Oil-in-oil microencapsulation technique with an external perfluorohexane phase

International Journal of Pharmaceutics

Volumn 338, Issue 1-2, 2007, Pages 231-237

  Mana, Zohra ^a   Pellequer, Yann ^a   Lamprecht, Alf ^a  

^a UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

Copovidone; Eudragit RS; Microspheres; Perfluorohexane; Solvent evaporation

Indexed keywords

COPOVIDONE; EUDRAGIT; IBUPROFEN; PERFLEXANE; POVIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG FORMULATION; DRUG RELEASE; EMULSION; LIPOPHILICITY; MICROENCAPSULATION; MISCIBILITY; PARTICLE SIZE; PRIORITY JOURNAL;

ACRYLIC RESINS; EMULSIONS; FLUOROCARBONS; IBUPROFEN; MICROSPHERES; PARTICLE SIZE; POVIDONE; TECHNOLOGY, PHARMACEUTICAL;

EID: 34248635418     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.02.010     Document Type: Article

References (21)

1. Alex R., and Bodmeier R. Encapsulation of water-soluble drugs by a modified solvent evaporation method. I. Effect of process and formulation variables on drug entrapment. J. Microencaps. 7 (1989) 347-355
2. Benita S. Microencapsulation-Methods and Industrial Applications, Drugs and the Pharmaceutical Sciences vol. 73 (1996), Marcel Dekker, New York
3. Bodmeier R., and McGinity J.W. Solvent selection in the preparation of poly(dl-lactide) microspheres prepared by the solvent evaporation method. Int. J. Pharm. 43 (1988) 179-186
4. Dash A.K. Determination of the physical state of drug in microcapsule and microsphere formulations. J. Microencaps. 14 (1997) 101-112
5. Hombreiro-Perez M., Siepmann J., Zinutti C., Lamprecht A., Ubrich N., Hoffman M., Bodmeier R., and Maincent P. Non-degradable microparticles containing a hydrophilic and/or a lipophilic drug: preparation, characterization and drug release modelling. J. Controlled Release 88 (2003) 413-428
6. Jeong Y.I., Prasad Y.R., Ohno T., Yoshikawa Y., Shibata N., Kato S., Takeuchi K., and Takada K. Application of Eudragit P-4135F for the delivery of ellagic acid to the rat lower small intestine. J. Pharm. Pharmacol. 53 (2001) 1079-1085
7. ® Library - a properties database, http://www.knovel.com/knovel2/library/default.jsp.
8. Krafft M.P., and Riess J.G. Highly fluorinated amphiphiles and colloidal systems, and their applications in the biomedical field. Biochimie 80 (1998) 489-514
9. Lamprecht A., Rodero Torres H., Schäfer U., and Lehr C.M. Biodegradable microparticles as a two-drug controlled release formulation: a potential treatment of inflammatory bowel disease. J. Controlled Release 69 (2000) 445-454
10. Lamprecht A., Yamamoto H., Takeuchi H., and Kawashima Y. Design of pH-sensitive microspheres for the colonic delivery of the immunosuppressive drug tacrolimus. Eur. J. Pharm. Biopharm. 58 (2004) 37-43
11. Lorenzo-Lamosa M.L., Remunan-Lopez C., Vila-Jato J.L., and Alonso M.J. Design of microencapsulated chitosan microspheres for colonic drug delivery. J. Controlled Release 52 (1998) 109-118
12. Malamataris S., and Avgerinos A. Controlled release indomethacin microspheres prepared by using an emulsion solvent-diffusion technique. Int. J. Pharm. 62 (1990) 105-111
13. Moneghini M., Voinovich D., Princivalle F., and Magarotto L. Formulation and evaluation of vinylpyrrolidone/vinylacetate copolymer microspheres with carbamazepine. Pharm. Dev. Technol. 5 (2000) 347-353
14. Nihant N., Schugens C., Grandfils C., Jérôme R., and Teyssié P. Polylactide microparticles prepared by double emulsion:evaporation technique. I. Effect of primary emulsion stability. Pharm. Res. 11 (1994) 1479-1484
15. Nixon J.R., and Jalil R. Biodegradable poly(lactic acid) and poly (lactide-co-glycolide) microcapsules: problems associated with preparative techniques and release properties. J. Microencaps. 7 (1990) 297-325
16. Philip J., Jaykumar T., Kalyanasundaram P., Raj B., and Mondain-Monval O. Effect of polymer-surfactant association on colloidal force. Phys. Rev. E. Stat. Nonlin. Soft Matter Phys. 66 (2002) 1-8
17. Pisani E., Tsapis N., Paris J., Nicolas V., Cattel L., and Fattal E. Polymeric nano/microcapsules of liquid perfluorocarbons for ultrasonic imaging: physical characterization. Langmuir 22 (2006) 4397-4402
18. Riess J.G. Oxygen carriers ("blood substitutes")-raison d'etre, chemistry, and some physiology. Chem. Rev. 101 (2001) 2797-2920
19. Rodriguez M., Vila-Jato J.L., and Torres D. Design of a new multiparticulate system for potential site-specific and controlled drug delivery to the colonic region. J. Controlled Release 55 (1998) 67-77
20. Vojnovic D., Rubessa F., Bogataj M., and Mrhar A. Formulation and evaluation of vinylpyrrolidone/vinylacetate copolymer microspheres with griseofulvin. J. Microencaps. 10 (1993) 89-99
21. von der Hardt K., Schoff E., Kandler M.A., Dötsch J., and Rascher W. Aerosolized perfluorocarbon suppresses early pulmonary inflammatory response in a surfactant-depleted Piglet model. Pediatr. Res. 51 (2002) 177-182