Activin βA in term placenta and its correlation with placental inflammation in parturients having epidural or systemic meperidine analgesia: a randomized study

Journal of Clinical Anesthesia

Volumn 19, Issue 3, 2007, Pages 168-174

  Evron, Shmuel ^a,c,d   Parameswaran, Reshmi ^c   Zipori, Dov ^c   Ezri, Tiberiu ^a,d   Sadan, Oscar ^a   Koren, Rumelia ^b  

^a WOLFSON MEDICAL CENTER   (Israel)

^b HASHARON HOSPITAL   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^d UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

Activin A; analgesia; Chorioamnionitis; Epidural; Intrapartum fever; Neonatal sepsis; obstetrical; Placenta

Indexed keywords

ACTIVIN A; ANTISERUM; CEFOPERAZONE; PARACETAMOL; PETHIDINE; ROPIVACAINE; BIOLOGICAL MARKER; INHIBIN; INHIBIN BETA A SUBUNIT; NARCOTIC ANALGESIC AGENT; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BODY TEMPERATURE; CELL AGGREGATION; CELL INFILTRATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOTROPHOBLAST; DELIVERY ROOM; DISEASE ASSOCIATION; DOUBLE BLIND PROCEDURE; EPIDURAL ANESTHESIA; FEMALE; FEVER; HEALTH STATUS; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABOR INDUCTION; LABOR PAIN; LEUKOCYTE; LEUKOCYTOSIS; LYMPHOCYTE; MAJOR CLINICAL STUDY; OBSTETRIC ANALGESIA; OUTCOME ASSESSMENT; PATIENT CONTROLLED ANALGESIA; PLACENTA; PLACENTA DISORDER; PLACENTITIS; POLYMORPHONUCLEAR CELL; PRIMIPARA; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; STATISTICAL SIGNIFICANCE; SYNCYTIOTROPHOBLAST; VASCULAR ENDOTHELIUM; CHEMISTRY; CHORIOAMNIONITIS; PATHOLOGY; PREGNANCY;

ADULT; ANALGESIA, EPIDURAL; ANALGESIA, OBSTETRICAL; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; BIOLOGICAL MARKERS; CHORIOAMNIONITIS; FEMALE; FEVER; HUMANS; INHIBIN-BETA SUBUNITS; MEPERIDINE; PLACENTA; PREGNANCY; PROSPECTIVE STUDIES;

EID: 34248666978     PISSN: 09528180     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jclinane.2006.10.013     Document Type: Article

References (29)

1. Ramin S.M., Gambling D.R., Lucas M.J., Sharma S.K., Sidawi J.E., and Leveno K.J. Randomized trial of epidural versus intravenous analgesia during labor. Obstet Gynecol 86 (1995) 783-789
2. Sharma S.K., Sidawi J.E., Ramin S.M., Lucas M.J., Leveno K.J., and Cunningham F.G. Cesarean delivery: a randomized trial of epidural versus patient-controlled meperidine analgesia during labor. Anesthesiology 87 (1997) 487-494
3. Philip J., Alexander J.M., Sharma S.K., Leveno K.J., McIntire D.D., and Wiley J. Epidural analgesia during labor and maternal fever. Anesthesiology 90 (1999) 1271-1275
4. Halpern S.H., Leighton B.L., Ohlsson A., Barrett J.F., and Rice A. Effect of epidural vs parenteral opioid analgesia on the progress of labor: a meta-analysis. JAMA 280 (1998) 2105-2110
5. Camann W.R., Hortvet L.A., Hughes N., Bader A.M., and Datta S. Maternal temperature regulation during extradural analgesia for labour. Br J Anaesth 67 (1991) 565-568
6. Gonen R., Korobochka R., Degani S., and Gaitini L. Association between epidural analgesia and intrapartum fever. Am J Perinatol 17 (2000) 127-130
7. Smulian J.C., Bhandari V., Vintzileos A.M., et al. Intrapartum fever at term: serum and histologic markers of inflammation. Am J Obstet Gynecol 188 (2003) 269-274
8. Macaulay J.H., Bond K., and Steer P.J. Epidural analgesia in labor and fetal hyperthermia. Obstet Gynecol 80 (1992) 665-669
9. Fusi L., Steer P.J., Maresh M.J., and Beard R.W. Maternal pyrexia associated with the use of epidural analgesia in labour. Lancet 1 8649 (1989) 1250-1252
10. Negishi C., Lenhardt R., Ozaki M., et al. Opioids inhibit febrile responses in humans, whereas epidural analgesia does not: an explanation for hyperthermia during epidural analgesia. Anesthesiology 94 (2001) 218-222
11. Ueno N., Nishimatsu S., and Murakami K. Activin as a cell differentiation factor. Prog Growth Factor Res 2 (1990) 113-124
12. Brosh N., Sternberg D., Honigwachs-Sha'anani J., et al. The plasmacytoma growth inhibitor restrictin-P is an antagonist of interleukin 6 and interleukin 11. Identification as a stroma-derived activin A. J Biol Chem 270 (1995) 29594-29600
13. Shoham T., Yaniv E., Koren R., et al. Reduced expression of activin A in focal lymphoid agglomerates within nasal polyps. J Histochem Cytochem 49 (2001) 1245-1252
14. McClure L., O'Connor A.E., Hayward S., Jenkin G., Walker D.W., and Phillips D.J. Effects of age and pregnancy on the circulatory activin response of sheep to acute inflammatory challenge by lipopolysaccharide. J Endocrinol 185 (2005) 139-149
15. Salafia C.M., Weigl C., and Silberman L. The prevalence and distribution of acute placental inflammation in uncomplicated term pregnancies. Obstet Gynecol 73 3 Pt 1 (1989) 383-389
16. Vinson D.C., Thomas R., and Kiser T. Association between epidural analgesia during labor and fever. J Fam Pract 36 (1993) 617-622
17. Lieberman E., Lang J.M., Frigoletto Jr. F., Richardson D.K., Ringer S.A., and Cohen A. Epidural analgesia, intrapartum fever, and neonatal sepsis evaluation. Pediatrics 99 (1997) 415-419
18. Herbst A., Wolner-Hanssen P., and Ingemarsson I. Risk factors for fever in labor. Obstet Gynecol 86 (1995) 790-794
19. Frigoletto Jr. F.D., Lieberman E., Lang J.M., et al. A clinical trial of active management of labor. N Engl J Med 333 (1995) 745-750
20. Zlatnik F.J., Gellhaus T.M., Benda J.A., Koontz F.P., and Burmeister L.F. Histologic chorioamnionitis, microbial infection, and prematurity. Obstet Gynecol 76 3 Pt 1 (1990) 355-359
21. Towers C.V., Suriano K., and Asrat T. The capture rate of at-risk term newborns for early-onset group B streptococcal sepsis determined by a risk factor approach. Am J Obstet Gynecol 181 5 Pt 1 (1999) 1243-1249
22. Svensson L., Ingemarsson I., and Mardh P.A. Chorioamnionitis and the isolation of microorganisms from the placenta. Obstet Gynecol 67 (1986) 403-409
23. Dashe J.S., Rogers B.B., McIntire D.D., and Leveno K.J. Epidural analgesia and intrapartum fever: placental findings. Obstet Gynecol 93 (1999) 341-344
24. Goetzl L., Evans T., Rivers J., Suresh M.S., and Lieberman E. Elevated maternal and fetal serum interleukin-6 levels are associated with epidural fever. Am J Obstet Gynecol 187 (2002) 834-838
25. De Jongh R.F., Bosmans E.P., Puylaert M.J., Ombelet W.U., Vandeput H.J., and Berghmans R.A. The influence of anaesthetic techniques and type of delivery on peripartum serum interleukin-6 concentrations. Acta Anaesthesiol Scand 41 (1997) 853-860
26. O'Connor A.E., McFarlane J.R., Hayward S., Yohkaichiya T., Groome N.P., and de Kretser D.M. Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study. Hum Reprod 14 (1999) 827-832
27. Florio P., Luisi S., Ciarmela P., Severi F.M., Bocchi C., and Petraglia F. Inhibins and activins in pregnancy. Mol Cell Endocrinol 225 15 (2004) 93-100
28. Schneider-Kolsky M., D'Antona D., Evans L.W., et al. Maternal serum total activin A and follistatin in pregnancy and parturition. BJOG 107 (2000) 995-1000
29. Rabinovici J., Goldsmith P.C., Librach C.L., and Jaffe R.B. Localization and regulation of the activin-A dimer in human placental cells. J Clin Endocrinol Metab 75 (1992) 571-576