Ostreolysin affects rat aorta ring tension and endothelial cell viability in vitro

Toxicon

Volumn 49, Issue 8, 2007, Pages 1211-1213

  Rebolj, Katja ^a   Batista, Urška ^a   Sepčić, Kristina ^a   Cestnik, Vojteh ^a   Maček, Peter ^a   Frangež, Robert ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Aorta ring tension; Cardiotoxicity; Endothelial cell; Ostreolysin; Rat

Indexed keywords

CYTOLYSIN; OSTREOLYSIN; UNCLASSIFIED DRUG;

ARTICLE; CARDIOTOXICITY; CELL VIABILITY; CHINESE HAMSTER; CYTOTOXICITY; ENDOTHELIUM CELL; HUMAN; HYPERKALEMIA; LUNG FIBROBLAST; NONHUMAN; OYSTER; PRIORITY JOURNAL; UMBILICAL VEIN; VASCULAR RING;

ANIMALS; AORTA; CELL LINE; CELL SURVIVAL; CRICETINAE; CRICETULUS; ENDOTHELIAL CELLS; FUNGAL PROTEINS; HEMOLYSIN PROTEINS; HUMANS; MUSCLE TONUS; PLEUROTUS; RATS; TETRAZOLIUM SALTS; THIAZOLES;

CRICETULUS GRISEUS; OSTREA EDULIS; PLEUROTUS OSTREATUS; RATTUS;

EID: 34249005344     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2007.01.016     Document Type: Article

References (11)

1. Al-Deen I.H.S., Twaij H.A.A., Al-Badr A.A., and Istarabad T.A.W. Toxicologic and histopathologic studies of Pleurotus ostreatus mushroom in mice. J. Ethnopharm. 21 3 (1987) 297-305
2. Berne S., Križaj I., Pohleven F., Turk T., Maček P., and Sepčić K. Pleurotus and Agrocybe hemolysins, new proteins hypothetically involved in fungal fruiting. Biochim. Biophys. Acta 1570 3 (2002) 153-159
3. Berne S., Sepčić K., Anderluh G., Turk T., Maček P., and Poklar Ulrih N. Effect of pH on the pore forming activity and conformational stability of ostreolysin, a lipid raft-binding protein from the edible mushroom Pleurotus ostreatus. Biochemistry 44 33 (2005) 11137-11147
4. Boban M., Modun D., Music I., Vukovic J., Brizic I., Salamunic I., Obad A., Palada I., and Dujic Z. Red wine induced modulation of vascular function: separating the role of polyphenols, ethanol, and urates. J. Cardiovasc. Pharmacol. 47 5 (2006) 695-701
5. Freshney R.I. Culture of animal cells. A Manual of Basic Technique. fourth ed. (2000), Wiley-Liss, New York, Chichester, Weinheim, Brisbane, Singapore, Toronto
6. Kumagai T., Nagata T., Kudo Y., Fukuchi Y., Ebina K., and Yokota K. Cytotoxic activity and cytokine induction of Asp-hemolysin to vascular endothelial cells. Yakugaku Zasshi 121 4 (2001) 271-275
7. Kužner J., Drevenšek G., Geršak B., and Budihna M. Hypoxic and pharmacological preconditioning preserves vasomotor response of porcine coronary artery. Pol. J. Pharmacol. 56 6 (2004) 789-797
8. Rebolj K., Poklar Ulrih N., Maček P., and Sepčić K. Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers. Biochem. Biophys. Acta 1758 10 (2006) 1662-1670
9. Sepčić K., Berne S., Potrich C., Turk T., Maček P., and Menestrina G. Interaction of ostreolysin, a cytolytic protein from the edible mushroom Pleurotus ostreatus, with lipid membranes and modulation by lysophospholipids. Eur. J. Biochem. 270 6 (2003) 1199-1210
10. Sepčić K., Berne S., Rebolj K., Batista U., Plemenitaš A., Šentjurc M., and Maček P. Ostreolysin, a pore-forming protein from the oyster mushroom, interacts specifically with membrane cholesterol-rich lipid domains. FEBS Lett. 575 1-3 (2004) 81-85
11. Žužek M.C., Maček P., Sepčić K., Cestnik V., and Frangež R. Toxic and lethal effects of ostreolysin, a cytolytic protein from edible oyster mushroom (Pleurotus ostreatus), in rodents. Toxicon 48 3 (2006) 264-271