Short-term endocrine and metabolic reactions before and after second immunization against GnRH in boars

Vaccine

Volumn 25, Issue 24, 2007, Pages 4689-4696

  Claus, Rolf ^a   Lacorn, Markus ^a   Danowski, Katrin ^a   Pearce, Michael C ^b   Bauer, Aneka ^a  

^a UNIVERSITY OF HOHENHEIM   (Germany)

^b PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

Author keywords

Anamnestic vaccination; Boar sex odour; Immunological castration

Indexed keywords

ANTIBODY; GONADORELIN; IMPROVAC; LUTEINIZING HORMONE; STEROID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY TITER; ARTICLE; BLOOD ANALYSIS; BODY FAT; CASTRATION; CONTROLLED STUDY; DRUG CLEARANCE; ENDOCRINE SYSTEM; IMMUNIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN METABOLISM; SWINE; VACCINATION;

ANIMALS; ANTIBODIES; GONADOTROPIN-RELEASING HORMONE; HYDROXYPROLINE; IMMUNIZATION; INSULIN-LIKE GROWTH FACTOR I; LUTEINIZING HORMONE; MALE; SEX ATTRACTANTS; SUS SCROFA; TESTIS; TESTOSTERONE; UREA;

EID: 34248592920     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.04.009     Document Type: Article

References (48)

1. Newell J.A., and Bowland J.P. Performance, carcass composition, and fat composition of boars, gilts, and barrows fed two levels of protein. Can J Anim Sci 52 (1972) 543-551
2. Walstra P. Growth and carcass composition from birth to maturity in relation to feeding level and sex in Dutch Landrace pigs. IVO-Rep., B-160 Wageningen. Wageningen: Veenman & Zonen B.V.; 1980.
3. Campbell R.G., Taverner M.R., and Curic D.M. Effects of sex and energy intake between 48 and 90 kg live weight on protein deposition in growing pigs. Anim Prod 40 (1985) 497-503
4. Neupert B., Claus R., Herbert E., and Weiler U. Einfluss von Geschlecht, Fütterung und Lichtprogrammen auf Mastleistung und Schlachtkörperwert sowie die Androstenon- und Skatolbildung beim Schwein. Züchtungskunde 67 (1995) 317-331
5. Claus R., and Hoffmann B. Oestrogens, compared to other steroids of testicular origin, in bloodplasma of boars. Acta Endocrinol 94 (1980) 404-411
6. Snochowski M., Lundström K., Dahlberg E., Petersson H., and Edqvist L.C. Androgen and glucocorticoid receptors in porcine skeletal muscle. J Anim Sci 53 (1981) 80-90
7. Mayer M., and Rosen F. Interaction of glucocorticoids and androgens with skeletal muscle. Metabolism 26 (1977) 937-962
8. Breier B.H., Gluckman P.D., Blair H.T., and McCutcheon S.N. Somatotrophic receptors in hepatic tissue of the developing male pig. J Endocrinol 23 (1989) 25-31
9. Claus R. Bestimmung von Testosteron und 5a-Androst-16-en-3-on, einem Ebergeruchsstoff, bei Schweinen (1970), Dissertation, TU München, Germany
10. Reed H.C.B., Melrose D.R., and Patterson R.L.S. Androgen steroids as an aid to the detection of oestrus in pig artificial insemination. Br Vet J 130 (1974) 61-67
11. Patterson R.L.S. 5α-androst-16-en-3-one: compound responsible for taint in boar fat. J Sci Food Agricult 19 (1968) 31-38
12. Matthews K.R., Homer D.B., Punter P., Beague M.P., Gispert M., Kempster A.J., et al. An international study on the importance of androstenone and skatole for boar taint: III. Consumer survey in seven European countries. Meat Sci 54 (2000) 271-283
13. Daxenberger A., Hageleit M., Kraetzl W.-D., Lange I.G., Claus R., Le Bizec B., et al. Suppression of androstenone in entire male pigs by anabolic preparations. Livest Prod Sci 69 (2001) 139-144
14. Grizzle T.B., Esbenshade K.L., and Johnson B.H. Active immunization of boars against gonadotropin releasing hormone. I. Effects on reproductive parameters. Theriogenology 27 (1987) 571-580
15. Bonneau M., Dufour R., Chouvet C., Roulet C., Meadus W., and Squires E.J. The effects of immunization against luteinizing hormone-releasing hormone on performance, sexual development, and levels of boar taint-related compounds in intact male pigs. J Anim Sci 72 (1994) 14-20
16. Oonk H.B., Turkstra J.A., Lankhof H., Schaaper W.M., Verheijden J.H.M., and Meloen R.H. Testis size after immunocastration as parameter for the absence of boar taint. Livest Prod Sci 42 (1995) 63-71
17. Hennessy D.P., Colantoni C., Dunshea F.R., Howard K., Jackson P., Long K., et al. Elimination of boar taint: a commercial boar taint vaccine for male pigs vol. 92 (1997), EAAP Publication pp. 141-144
18. Dunshea F.R., Colantoni C., Howard K., McCauley I., Jackson P., Long K.A., et al. Vaccination of boars with a GnRH vaccine (Improvac) eliminates boar taint and increases growth performance. J Anim Sci 79 (2001) 2524-2535
19. Metz C., Hohl K., Waidelich S., Drochner W., and Claus R. Active immunization of boars against GnRH at an early age: consequences for testicular function, boar taint accumulation and N-retention. Livest Prod Sci 74 (2002) 147-157
20. Claus R. Messung des Ebergeruchsstoffes im Fett von Schweinen mittels eines Radioimmuntests. 2. Mitteilung: Zeitlicher Verlauf des Geruchsdepotabbaues nach der Kastration. Ztschr Tierzücht Züchtungsbiol 93 (1976) 38-47
21. Claus R., Bingel A., Hofäcker S., and Weiler U. Twenty-four hour profiles of growth hormone (GH) concentrations in mature female and entire male domestic pigs in comparison to mature wild boars (sus scrofa L). Livest Prod Sci 25 (1990) 247-255
22. Wagner A., and Claus R. Involvement of glucocorticoids in testicular involution after active immunization in boars against GnRH. Reproduction 127 (2004) 275-283
23. Bubenik G.A., Morris J.M., Schams D., and Claus R. Photoperiodicity and circannual levels of LH, FSH and testosterone in normal and castrated male, white-tailed deer. Can J Physiol Pharmacol 60 (1982) 788-793
24. Claus R., Weiler U., Hofäcker S., Herzog A., and Meng H. Cycle dependent changes of growth hormone (GH), insulin-like growth factor I (IGF-1) and insulin in bloodplasma of sows and their relation to progesterone and oestradiol. Growth Regulat 2 (1992) 115-121
25. Lopes S., Claus R., Lacorn M., Wagner A., and Mosenthin R. Effects of dexamethasone application in growing pigs on hormones, N-retention and metabolic parameters. J Vet Med A 51 (2004) 97-105
26. 2O bestimmten Körperwasser. Ph.D. thesis. Germany: University of Hohenheim; 1984.
27. Tissier M., Robelin J., Purroy A., and Geay Y. Extraction et dosage automatique rapide de l'eau lourde dans les liquides biologiques. Ann Biol Anim Bioch Biophys 18 (1978) 1223-1228
28. Waterlow J.C., Garlick P.J., and Millward D.J. Protein turnover in mammalian tissues and in the whole body (1978), Elsevier/North-Holland Biomedical Press, Amsterdam, The Netherlands
29. Einarsson S. Selective determination of secondary amino acids using precolumn derivatization with 9-fluorenylmethylchloroformate and reversed-phase high-performance liquid chromatography. J Chromatogr 348 (1985) 213-220
30. Sachs L. Angewandte Statistik. 7th ed. (1992), Springer, Berlin
31. Brooks R.I., Pearson A.M., Hogberg M.G., Pestka J.J., and Gray J.I. An immunological approach for prevention of boar odor in pork. J Anim Sci 62 (1986) 1279-1289
32. Roitt I.M., and Delves P.J. Roitt's essential immunology. 10th ed. (2001), Blackwell Science, Oxford
33. Oonk H.B., Turkstra J.A., Schaaper W.M., Erkens M., Schuitemaker-de Weerd M.H., van Nes A., et al. New GnRH-like peptide construct to optimize efficient immunocastration of male pigs by immunoneutralization of GnRH. Vaccine 16 (1998) 1074-1082
34. Turkstra J.A., Oonk H.B., Schaaper W.M.M., and Meloen R.H. The role of individual amino acids of a GnRH tandem dimer peptide used as antigen for immunocastration of male piglets determined with systematic alanine replacements. Vaccine 20 (2002) 406-412
35. Turkstra J.A., Zeng X.Y., van Diepen JThM, Jongbloed A.W., Oonk H.B., van de Wiel D.F.M., et al. Performance of male pigs immunized against GnRH is related to the time of onset of biological response. J Anim Sci 80 (2002) 2953-2959
36. Schwarzenberger F., Tode G.S., Christie H.L., and Raeside J.I. Plasma levels of several androgens and estrogens from birth to puberty in male domestic pigs. Acta Endocrinol 128 (1993) 173-177
37. Franca L.R., Silva V.A., Chiarini-Garcia H., Garcia S.K., and Debeljuk L. Cell proliferation and hormonal changes during postnatal development of the testis in the pig. Biol Reprod 63 (2000) 1629-1636
38. Claus R. Messung des Ebergeruchstoffes im Fett von Schweinen mittels eines Radioimmunotests. 1. Mitteilung: Geruchsdepotbildung in Abhängigkeit vom Alter. Ztschr Tierzücht Züchtungsbiol 92 (1975) 118-126
39. Lunstra D.D., Ford J.J., Klindt J., and Wise T.H. Physiology of the Meishan boar. J Reprod Fert Suppl 52 (1997) 181-193
40. Voutilainen R., Tapanainen J., Chung B.C., Mattheson K.J., and Miller W.L. Hormonal regulation of p450scc (20,22-desmolase) and p450c17 (17-alpha-hydroxylase/17,20-lyase) in cultured human granulosa cells. J Endocrinol Metab 63 (1986) 202-207
41. Payne A.H. Hormonal regulation of cytochrome P450 enzymes, cholesterol side-chain deavage and 17-alpha-hydroxylase/C17-20lyase in Leydig cells. Biol Reprod 42 (1990) 399-404
42. Claus R., Münch U., Nagel S., and Schopper D. Concentrations of 17ß-oestradiol, oestrone and testosterone in tissues of slaughterweight boars compared to barrows and gilts. Arch Lebensmittelhyg 40 (1989) 123-126
43. Claus R. Pheromone bei Säugetieren unter besonderer Berücksichtigung des Ebergeruchsstoffes und seiner Beziehung zu anderen Hodensteroiden. Beiheft 10: Fortschritte in der Tierphysiologie und Tierernährung (1979), Paul Parey, Hamburg und Berlin pp. 1-136
44. Claus R., Weiler U., and Herzog A. Physiological aspects of androstenone and skatole formation in the boar: a review with experimental data. Meat Sci 38 (1994) 289-305
45. Zhou R., Diehl D., Hoeflich A., Lahm H., and Wolf E. IGF-binding protein-4: biochemical characteristics and functional consequences. J Endocrinol 178 (2003) 177-193
46. Miller L.F., Judge M.D., and Schanbacher B.D. Intramuscular collagen and serum hydroxyproline as related to implanted testosterone, dihydrotestosterone and estradiol-17ß in growing wethers. J Anim Sci 68 (1990) 1044-1048
47. Nold R.A., Romans J.R., Costello W.J., and Lival G.W. Characterization of muscles from boars, barrows, and gilts slaughtered at 100 or 110 kilograms: differences in fat, moisture, color, water-holding capacity, and collagen. J Anim Sci 77 (1999) 1746-1754
48. Claus R., and Weiler U. Umwelteinflüsse auf das geschlechtsspezifische Wachstumsvermögen. Übers Tierern 15 (1987) 301-316