Comparative in vitro metabolism of 14C-ciclesonide in hepatocytes from the mouse, rat, rabbit, dog, and human

American Journal of Therapeutics

Volumn 14, Issue 3, 2007, Pages 280-290

  Gu, Zheming ^a   Zhao, Xian Guo ^a   Nave, Ruediger ^b   Liu, Dave D W ^a   Feng, Hao ^a   Wu, Jinn ^a   Howell, Stanley R ^c,d   Guo, Zuyu ^c  

^a XENOBIOTIC LABORATORIES INC   (United States)

^b Altana Pharma Deutschland   (Germany)

^c SANOFI   (France)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

Ciclesonide; Hepatocytes; In vitro metabolism

Indexed keywords

CARBON 14; CICLESONIDE; CYCLOHEXANE; DESISOBUTYRYLCICLESONIDE; DRUG METABOLITE; GLYCINE; HIPPURIC ACID; METHYLCYCLOHEXANE; STEROID; UNCLASSIFIED DRUG;

ANIMAL CELL; AROMATIZATION; ARTICLE; COMPARATIVE STUDY; CONJUGATION; CONTROLLED STUDY; DEHYDRATION; DOG; DRUG METABOLISM; GLUCURONIDATION; HUMAN; HUMAN CELL; HYDROXYLATION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER CELL; LIVER METABOLISM; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RABBIT; RADIOACTIVITY; RAT; REDUCTION;

ANIMALS; ANTI-ALLERGIC AGENTS; DOGS; HEPATOCYTES; HUMANS; MALE; MICE; MICE, INBRED ICR; PREGNENEDIONES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

EID: 34249027887     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mjt.0000209691.75442.de     Document Type: Article

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