Effects of imipramine on extracellular serotonin and noradrenaline concentrations in ACTH-treated rats

European Journal of Pharmacology

Volumn 566, Issue 1-3, 2007, Pages 113-116

  Kitamura, Yoshihisa ^a,b   Akiyama, Kozue ^b   Hashimoto, Shinji ^c   Kitagawa, Kouhei ^b   Kawasaki, Hiromu ^a   Shibata, Kazuhiko ^b   Shinomiya, Kazuaki ^a,b   Suemaru, Katsuya ^d   Araki, Hiroaki ^d   Sendo, Toshiaki ^b   Gomita, Yutaka ^b  

^a OKAYAMA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c Asahi Kasei Pharma Corporation   (Japan)

^d EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

5 HT1A receptor; 8 hydroxy 2 di n propylamino tetralin; Adrenocorticotropic hormone; Imipramine; Microdialysis

Indexed keywords

2 DIPROPYLAMINO 8 HYDROXYTETRALIN; CORTICOTROPIN; IMIPRAMINE; NORADRENALIN; SEROTONIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXTRACELLULAR MATRIX; MALE; MICRODIALYSIS; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; RAT; RECEPTOR BINDING;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ADRENERGIC UPTAKE INHIBITORS; ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CORTICOSTERONE; IMIPRAMINE; MALE; NOREPINEPHRINE; PREFRONTAL CORTEX; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; SEROTONIN; SEROTONIN AGONISTS;

EID: 34249037043     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.03.012     Document Type: Article

References (12)

1. Arora R.C., and Meltzer H.Y. Effect of adrenalectomy and corticosterone on [3H]imipramine binding in rat blood platelets and brain. Eur. J. Pharmacol. 123 (1986) 415-419
2. Artigas F., Bel N., Casanovas J.M., and Romero L. Adaptative changes of the serotonergic system after antidepressant treatments. Adv. Exp. Med. Biol. 398 (1996) 51-59
3. Bel N., and Artigas F. Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei. Synapse 15 (1993) 243-245
4. Ferraro L., Fuxe K., Agnati L., Tanganelli S., Tomasini M.C., and Antonelli T. Modafinil enhances the increase of extracellular serotonin levels induced by the antidepressant drugs fluoxetine and imipramine: a dual probe microdialysis study in awake rat. Synapse 55 (2005) 230-241
5. Hamon M., Fattaccini C.M., Adrien J., Gallissot M.C., Martin P., and Gozlan H. Alterations of central serotonin and dopamine turnover in rats treated with ipsapirone and other 5-hydroxytryptamine1A agonists with potential anxiolytic properties. J. Pharmacol. Exp. Ther. 246 (1988) 745-752
6. Jolas T., Haj-Dahmane S., Kidd E.J., Langlos X., Lanfumey L., Fattaccini C.M., Vantalon V., Laporte A.M., Adrien J., Gozla H., and Hamon M. Central pre-and postsynaptic 5-HT1A receptors in rats treated chronically with a novel antidepressant, cericlamine. J. Pharmacol. Exp. Ther. 268 (1993) 1432-1443
7. Kitamura Y., Araki H., and Gomita Y. Influence of ACTH on the effects of imipramine, desipramine and lithium on the duration of immobility of rats in the forced swim test. Pharmacol. Biochem. Behav. 71 (2002) 63-69
8. Laaris N., Haj-dahmane S., Hamon M., and Lanfumey L. Glucocorticoid receptor-mediated inhibition by corticosterone of 5-HT1A autoreceptor functioning in the rat dorsal raphe nucleus. Neuropharmacology 34 (1995) 1201-1210
9. Mochizuki D., Tsujita R., Yamada S., Kawasaki K., Otsuka Y., Hashimoto S., Hattori T., Kitamura Y., and Miki N. Neurochemical and behavioural characterization of milnacipran, a serotonin and noradrenaline reuptake inhibitor in rats. Psychopharmacol 162 (2002) 323-332
10. Mochizuki D., Hokonohara T., Kawasaki K., and Miki N. Repeated administration of milnacipran induces rapid desensitization of somatodendritic 5-HT1A autoreceptors but not postsynaptic 5-HT1A receptors. J. Psychopharmacol. 16 (2002) 253-260
11. Sharp T., Bramwell S.T., and Grahame-Smith D.G. 5-HT1 agonists reduce 5-hydroxytryptamine release in rat hippocampus in vivo as determined by brain microdialysis. Br. J. Pharmacol. 96 (1989) 283-290
12. Sprouse J.S., and Aghajanian G.K. Electrophysiological responses of serotonergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonist. Synapse 1 (1987) 3-9