Diazinon immunotoxicity in mice: Modulation of cytokines level and their gene expression

Toxicology

Volumn 236, Issue 1-2, 2007, Pages 123-131

  Alluwaimi, Ahmed M ^a   Hussein, Yehia ^a  

^a KING FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Cytokines; Diazinon; Gene expression; IFN ; IL 2; Mice; mRNA

Indexed keywords

CYTOKINE; DIMPYLATE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 2; INTERLEUKIN 4; MESSENGER RNA; PHYTOHEMAGGLUTININ;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; CELL SUBPOPULATION; CELLULAR IMMUNITY; CONTROLLED STUDY; GENE EXPRESSION; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOREGULATION; IMMUNOTOXICITY; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; TH2 CELL;

ANIMALS; CYTOKINES; DIAZINON; GENE EXPRESSION REGULATION; INSECTICIDES; LYMPHOCYTES; MICE; RNA, MESSENGER; SPLEEN;

HEXAPODA; MUS;

EID: 34248682962     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.04.004     Document Type: Article

References (39)

1. Abd-Elnassaer M. Immunotoxic response of female Balb/c mice to diazinon, carbofuran and permethrin insecticides. Assiut. Vet. Med. J. 32 (1995) 207-215
2. Alluwaimi A.M., and Hussien Y. The effect of permethrin in the levels of IL-2 and IL-4 in mice. King Faisal Univ. Sci. J 1 (2000) 101-106
3. Alluwaimi A.M., Hussien Y., and Abu Elzein E.M. Levels of inteleukin-2 and inteleukin-4 as markers for dimethoate immunotoxicity in mice. Alex. J. Vet. Sci. 15 (1999) 703-707
4. Alluwaimi A.M., Hussien Y., and Abu Elzein E.M. Cytokine levels in mice intoxicated with diazenon. Alex. J. Vet. Sci. 17 (2001) 199-204
5. Alluwaimi, A.M., Hussien, Y., Alkhamis, M. The cytokines activity in mice model treated with Withania somnifera. King Faisal Univ. Sci. J., in press.
6. Bajgar J. Organophosphates/nerve agent poisoning: mechanism of action, diagnosis, prophylaxis, and treatment. Adv. Clin. Chem. 38 (2004) 151-216
7. Barnett J.B., Spyker-cranmer J.M., Avery D.L., and Hoberman A.M. Immunocompetence over the life span of mice exposed in utero to carbofuran or diazenon. I. Changes in serum immunoglobulin concentrations. J. Envrion. Pathol. Toxicol. 4 (1980) 53-63
8. Bullock C.D., and Johnson E.M. Nerve growth factor induces the expression of certain cytokine genes and bcl-2 in mast cells. Potential role in survival promotion. J. Biol. Chem. 271 (1996) 27500-27508
9. Castro, H.H., Gonzalez, S.R, Prat, M.I., 1994. Variation in the immune response of rabbits given food experimentally contaminated with organophsphorus insecticides. Revista De Med. Vet., Buenos Aires, 75, 255-258.
10. Ceron J.J., Sacho E., Ferando M.D., Guitierrez C., and Andreu E. Metabolic effects of diazinon on the European eel Anguilla anguilla. J. Environ. Sci. (1996)
11. Cho J.H., Park J.M., and Jean Y.H. Studies on the diagnosis of organophosphorus insecticide poisoning. Clin. Haemtol. Diagn. 31 (1989) 8-13
12. Coffey R.G., and Hadden J.W. Neurotransmitters, hormones and cyclic nucleotides in lymphocyte regulation. Fed. Proc. 44 (1985) 112-117
13. Czuminska K. The effect of bromfenwinfos in the picture of blood and lymphatic system in mice. III. The activity of lysosomal enzymes or peripheral blood lymphocytes in the states of subclinical intoxication. SGGW AR Vet. Med. 14 (1988) 101-107
14. Dunier M., Swicki A.K., and Aemael A. Effects of organophosphorus insecticides: effect of trichlorophon and dichlorvos on the immune response of carp (Cyprinus carpio). III. In vitro effects on lymphocytes proliferation and phagocytosis and In vivo effects on hummoral response. Ecotoxicol. Environ. Saf. 22 (1991) 79-87
15. Esa A.H., Warr G.A., and Newcombe D.S. Immunotoxicity of organophosphorus compounds. Modulation of cell-mediated immune responses by inhibition of monocyte accessory functions. Clin. Immunol. Immunopathol. 49 (1988) 41-52
16. Fan Q., Ding J., Zhang J., Guan N., and Deng J. Effect of the knockdown of podocin mRNA on nephrin and alpha-actinin in mouse podocyte. Exp. Biol. Med. 229 (2004) 964-970
17. Gains T.B. The acute toxicity of pesticides to rats. Toxicol. Appl. Pharmacol. 2 (1960) 88
18. Galloway T., and Handy R. Immunotoxicity of organophosphorous pesticides. Ecotoxicology 12 (2003) 345-363
19. Gushkin N.Y., Haidarova D.S., Kugusheva L.I., Rozengart V.I., and Korneva E.A. Acetylcholinesterase activity of rat lymphocytes during pesticides poisoning. Bull. Exp. Biol. Med. 111 (1991) 165-167
20. Handy R.D., Abd-El Samei H.A., Bayomy M.F., Mahran A.M., Abdeen A.M., and El-Elaimy E.A. Chronic diazinon exposure: pathologies of spleen, thymus, blood cells, and lymph nodes are modulated by dietary protein or lipid in the mouse. Toxicology 172 (2002) 13-34
21. Holsapple M.P. Developmental immunotoxicity testing. Toxicology 185 (2003) 193-203
22. Jha G.J., Mahto L.M., Tamag R.K., and Chauhan H.V. Evaluation of cell mediated immunity during chronic organophosphorus pesticide intoxication in mice and goats. Acta Vet. Hung. 38 (1990) 55-60
23. Johnsen R.E., and Hanstbarger. Handbook of Insecticides (1966), Colorado State University, Fort Collins, CO, USA
24. Kakkar B.B., Mahipal S.K., and Chauhan R.S. Effect of carbaryl and malathion on cell mediated immune response in chickens. Int. J. Anim. Sci. II (1996) 231-233
25. Khalaf-Allah S.S. Effect of pesticide water pollution on some haematological, biochemical and immunological parameters in Tilapia nilotica fish. Dtsch. Tierarztl. Wochenschr. 106 (1999) 67-71
26. Kump D.F., Matulka R.A., Burton G.F., Jordan S.D., and Holsapple M.P. Alternations in splenocyte and thymocyte subpopulations in B6C3F1 mice exposed to cocaine plus diazinon. J. Pharmacol. Exp. Ther. 277 (1996) 1477-1485
27. Matsumura F. Toxicology of Insecticides. 2nd ed. (1985), Plenum Press, NY
28. Mankame T., Hokanson R., Fudge R., Chowdhary R., and Busbee D.H. Alteration of gene expression in human cells treated with the agricultural chemical diazinon: possible interaction in fetal development. Exp. Toxicol. 25 (2006) 225-233
29. National Research Council. Drinking Water and Health vol. 1 (1977), National Academy Press, Washington DC
30. Neishabouri E.Z., Hassan Z.M., Azizi E., and Ostad S.N. Evaluation of immunotoxicity induced by diazinon in C57bl/6 mice. Toxicology 196 (2004) 173-179
31. Nigg N.H., and Knaak J.B. Blood cholinesterases as human biomarkers of organophosphorus pesticide exposure. Rev. Environ. Contam. Toxicol. 163 (2000) 29-111
32. Nomura T., Kawamura I., Tsuchiya K., Kohda C., Baba H., Ito Y., Kimoto T., Watanabe I., and Mitsuyama M. Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells. Infect. Immun. 70 (2002) 1049-1055
33. Relford R.L., Ainsworth A.J., and Harkenss J.E. Effect of a commercial malathion dip preparation on the cellular and humoral immune response of Balb/c mice. Lab. Anim. Sci. 39 (1989) 56-59
34. Rishi S., and Garg B.D. Effect of malathion on immune response to T dependent and T independent antigen in chicken. Indian J. Poult. Sci. 28 (1993) 208-216
35. Rowsey P.J., and Gordon C.J. Tumor necrosis factor is involved in chlorpyrifos-induced changes in core temperature in the female rat. Toxicol. Lett. 109 (1999) 51-59
36. Saboori A.M., Lang D.M., and Newcombe D.S. Structural requirements for the inhibition of human monocyte carboxylesterase by organophosphorus compounds. Chem. Biol. Interact. 80 (1991) 327-338
37. Stepanovic R.M., Jokanovic M., and Maksimovic M. Toxicological importance of lymphocyte neuropathy target esterase. Arch. Pharmacol. 358 (1998) 5413
38. Stiller-Winkler R., Hadnagy W., Leng G., Straube E., and Idel H. Immunological parameters in humans exposed to pesticides in the agricultural environment. Toxicol. Lett. 107 (1999) 219-224
39. WHO, 1968. Pesticide Residues Series. 5, 331.