메뉴 건너뛰기




Volumn 5, Issue 5, 2007, Pages 1098-1109

Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; MARCKS PROTEIN; MESSENGER RNA; NUCLEAR PROTEIN; PROTEIN HMSH3; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; UNCLASSIFIED DRUG;

EID: 34248999419     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0050109     Document Type: Article
Times cited : (23)

References (38)
  • 1
    • 0032542364 scopus 로고    scopus 로고
    • Genetic instabilities in human cancers
    • Lengauer C, Kinzler KW, Vogelstein B (1998) Genetic instabilities in human cancers. Nature 396: 643-649.
    • (1998) Nature , vol.396 , pp. 643-649
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 2
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M (1993) Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 363: 558-561.
    • (1993) Nature , vol.363 , pp. 558-561
    • Ionov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 3
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau SN, Bren G, Schaid D (1993) Microsatellite instability in cancer of the proximal colon. Science 260: 816-819.
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 4
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • Kim H, Jen J, Vogelstein B, Hamilton SR (1994) Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 145: 148-156.
    • (1994) Am J Pathol , vol.145 , pp. 148-156
    • Kim, H.1    Jen, J.2    Vogelstein, B.3    Hamilton, S.R.4
  • 5
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz S, Wang J, Myeroff L, Parsons R, Sun L, et al. (1995) Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science 268: 1336-1338.
    • (1995) Science , vol.268 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3    Parsons, R.4    Sun, L.5
  • 6
    • 0038333245 scopus 로고    scopus 로고
    • Tumors with microsatellite instability: Many mutations, targets and paradoxes
    • Perucho M (2003) Tumors with microsatellite instability: Many mutations, targets and paradoxes. Oncogene 22: 2223-2225.
    • (2003) Oncogene , vol.22 , pp. 2223-2225
    • Perucho, M.1
  • 7
    • 0032529466 scopus 로고    scopus 로고
    • CD8(+) T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer
    • Naito Y, Saito K, Shiiba K, Ohuchi A, Saigenji K, et al. (1998) CD8(+) T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer. Cancer Res 58: 3491-3494.
    • (1998) Cancer Res , vol.58 , pp. 3491-3494
    • Naito, Y.1    Saito, K.2    Shiiba, K.3    Ohuchi, A.4    Saigenji, K.5
  • 8
    • 0033021439 scopus 로고    scopus 로고
    • High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability
    • Dolcetti R, Viel A, Doglioni C, Russo A, Guidoboni M, et al. (1999) High prevalence of activated intraepithelial cytotoxic T lymphocytes and increased neoplastic cell apoptosis in colorectal carcinomas with microsatellite instability. Am J Pathol 154: 1805-1813.
    • (1999) Am J Pathol , vol.154 , pp. 1805-1813
    • Dolcetti, R.1    Viel, A.2    Doglioni, C.3    Russo, A.4    Guidoboni, M.5
  • 9
    • 0036848138 scopus 로고    scopus 로고
    • The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons
    • Perrin-Vidoz L, Sinilnikova OM, Stoppa-Lyonnet D, Lenoir GM, Mazoyer S (2002) The nonsense-mediated mRNA decay pathway triggers degradation of most BRCA1 mRNAs bearing premature termination codons. Human Mol Genet 11: 2805-2814.
    • (2002) Human Mol Genet , vol.11 , pp. 2805-2814
    • Perrin-Vidoz, L.1    Sinilnikova, O.M.2    Stoppa-Lyonnet, D.3    Lenoir, G.M.4    Mazoyer, S.5
  • 10
    • 0036677083 scopus 로고    scopus 로고
    • mRNA surveillance: The perfect persist
    • Wagner E, Lykke-Andersen J (2002) mRNA surveillance: The perfect persist. J Cell Sci 115: 3033-3038.
    • (2002) J Cell Sci , vol.115 , pp. 3033-3038
    • Wagner, E.1    Lykke-Andersen, J.2
  • 11
    • 0032104190 scopus 로고    scopus 로고
    • A rule for termination-codon position within intron-containing genes: When nonsense affects RNA abundance
    • Nagy E, Maquat LE (1998) A rule for termination-codon position within intron-containing genes: When nonsense affects RNA abundance. Trends Biochem Sci 23: 198-199.
    • (1998) Trends Biochem Sci , vol.23 , pp. 198-199
    • Nagy, E.1    Maquat, L.E.2
  • 12
    • 0031840487 scopus 로고    scopus 로고
    • At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: A possible link between nuclear splicing and cytoplasmic translation
    • Zhang J, Sun XL, Qian YM, LaDuca JP, Maquat LE (1998) At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: A possible link between nuclear splicing and cytoplasmic translation. Mol Cell Biol 18: 5272-5283.
    • (1998) Mol Cell Biol , vol.18 , pp. 5272-5283
    • Zhang, J.1    Sun, X.L.2    Qian, Y.M.3    LaDuca, J.P.4    Maquat, L.E.5
  • 13
    • 0035900647 scopus 로고    scopus 로고
    • When the message goes awry: Disease-producing mutations that influence mRNA content and performance
    • Mendell JT, Dietz HC (2001) When the message goes awry: Disease-producing mutations that influence mRNA content and performance. Cell 107: 411-414.
    • (2001) Cell , vol.107 , pp. 411-414
    • Mendell, J.T.1    Dietz, H.C.2
  • 14
    • 0037422575 scopus 로고    scopus 로고
    • Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
    • Lewis BP, Green RE, Brenner SE (2003) Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans. Proc Natl Acad Sci U S A 100: 189-192.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 189-192
    • Lewis, B.P.1    Green, R.E.2    Brenner, S.E.3
  • 15
    • 26444532936 scopus 로고    scopus 로고
    • Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers
    • El-Bchiri J, Buhard O, Penard-Lacronique V, Thomas G, Hamelin R, et al. (2005) Differential nonsense mediated decay of mutated mRNAs in mismatch repair deficient colorectal cancers. Human Mol Genet 14: 2435-2442.
    • (2005) Human Mol Genet , vol.14 , pp. 2435-2442
    • El-Bchiri, J.1    Buhard, O.2    Penard-Lacronique, V.3    Thomas, G.4    Hamelin, R.5
  • 16
    • 33744994837 scopus 로고    scopus 로고
    • EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3′ UTR length
    • Buhler M, Steiner S, Mohn F, Paillusson A, Muhlemann O (2006) EJC-independent degradation of nonsense immunoglobulin-mu mRNA depends on 3′ UTR length. Nat Struct Mol Biol 13: 462-464.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 462-464
    • Buhler, M.1    Steiner, S.2    Mohn, F.3    Paillusson, A.4    Muhlemann, O.5
  • 17
    • 0032837376 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in health and disease
    • Frischmeyer PA, Dietz HC (1999) Nonsense-mediated mRNA decay in health and disease. Human Mol Genet 8: 1893-1900.
    • (1999) Human Mol Genet , vol.8 , pp. 1893-1900
    • Frischmeyer, P.A.1    Dietz, H.C.2
  • 18
    • 2442436981 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: From vacuum cleaner to Swiss army knife
    • Neu-Yilik G, Gehring NH, Hentze MW, Kulozik AE (2004) Nonsense-mediated mRNA decay: From vacuum cleaner to Swiss army knife. Genome Biol 5: 218.
    • (2004) Genome Biol , vol.5 , pp. 218
    • Neu-Yilik, G.1    Gehring, N.H.2    Hentze, M.W.3    Kulozik, A.E.4
  • 19
    • 12144285746 scopus 로고    scopus 로고
    • Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations
    • Inoue K, Khajavi M, Ohyama T, Hirabayashi S, Wilson J, et al. (2004) Molecular mechanism for distinct neurological phenotypes conveyed by allelic truncating mutations. Nat Genet 36: 361-369.
    • (2004) Nat Genet , vol.36 , pp. 361-369
    • Inoue, K.1    Khajavi, M.2    Ohyama, T.3    Hirabayashi, S.4    Wilson, J.5
  • 21
    • 33749057696 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease
    • Khajavi M, Inoue K, Lupski JR (2006) Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease. Eur J Hum Genet 14: 1074-1081
    • (2006) Eur J Hum Genet , vol.14 , pp. 1074-1081
    • Khajavi, M.1    Inoue, K.2    Lupski, J.R.3
  • 22
    • 0035895061 scopus 로고    scopus 로고
    • Congenital afibrinogenemia: Mutations leading to premature termination codons in fibrinogen A alpha-chain gene are not associated with the decay of the mutant mRNAs
    • Asselta R, Duga S, Spena S, Santagostino E, Peyvandi F, et al. (2001) Congenital afibrinogenemia: Mutations leading to premature termination codons in fibrinogen A alpha-chain gene are not associated with the decay of the mutant mRNAs. Blood 98: 3685-3692.
    • (2001) Blood , vol.98 , pp. 3685-3692
    • Asselta, R.1    Duga, S.2    Spena, S.3    Santagostino, E.4    Peyvandi, F.5
  • 23
    • 0036493774 scopus 로고    scopus 로고
    • Abnormally spliced beta-globin mRNAs: A single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay
    • Danckwardt S, Neu-Yilik G, Thermann R, Frede U, Hentze MW, et al. (2002) Abnormally spliced beta-globin mRNAs: a single point mutation generates transcripts sensitive and insensitive to nonsense-mediated mRNA decay. Blood 99: 1811-1816.
    • (2002) Blood , vol.99 , pp. 1811-1816
    • Danckwardt, S.1    Neu-Yilik, G.2    Thermann, R.3    Frede, U.4    Hentze, M.W.5
  • 24
  • 25
    • 1342325392 scopus 로고    scopus 로고
    • A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex
    • Kataoka N, Dreyfuss G (2004) A simple whole cell lysate system for in vitro splicing reveals a stepwise assembly of the exon-exon junction complex. J Biol Chem 279: 7009-7013.
    • (2004) J Biol Chem , vol.279 , pp. 7009-7013
    • Kataoka, N.1    Dreyfuss, G.2
  • 26
    • 0742323558 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics
    • Maquat LE (2004) Nonsense-mediated mRNA decay: Splicing, translation and mRNP dynamics. Nat Rev Mol Cell Biol 5: 89-99.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 89-99
    • Maquat, L.E.1
  • 27
    • 1842682946 scopus 로고    scopus 로고
    • The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex
    • Chin SY, Lejeune F, Ranganathan AC, Maquat LE (2004) The pioneer translation initiation complex is functionally distinct from but structurally overlaps with the steady-state translation initiation complex. Genes Dev 18: 745-754.
    • (2004) Genes Dev , vol.18 , pp. 745-754
    • Chin, S.Y.1    Lejeune, F.2    Ranganathan, A.C.3    Maquat, L.E.4
  • 28
    • 0035823036 scopus 로고    scopus 로고
    • Evidence for a pioneer round of mRNA translation: MRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20
    • Ishigaki Y, Li X, Serin G, Maquat LE (2001) Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell 106: 607-617.
    • (2001) Cell , vol.106 , pp. 607-617
    • Ishigaki, Y.1    Li, X.2    Serin, G.3    Maquat, L.E.4
  • 29
    • 0035823150 scopus 로고    scopus 로고
    • Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex
    • Kim VN, Kataoka N, Dreyfuss G (2001) Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex. Science 293: 1832-1836.
    • (2001) Science , vol.293 , pp. 1832-1836
    • Kim, V.N.1    Kataoka, N.2    Dreyfuss, G.3
  • 30
    • 32044435368 scopus 로고    scopus 로고
    • Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay
    • Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, et al. (2006) Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay. Genes Dev 20: 355-367.
    • (2006) Genes Dev , vol.20 , pp. 355-367
    • Kashima, I.1    Yamashita, A.2    Izumi, N.3    Kataoka, N.4    Morishita, R.5
  • 31
    • 0027993583 scopus 로고
    • Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance
    • Cheng J, Belgrader P, Zhou X, Maquat LE (1994) Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. Mol Cell Biol 14: 6317-6325.
    • (1994) Mol Cell Biol , vol.14 , pp. 6317-6325
    • Cheng, J.1    Belgrader, P.2    Zhou, X.3    Maquat, L.E.4
  • 32
    • 0032741067 scopus 로고    scopus 로고
    • Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: Implications for the control of mRNA decapping
    • Muhlrad D, Parker R (1999) Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping. Mol Biol Cell 10: 3971-3978.
    • (1999) Mol Biol Cell , vol.10 , pp. 3971-3978
    • Muhlrad, D.1    Parker, R.2
  • 33
  • 34
    • 0037064145 scopus 로고    scopus 로고
    • Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts
    • Mendell JT, ap Rhys CM, Dietz HC (2002) Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts. Science 298: 419-422.
    • (2002) Science , vol.298 , pp. 419-422
    • Mendell, J.T.1    ap Rhys, C.M.2    Dietz, H.C.3
  • 35
    • 0033373180 scopus 로고    scopus 로고
    • Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines
    • Ku JL, Yoon KA, Kim DY, Park JG (1999) Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines. Eur J Cancer 35: 1724-1729.
    • (1999) Eur J Cancer , vol.35 , pp. 1724-1729
    • Ku, J.L.1    Yoon, K.A.2    Kim, D.Y.3    Park, J.G.4
  • 36
    • 0030983076 scopus 로고    scopus 로고
    • DNA methylation and genetic instability in colorectal cancer cells
    • Lengauer C, Kinzler KW, Vogelstein B (1997) DNA methylation and genetic instability in colorectal cancer cells. Proc Natl Acad Sci U S A 94: 2545-2550.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 2545-2550
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 37
    • 0036676871 scopus 로고    scopus 로고
    • Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability
    • Kim NG, Rhee H, Li LS, Kim H, Lee JS, et al. (2002) Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability. Oncogene 21: 5081-5087.
    • (2002) Oncogene , vol.21 , pp. 5081-5087
    • Kim, N.G.1    Rhee, H.2    Li, L.S.3    Kim, H.4    Lee, J.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.