Poly(ADP-ribose) polymerase inhibition by cilostazol is implicated in the neuroprotective effect against focal cerebral ischemic infarct in rat

Brain Research

Volumn 1152, Issue 1, 2007, Pages 182-190

  Lee, Jeong Hyun ^a   Park, So Youn ^a   Shin, Hwa Kyung ^b   Kim, Chi Dae ^a,c   Lee, Won Suk ^a,c   Hong, Ki Whan ^c  

^a Pusan National University School of Medicine   (South Korea)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c Pusan National University   (South Korea)

Author keywords

Anti inflammation; Cilostazol; Middle cerebral artery occlusion; Neuroprotection; Poly(ADP ribose) polymerase

Indexed keywords

APOPTOSIS INDUCING FACTOR; CELL MARKER; CILOSTAZOL; HYDROGEN PEROXIDE; MYELOPEROXIDASE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OX 42; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; EVOKED RESPONSE; IC 50; IN VIVO STUDY; MALE; MICROGLIA; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NEUTROPHIL CHEMOTAXIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; REPERFUSION;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD11; APOPTOSIS INDUCING FACTOR; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; ISCHEMIC ATTACK, TRANSIENT; MALE; NAD; NEUROPROTECTIVE AGENTS; PC12 CELLS; PEROXIDASE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; TETRAZOLES; TUMOR NECROSIS FACTOR-ALPHA;

RATTUS;

EID: 34249027558     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.03.035     Document Type: Article

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