Interrelationship of childhood trauma, neuroticism, and depressive phenotype

Depression and Anxiety

Volumn 24, Issue 3, 2007, Pages 163-168

  Moskvina, Valentina ^a   Farmer, Anne ^b   Swainson, Victoria ^a   O'Leary, Joanna ^b   Gunasinghe, Cerise ^b   Owen, Mike ^a   Craddock, Nick ^a   McGuffin, Peter ^b   Korszun, Ania ^c  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Childhood trauma; Depression

Indexed keywords

ADULT; AGED; ARTICLE; CHILDHOOD DISEASE; CHILDHOOD TRAUMA; CORRELATION ANALYSIS; DEPRESSION; EXTRAVERSION; FEMALE; GENETIC PREDISPOSITION; HUMAN; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; NEUROSIS; ONSET AGE; PATHOGENESIS; PERSONALITY; PRIORITY JOURNAL; RECURRENT DISEASE; STRUCTURED INTERVIEW;

ADOLESCENT; ADULT; AGE OF ONSET; CASE-CONTROL STUDIES; CHILD; CHILD ABUSE; CHILD, PRESCHOOL; DEPRESSIVE DISORDER; HUMANS; INTERNATIONAL CLASSIFICATION OF DISEASES; MIDDLE AGED; NEUROTIC DISORDERS; OBSERVER VARIATION; PERSONALITY DISORDERS; PHENOTYPE; PREVALENCE; QUESTIONNAIRES; SEVERITY OF ILLNESS INDEX; SIBLINGS; STRESS DISORDERS, POST-TRAUMATIC;

EID: 34249019808     PISSN: 10914269     EISSN: 15206394     Source Type: Journal    
DOI: 10.1002/da.20216     Document Type: Article

References (31)

1. American Psychiatric Association. 1994. Diagnostic and statistical manual of mental disorders. 4th ed. Washington, DC: Author.
2. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. 1961. An inventory for measuring depression. Arch Gen Psychiatry 4: 561-571.
3. Bernet CZ, Stein MB. 1999. Relationship of childhood maltreatment to the onset and course of major depression in adulthood. Depress Anxiety 9:169-174.
4. Bifolco A, Brown GW, Moran P, Ball C, Campbell C. 1998. Predicting depression in women: the role of past and present vulnerability. Psychol Med 28:39-50.
5. Bland RC, Newman SC, Orn H. 1986. Recurrent and nonrecurrent depression. A family study. Arch Gen Psychiatry 43:1085-1089.
6. Boyce P, Parker G. 1985. Neuroticism as a predictor of outcome in depression. J Nerv Ment Dis 173:685-688.
7. Eysenck HJ, Eysenck SBG. 1975. Manual of the Eysenck Personality Questionnaire. London: Hodder and Stoughton.
8. Fanous A, Gardner CO, Prescott CA, Cancro R, Kendler KS. 2002. Neuroticism, major depression and gender: a population-based twin study. Psychol Med 32:719-728.
9. Fanous AH, Kendler KS. 2004. The genetic relationship of personality to major depression and schizophrenia. Neurotox Res 6:43-50.
10. Farmer A, Redman K, Harris T, Mahmood A, Sadler S, Pickering A, McGuffin P. 2002. Neuroticism, extraversion, life events and depression: The Cardiff Depression Study. Br J Psychiatry 181: 118-122.
11. Farmer A, Redman K, Harris T, Webb R, Mahmood A, Sadler S, McGuffin P. 2001. The Cardiff sib-pair study: Suicidal ideation in depressed and healthy subjects and their siblings. Crisis 22:71-73.
12. Gladstone GL, Parker GB, Mitchell PB, Malhi GS, Wilhelm K, Austin MP. 2004. Implications of childhood trauma for depressed women: An analysis of pathways from childhood sexual abuse to deliberate self-harm and revictimization. Am J Psychiatry 161: 1417-1425.
13. Gladstone GL, Parker G, Wilhelm K, Mitchell P, Austin MP. 1999. Characteristics of depressed patients who report childhood sexual abuse. Am J Psychiatry 156:431-437.
14. Gorey KM, Leslie DR. 2005. The prevalence of child sexual abuse: Integrative review adjustment for potential response and measurement biases. Child Abuse Negl 21:391-398.
15. Heim C, Plotsky PM, Nemeroff CB. 2004. Importance of studying the contributions of early adverse experience to neurobiological findings in depression. Neuropsychopharmacology 29:641-648.
16. Jaffee SR, Moffitt TE, Caspi A, Fombonne E, Poulton R, Martin J. 2002. Differences in early childhood risk factors for juvenile-onset and adult-onset depression. Arch Gen Psychiatry 59:215-222.
17. Kendler KS. 1998. Major depression and the environment: A psychiatric genetic perspective. Pharmacopsychiatry 31:5-9.
18. Kendler KS, Gardner CO, Prescott CA. 2002. Toward a comprehensive developmental model for major depression in women. Am J Psychiatry 159:1133-1145.
19. Korszun A, Moskvina V, Brewster S, Craddock N, Ferrero F, Gill M, Jones IR, Jones LA, Maier W, Mors O, Owen MJ, Preisig M, Reich T, Rietschel M, Farmer A, McGuffin P. 2004. Familiality of symptom dimensions in depression. Arch Gen Psychiatry 61: 468-474.
20. Lyons MJ, Eisen SA, Goldberg J, True W, Lin N, Meyer JM, Toomey R, Faraone SV, Merla-Ramos M, Tsuang MT 1998. A registry-based twin study of depression in men. Arch Gen Psychiatry 55:468-472.
21. MacMillan HL, Fleming JE, Trocme N, Boyle MH, Wong M, Racine YA, Beardslee WR, Offord DR. 1997. Prevalence of child physical and sexual abuse in the community: Results from the Ontario Health Supplement. JAMA 278:131-135.
22. Matza S, Revicki DA, Davidson JR, Stewart JW. 2003. Depression with atypical features in the National Comorbidity Survey: Classification, description, and consequences. Arch Gen Psychiatry 60:817-826.
23. McGuffin P, Katz R, Watkins S, Rutherford J. 1996. A hospital-based twin register of the heritability of DSM-IV unipolar depression. Arch Gen Psychiatry 53:129-136.
24. Ormel J, Oldehinkel AJ, Brilman EI. 2001. The interplay and etiological continuity of neuroticism, difficulties, and life events in the etiology of major and subsyndromal, first and recurrent depressive episodes in later life. Am J Psychiatry 158:885-891.
25. Roberts SB, Kendler KS. 1999. Neuroticism and self-esteem as indices of the vulnerability to major depression in women. Psychol Med 29:1101-1109.
26. Rutter M, Silberg J. 2002. Gene-environment interplay in relation to emotional and behavioral disturbance. Annu Rev Psychol 53: 463-490.
27. Scher CD, Forde DR, McQuaid JR, Stein MB. 2004. Prevalence and demographic correlates of childhood maltreatment in an adult community sample. Child Abuse Negl 28:167-180.
28. Walker EA, Gelfand A, Katon WJ, Koss MP, Von KM, Bernstein D, Russo J. 1999. Adult health status of women with histories of childhood abuse and neglect. Am J Med 107:332-339.
29. Wing JK, Babor T, Brugha T, Burke J, Cooper JE, Giel R, Jablenski A, Regier D, Sartorius N. 1990. SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Arch Gen Psychiatry 47: 589-593.
30. World Health Organization. 1992. The ICD-10 classification of mental and behavioural disorders. Geneva: Author.
31. Zlotnick C, Ryan CE, Miller IW, Keitner GI. 1995. Childhood abuse and recovery from major depression. Child Abuse Negl 19: 1513-1516.