Anti-angiogeneic target therapy for cancer with vaccine based on the recombinant chicken FGFR-1 in tumor-bearing mice

Journal of Huazhong University of Science and Technology - Medical Science

Volumn 27, Issue 2, 2007, Pages 120-123

  Zheng, Shaojiang ^a,b   Zheng, Shaoping ^a,b   Zhang, Junzhi ^a   Huang, Fengying ^b   Wu, Renliang ^a   Cao, Limin ^a   Xie, Mingxing ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HAINAN MEDICAL UNIVERSITY   (China)

Author keywords

Anti angiogenesis; Fibroblast growth factor receptor 1; Fibrosarcoma; Immunotherapy; Vaccine

Indexed keywords

CANCER VACCINE; RECOMBINANT PROTEIN; VASCULOTROPIN RECEPTOR 1;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CHICKEN; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROSARCOMA; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; METHODOLOGY; MOUSE; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SURVIVAL; TUMOR VOLUME; VASCULARIZATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CANCER VACCINES; CHICKENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROSARCOMA; IMMUNOTHERAPY; MICE; MICE, INBRED BALB C; NEOVASCULARIZATION, PATHOLOGIC; RECOMBINANT PROTEINS; SURVIVAL ANALYSIS; TUMOR BURDEN; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-1;

EID: 34248593067     PISSN: 16720733     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11596-007-0202-2     Document Type: Article

References (13)

1. Folkman J. Angiogenesis-dependent diseases. Semin Oncol, 2001, 28 (6):536-S42
2. Powers C J, Mcleskey S W, Wellstein A. Fibroblast growth factors, their receptors and signaling. Endocine-Related Cancer, 2000, 7:165-197
3. Klint P, Claesson-Welsh L. Signal transduction by fibro-blast growth factor receptors. Front Biosci, 1999, 15:165-177
4. Chaudhuri M M, Moscatelli D, Basilico C. Involvement of the conserved acidic amino acid domain of FGF receptor 1 in ligand-receptor interactions. J Cell Physiol, 1993, 157: 209-216
5. Valesky M, Spang A J, Fisher G W. Noninvasive dynamic fluorescence Imaging of human melanomas reveals that targeted Inhibition of bFGF or FGFR-1 in melanoma cells blocks tumor growth by apoptosis. Mol Med, 2002, 8(2): 103-111.
6. Wang F, McKeehan K, Yu C D et al. Fihroblast growth factor receptor 1 phosphotyrosine 766:molecular target for prevention of progression of prostate tumors to malignancy. Cancer Res, 2002,62(6):1898-1903
7. Udayakumar T S, Klein R D, Maliner M S et al. Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors. Int J Cancer, 2001, 91(2):187-192
8. Blanckaert V D, Venkateswaran S, Han I S et al. Partial characterization of endothelial FGF receptor functional domain by monoclonal antibody VBS-1. Hybrid Hybridomics, 2002, 21(3): 153-159
9. Roopa S, Jedd D W. Tumor antigens for cancer immuno-therapy: therapeutic potential of xenogeneic DNA vaccines. J Transl Med, 2004, 2 (1): 12-23
10. Gregor P D, Wolchok J D, Turaga V et al. Induction of autoantibodies to syngeneic prostate-specific membrane antigen by xenogeneic vaccination. Int J Cancer, 2005, 116(3):415-421
11. Zheng S J, Huang F Y, Zheng S P et al. Vaccination with a recombinant chicken FGFR-1 bypasses immunological tolerance against self-FGFR-1 in mice. J Huazhong Univ Sci Technolog [Med Sci], 2006, 26(4):389-391
12. Zheng S J, Huang F Y, Zheng S P et al. Construction and identifiction of recombinant plasmid encoding extracellular domain of FGFR1 in Chicken. J Huazhong Univer Sci Technol [Med] (Chinese), 2006,35 (4):433-435
13. Jiang H, Wu H M, Zhu P C et al. Relationship between lymphatic metastasis and expression of C-met proto- oncogene and microvessel density lung cancer. US Chin J Lymphol Oncol, 2003,2 (3):6-10