B.3
-
26
-
-
19444378256
-
Type II chemotherapy-related cardiac dysfunction: time to recognize a new entity
-
Ewer M., and Lippman S. Type II chemotherapy-related cardiac dysfunction: time to recognize a new entity. J Clin Oncol 23 13 (2005) 2900-2902
-
(2005)
J Clin Oncol
, vol.23
, Issue.13
, pp. 2900-2902
-
-
Ewer, M.1
Lippman, S.2
-
27
-
-
29744442709
-
Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31
-
Tan-Chiu E., Yothers G., Romond E., et al. Assessment of cardiac dysfunction in a randomized trial comparing doxorubicin and cyclophosphamide followed by paclitaxel, with or without trastuzumab as adjuvant therapy in node-positive, human epidermal growth factor receptor 2-overexpressing breast cancer: NSABP B-31. J Clin Oncol 23 31 (2005) 7811-7819
-
(2005)
J Clin Oncol
, vol.23
, Issue.31
, pp. 7811-7819
-
-
Tan-Chiu, E.1
Yothers, G.2
Romond, E.3
-
28
-
-
28044453732
-
The other side of the coin
-
Gopalakrishnan S., and Linnane J. The other side of the coin. BMJ 331 (2005) 1202-1203
-
(2005)
BMJ
, vol.331
, pp. 1202-1203
-
-
Gopalakrishnan, S.1
Linnane, J.2
-
29
-
-
29744461119
-
Trastuzumab for early breast cancer: evolution or revolution?
-
Littlejohns P. Trastuzumab for early breast cancer: evolution or revolution?. Lancet Oncol 7 1 (2006) 22-23
-
(2006)
Lancet Oncol
, vol.7
, Issue.1
, pp. 22-23
-
-
Littlejohns, P.1
-
30
-
-
33644670516
-
An economic evaluation of Herceptin® in adjuvant setting: the Breast Cancer International Research Group 006 trial
-
Neyt M., Albrecht J., and Cocquyt V. An economic evaluation of Herceptin® in adjuvant setting: the Breast Cancer International Research Group 006 trial. Ann Oncol 17 3 (2006) 381-390
-
(2006)
Ann Oncol
, vol.17
, Issue.3
, pp. 381-390
-
-
Neyt, M.1
Albrecht, J.2
Cocquyt, V.3
-
31
-
-
34249000751
-
Cost-effectiveness analysis of trastuzumab in the adjuvant setting for treatment of HER2+ breast cancer
-
Garrison L.P., Perez E.A., Dueck A., et al. Cost-effectiveness analysis of trastuzumab in the adjuvant setting for treatment of HER2+ breast cancer. J Clin Oncol 24 18S (2006) 306s
-
(2006)
J Clin Oncol
, vol.24
, Issue.18 S
-
-
Garrison, L.P.1
Perez, E.A.2
Dueck, A.3
-
32
-
-
34249111950
-
Access to trastuzumab in the adjuvant treatment of patients with HER-2 positive breast cancer: the challenges of applying the benefits
-
Ismael G. Access to trastuzumab in the adjuvant treatment of patients with HER-2 positive breast cancer: the challenges of applying the benefits. Breast International Group Newsletter 8 (2006) 7-10
-
(2006)
Breast International Group Newsletter
, vol.8
, pp. 7-10
-
-
Ismael, G.1
-
33
-
-
0037341394
-
Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study
-
Joensuu H., Isola J., Lundin M., et al. Amplification of erbB2 and erbB2 expression are superior to estrogen receptor status as risk factors for distant recurrence in pT1N0M0 breast cancer: a nationwide population-based study. Clin Cancer Res 9 (2003) 923-930
-
(2003)
Clin Cancer Res
, vol.9
, pp. 923-930
-
-
Joensuu, H.1
Isola, J.2
Lundin, M.3
-
34
-
-
33646439130
-
Prognosis and management of patients with node-negative invasive breast carcinoma that is 1 cm or smaller in size (stage 1; T1a,bN0M0)
-
Hanrahan E.O., Valero V., Gonzalez-Angulo A.M., et al. Prognosis and management of patients with node-negative invasive breast carcinoma that is 1 cm or smaller in size (stage 1; T1a,bN0M0). J Clin Oncol 24 13 (2006) 2113-2122
-
(2006)
J Clin Oncol
, vol.24
, Issue.13
, pp. 2113-2122
-
-
Hanrahan, E.O.1
Valero, V.2
Gonzalez-Angulo, A.M.3
|