Modeling of freezing step during freeze-drying of drugs in vials

AIChE Journal

Volumn 53, Issue 5, 2007, Pages 1362-1372

  Nakagawa, Kyuya ^a   Hottot, Burélie ^b   Vessot, Séverine ^b   Andrieu, Julien ^b  

^a UNIVERSITY OF HYOGO   (Japan)

^b UNIVERSITÉ LYON 1   (France)

Author keywords

Freeze drying; Freezing modeling; Ice crystal morphology; Nucleation temperature

Indexed keywords

DRYING; MASS TRANSFER; MATHEMATICAL MODELS; MECHANICAL PERMEABILITY; MORPHOLOGY; NUMERICAL METHODS; SUBLIMATION;

FREEZE-DRYING; FREEZING MODELING; ICE CRYSTAL MORPHOLOGY; NUCLEATION TEMPERATURE;

DRUG PRODUCTS;

DRUG PRODUCTS; DRYING; MASS TRANSFER; MATHEMATICAL MODELS; MECHANICAL PERMEABILITY; MORPHOLOGY; NUMERICAL METHODS; SUBLIMATION;

EID: 34248598710     PISSN: 00011541     EISSN: 15475905     Source Type: Journal    
DOI: 10.1002/aic.11147     Document Type: Article

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