Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation

Hepatology

Volumn 45, Issue 5, 2007, Pages 1240-1249

  Watanabe, Natsumi ^a,b   Tanaka, Minora ^a,b   Suzuki, Kaori ^a,b   Kumanogoh, Atsushi ^b,c   Kikutani, Hitoshi ^b,c   Miyajima, Atsushi ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; IMMUNOGLOBULIN; PROTEIN TIM2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL INTERACTION; CELL MATURATION; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; LIVER CELL; LIVER DEVELOPMENT; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; T LYMPHOCYTE;

ANIMALS; CELL DIFFERENTIATION; DOWN-REGULATION; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEPATOCYTES; LIVER; MEMBRANE PROTEINS; MICE; PROTEIN SORTING SIGNALS;

EID: 34248653786     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21539     Document Type: Article

References (31)

1. Kinoshita T, Miyajima A. Cytokine regulation of liver development. Biochim Biophys Acta 2002;1592:303-312.
2. Zhao R, Duncan SA. Embryonic development of the liver. HEPATOLOGY 2005;41:956-967.
3. Jung J, Zheng M, Goldfarb M, Zaret KS. Initiation of mammalian liver development from endoderm by fibroblast growth factors. Science 1999;284:1998-2003.
4. Rossi JM, Dunn NR, Hogan BL, Zaret KS. Distinct mesodermal signals, including BMPs from rhe septum transversum mesenchyme, are required in combination for hepatogenesis from the endoderm. Genes Dev 2001;15:1998-2009.
5. Schmidt C, Bladt F, Goedecke S, Brinkmann V, Zschiesche W, Sharpe M, et al. Scatter factor/hepatocyte growth factor is essential for liver development. Nature 1995;373:699-702.
6. Kamiya A, Gonzalez FJ. TNF-alpha regulates mouse fetal hepatic maturation induced by oncostatin M and extracellular matrices. HEPATOLOGY 2004;40:527-536.
7. Kamiya A, Kinoshita T, Ito Y, Matsui T, Morikawa Y, Senba E, et al. Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer. EMBO J 1999;18:2127-2136.
8. Matsui T, Kinoshita T, Morikawa Y, Tohya K, Katsuki M, Ito Y, et al. K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development. EMBO J 2002;21:1021-1030.
9. Miyajima A, Kinoshita T, Tanaka M, Kamiya A, Mukouyama Y, Hara T. Role of Oncostatin M in hematopoiesis and liver development. Cytokine Growth Factor Rev 2000;11:177-183.
10. Tanaka M, Hirabayashi Y, Sekiguchi T, Inoue T, Katsuki M, Miyajima A. Targeted disruption of oncostatin M receptor results in altered hematopoiesis. Blood 2003;102:3154-3162.
11. Morikawa Y, Tamura S, Minehata K, Donovan PJ, Miyajima A, Senba E. Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia. J Neurosci 2004;24:1941-1947.
12. Kojima N, Kinoshita T, Kamiya A, Nakamura K, Nakashima K, Taga T, et al. Cell density-dependent regulation of hepatic development by a gp 130-independent pathway. Biochem Biophys Res Commun 2000;277:152-158.
13. Kojima T, Kitamura T. A signal sequence trap based on a constitutively active cytokine receptor. Nat Biotechnol 1999;17:487-490.
14. Tanimizu N, Nishikawa M, Saito H, Tsujimura T, Miyajima A. Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci 2003;116:1775-1786.
15. Kuchroo VK, Umetsu DT, DeKruyff RH, Freeman GJ. The TIM gene family: emerging roles in immunity and disease. Nat Rev Immunol 2003;3:454-462.
16. McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2001;2:1109-1116.
17. Umetsu SE, Lee WL, McIntire JJ, Downey L, Sanjanwala B, Akbari O, et al. TIM-1 induces T cell activation and inhibits the development of peripheral tolerance. Nat Immunol 2005;6:447-454.
18. Mesri M, Smithson G, Ghatpande A, Chapoval A, Shenoy S, Boldog F, et al. Inhibition of in vitro and in vivo T cell responses by recombinant human Tim-1 extracellular domain proteins. Int Immunol 2006;18:473-484.
19. Kumanogoh A, Marukawa S, Suzuki K, Takegahara N, Watanabe C, Ch'ng E, et al. Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature 2002;419:629-633.
20. Chakravarti S, Sabatos CA, Xiao S, Illes Z, Cha EK, Sobel RA, et al. Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med 2005;202:437-444.
21. Chen TT, Li L, Chung DH, Allen CD, Torti SV, Torti FM, et al. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J Exp Med 2005;202:955-965.
22. Rennen PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, et al. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol 2006;177:4311-4321.
23. Leonhardt J, Stanulla M, von Wasielewski R, Skokowa J, Kublet J, Ure BM, et al. Gene expression profile of the infective murine model for biliary atresia. Pediatr Surg Int 2006;22:84-89.
24. Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, et al. Hepatocyte nuclear factor 4{alpha} orchestrates expression of cell adhesion proteins duting the epithelial transformation of the developing liver. Proc Natl Acad Sci U S A 2006;103:8419-8424.
25. Nonaka H, Sugano S, Miyajima A. Serial analysis of gene expression in sinusoidal endothelial cells from normal and injured mouse liver. Biochem Biophys Res Commun 2004;324:15-24.
26. Pierce RH, Campbell JS, Stephenson AB, Franklin CC, Chaisson M, Poot M, et al. Disruption of redox homeostasis in tumor necrosis factor-induced apoptosis in a murine hepatocyte cell line. Am J Pathol 2000;157:221-236.
27. Ito Y, Matsui T, Kamiya A, Kinoshita T, Miyajima A. Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and ras pathways during hepatic development. HEPATOLOGY 2000;32:1370-1376.
28. Nakamura T, Nakayama Y, Ichihara A. Reciprocal modulation of growth and liver functions of mature rat hepatocytes in primary culture by an extract of hepatic plasma membranes. J Biol Chem 1984;259:8056-8058.
29. Knickelbein JE, de Souza AJ, Tosti R, Narayan P, Kane LP. Cutting edge: inhibition of T cell activation by TIM-2. J Immunol 2006;177:4966-4970.
30. Torti FM, Torti SV. Regulation of ferritin genes and protein. Blood 2002;99:3505-3516.
31. Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, et al. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 2004;119:529-542.