-
1
-
-
0026474338
-
Determination of self-association of irinotecan hydrochloride (CPT-11) in aqueous solution
-
Aiyama R., Nagai H., Sawasa S., Yokokura T., Itokawa H., and Nakanishi M. Determination of self-association of irinotecan hydrochloride (CPT-11) in aqueous solution. Chem. Pharm. Bull. 40 (1992) 2810-2813
-
(1992)
Chem. Pharm. Bull.
, vol.40
, pp. 2810-2813
-
-
Aiyama, R.1
Nagai, H.2
Sawasa, S.3
Yokokura, T.4
Itokawa, H.5
Nakanishi, M.6
-
3
-
-
0141601905
-
Novel procedures for generating and loading liposomal systems
-
Gregoriadis G. (Ed), John Wiley & Sons Ltd.
-
Bally M.B., Hope M.J., Mayer L.D., Madden T.D., and Cullis P.R. Novel procedures for generating and loading liposomal systems. In: Gregoriadis G. (Ed). Liposomes as Drug Carriers (1988), John Wiley & Sons Ltd. 841-853
-
(1988)
Liposomes as Drug Carriers
, pp. 841-853
-
-
Bally, M.B.1
Hope, M.J.2
Mayer, L.D.3
Madden, T.D.4
Cullis, P.R.5
-
4
-
-
0027196444
-
Stability of liposomal doxorubicin formulations: problems and prospects
-
Barenholz Y., Amselem S., Goren D., Cohen R., Gelvan D., Samuni A., Golden E.B., and Gabizon A. Stability of liposomal doxorubicin formulations: problems and prospects. Med. Res. Rev. 13 (1993) 449-491
-
(1993)
Med. Res. Rev.
, vol.13
, pp. 449-491
-
-
Barenholz, Y.1
Amselem, S.2
Goren, D.3
Cohen, R.4
Gelvan, D.5
Samuni, A.6
Golden, E.B.7
Gabizon, A.8
-
5
-
-
34248558800
-
Phase I study of CPX-1, a fixed ratio formulation of irinotecan (Iri) and floxuridine (Flox), in patients with advanced solid tumors
-
(Abstract No. 2014)
-
Batist G., Chi K., Miller W., Chia S., Hasanbasic F., Fisic A., Mayer L.M., Swenson C., Janoff A., and Gelmon K. Phase I study of CPX-1, a fixed ratio formulation of irinotecan (Iri) and floxuridine (Flox), in patients with advanced solid tumors. Proceedings of the 2006 ASCO Annual Meeting (2006) (Abstract No. 2014)
-
(2006)
Proceedings of the 2006 ASCO Annual Meeting
-
-
Batist, G.1
Chi, K.2
Miller, W.3
Chia, S.4
Hasanbasic, F.5
Fisic, A.6
Mayer, L.M.7
Swenson, C.8
Janoff, A.9
Gelmon, K.10
-
6
-
-
0024291319
-
13C{double bond, long}O-labeled phospholipids hydrogen bonding to carbonyl groups
-
13C{double bond, long}O-labeled phospholipids hydrogen bonding to carbonyl groups. Biochemistry 27 (1988) 8239-8249
-
(1988)
Biochemistry
, vol.27
, pp. 8239-8249
-
-
Blume, A.1
Hubner, W.2
Messner, G.3
-
7
-
-
0027433668
-
Optimization of the retention properties of vincristine in liposomal systems
-
Boman N.L., Mayer L.D., and Cullis P.R. Optimization of the retention properties of vincristine in liposomal systems. Biochim. Biophys. Acta 1152 (1993) 253-258
-
(1993)
Biochim. Biophys. Acta
, vol.1152
, pp. 253-258
-
-
Boman, N.L.1
Mayer, L.D.2
Cullis, P.R.3
-
8
-
-
0345382806
-
Role of radicals and singlet oxygen in photoactivated DNA cleavage by the anticancer drug camptothecin: an electron paramagnetic resonance study
-
Brezova V., Valko M., Breza M., Morris H., Telser J.m., Dvoranova D., Kaiserova K., Varecka L., Mazur M., and Leibfritz D. Role of radicals and singlet oxygen in photoactivated DNA cleavage by the anticancer drug camptothecin: an electron paramagnetic resonance study. J. Phys. Chem. B 107 (2003) 2415-2425
-
(2003)
J. Phys. Chem. B
, vol.107
, pp. 2415-2425
-
-
Brezova, V.1
Valko, M.2
Breza, M.3
Morris, H.4
Telser, J.m.5
Dvoranova, D.6
Kaiserova, K.7
Varecka, L.8
Mazur, M.9
Leibfritz, D.10
-
9
-
-
0027276081
-
Lipid bilayer partitioning and stability of camptothecin drugs
-
Burke T.G., Mishra A.K., Wani M.C., and Wall M.E. Lipid bilayer partitioning and stability of camptothecin drugs. Biochemistry 32 (1993) 5352-5364
-
(1993)
Biochemistry
, vol.32
, pp. 5352-5364
-
-
Burke, T.G.1
Mishra, A.K.2
Wani, M.C.3
Wall, M.E.4
-
11
-
-
0032473430
-
Kinetics of lactone hydrolysis in antitumor drugs of camptothecin series as studied by fluorescence spectroscopy
-
Chourpa I., Millot J.-M., Sockalingum G.D., Riou J.-F., and Manfait M. Kinetics of lactone hydrolysis in antitumor drugs of camptothecin series as studied by fluorescence spectroscopy. Biochim. Biophys. Acta 1379 (1998) 353-366
-
(1998)
Biochim. Biophys. Acta
, vol.1379
, pp. 353-366
-
-
Chourpa, I.1
Millot, J.-M.2
Sockalingum, G.D.3
Riou, J.-F.4
Manfait, M.5
-
12
-
-
0027330906
-
Phase I and pharmacokinetic trial of liposome-encapsulated doxorubicin
-
Conley B.A., Egorin M.J., Whitacre M.Y., Carter D.C., Zuhowski E.G., and Van Echo D.A. Phase I and pharmacokinetic trial of liposome-encapsulated doxorubicin. Cancer Chemother. Pharmacol. 33 (1993) 107-112
-
(1993)
Cancer Chemother. Pharmacol.
, vol.33
, pp. 107-112
-
-
Conley, B.A.1
Egorin, M.J.2
Whitacre, M.Y.3
Carter, D.C.4
Zuhowski, E.G.5
Van Echo, D.A.6
-
13
-
-
34248542161
-
pH gradients and membrane transport in liposomal systems
-
Cullis P.R., Bally M.B., Madden T.D., Mayer L.D., and Hope M.J. pH gradients and membrane transport in liposomal systems. Tibtech. 9 (1991) 57-61
-
(1991)
Tibtech.
, vol.9
, pp. 57-61
-
-
Cullis, P.R.1
Bally, M.B.2
Madden, T.D.3
Mayer, L.D.4
Hope, M.J.5
-
14
-
-
0030886615
-
Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles
-
Cullis P.R., Hope M.J., Bally M.B., Madden T.D., Mayer L.D., and Fenske D.B. Influence of pH gradients on the transbilayer transport of drugs, lipids, peptides and metal ions into large unilamellar vesicles. Biochim. Biophys. Acta 1331 (1997) 187-211
-
(1997)
Biochim. Biophys. Acta
, vol.1331
, pp. 187-211
-
-
Cullis, P.R.1
Hope, M.J.2
Bally, M.B.3
Madden, T.D.4
Mayer, L.D.5
Fenske, D.B.6
-
15
-
-
33645047575
-
Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy
-
Drummond D.C., Noble C.O., Guo Z., Hong K., Park J.W., and Kirpotin D.B. Development of a highly active nanoliposomal irinotecan using a novel intraliposomal stabilization strategy. Cancer Res. 66 (2006) 2171-3277
-
(2006)
Cancer Res.
, vol.66
, pp. 2171-3277
-
-
Drummond, D.C.1
Noble, C.O.2
Guo, Z.3
Hong, K.4
Park, J.W.5
Kirpotin, D.B.6
-
16
-
-
0001174442
-
Complexes of Cu(II) with d-aldonic and d-alduronic acids in aqueous solution
-
Escandar G.M., and Sala L.F. Complexes of Cu(II) with d-aldonic and d-alduronic acids in aqueous solution. Can. J. Chem. 70 (1992) 2053-2057
-
(1992)
Can. J. Chem.
, vol.70
, pp. 2053-2057
-
-
Escandar, G.M.1
Sala, L.F.2
-
17
-
-
0033624738
-
Spectroscopic studies of copper(II) and iron(II) complexes of adriamycin
-
Feng M., Yang Y., He P., and Fang Y. Spectroscopic studies of copper(II) and iron(II) complexes of adriamycin. Spectrochim. Acta A 56 (2000) 581-587
-
(2000)
Spectrochim. Acta A
, vol.56
, pp. 581-587
-
-
Feng, M.1
Yang, Y.2
He, P.3
Fang, Y.4
-
18
-
-
0002829160
-
Role of metal-binding in the biological activities of drugs
-
Foye W.O. Role of metal-binding in the biological activities of drugs. J. Pharm. Sci. 50 (1961) 93-108
-
(1961)
J. Pharm. Sci.
, vol.50
, pp. 93-108
-
-
Foye, W.O.1
-
19
-
-
0001100455
-
Coordination chemistry of polyhydroxy acids: role of the hydroxyl groups
-
Gajda T., Gyurcsik B., Jakusch T., Burger K., Henry B., and Delpuech J.-J. Coordination chemistry of polyhydroxy acids: role of the hydroxyl groups. Inorg. Chim. Acta 275-276 (1998) 130-140
-
(1998)
Inorg. Chim. Acta
, vol.275-276
, pp. 130-140
-
-
Gajda, T.1
Gyurcsik, B.2
Jakusch, T.3
Burger, K.4
Henry, B.5
Delpuech, J.-J.6
-
20
-
-
0032974761
-
Phase I study of liposomal vincristine
-
Gelmon K.A., Tolcher A., Diab A.R., Bally M.B., Embree L., Hudon N., Dedhar C., Ayers D., Eisen A., Melosky B., Burge C., Logan P., and Mayer L.D. Phase I study of liposomal vincristine. J. Clin. Oncol. 17 (1999) 697-705
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 697-705
-
-
Gelmon, K.A.1
Tolcher, A.2
Diab, A.R.3
Bally, M.B.4
Embree, L.5
Hudon, N.6
Dedhar, C.7
Ayers, D.8
Eisen, A.9
Melosky, B.10
Burge, C.11
Logan, P.12
Mayer, L.D.13
-
21
-
-
0020284633
-
The binding of copper ions to daunomycin and adriamycin
-
Greenaway F.T., and Dabrowiack J.C. The binding of copper ions to daunomycin and adriamycin. J. Inorg. Biochem. 16 (1982) 91-107
-
(1982)
J. Inorg. Biochem.
, vol.16
, pp. 91-107
-
-
Greenaway, F.T.1
Dabrowiack, J.C.2
-
22
-
-
0027377645
-
Chemical stability of liposomes: implications for their physical stability
-
Grit M., and Crommelin D.J. Chemical stability of liposomes: implications for their physical stability. Chem. Phys. Lipids 64 (1993) 3-18
-
(1993)
Chem. Phys. Lipids
, vol.64
, pp. 3-18
-
-
Grit, M.1
Crommelin, D.J.2
-
23
-
-
0027514941
-
Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases
-
Haran G., Cohen R., Bar L.K., and Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta 1151 (1993) 201-215
-
(1993)
Biochim. Biophys. Acta
, vol.1151
, pp. 201-215
-
-
Haran, G.1
Cohen, R.2
Bar, L.K.3
Barenholz, Y.4
-
24
-
-
0027050420
-
Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma
-
Huang S.K., Mayhew E., Gilani S., Lasic D.D., Martin F.J., and Papahadjopoulos D. Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. Cancer Res. 52 (1992) 6774-6781
-
(1992)
Cancer Res.
, vol.52
, pp. 6774-6781
-
-
Huang, S.K.1
Mayhew, E.2
Gilani, S.3
Lasic, D.D.4
Martin, F.J.5
Papahadjopoulos, D.6
-
25
-
-
0022551382
-
Photosensitive DNA cleavage and phage inactivation by copper(II)-camptothecin
-
Kuwahara J., Suzuki T., Funakoshi F., and Sugiura Y. Photosensitive DNA cleavage and phage inactivation by copper(II)-camptothecin. Biochemistry 25 (1986) 1216-1221
-
(1986)
Biochemistry
, vol.25
, pp. 1216-1221
-
-
Kuwahara, J.1
Suzuki, T.2
Funakoshi, F.3
Sugiura, Y.4
-
26
-
-
0025278891
-
The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey
-
Madden T.D., Harrigan P.R., Tai L.C.L., Bally M.B., Mayer L.D., Redelmeier T.E., Loughrey H.C., Tilcock C.P.S., Reinish L.W., and Cullis P.R. The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey. Chem. Phys. Lipids 53 (1990) 37-46
-
(1990)
Chem. Phys. Lipids
, vol.53
, pp. 37-46
-
-
Madden, T.D.1
Harrigan, P.R.2
Tai, L.C.L.3
Bally, M.B.4
Mayer, L.D.5
Redelmeier, T.E.6
Loughrey, H.C.7
Tilcock, C.P.S.8
Reinish, L.W.9
Cullis, P.R.10
-
27
-
-
0021829850
-
Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential
-
Mayer L.D., Bally M.B., Hope M.J., and Cullis P.R. Uptake of antineoplastic agents into large unilamellar vesicles in response to a membrane potential. Biochim. Biophys. Acta 813 (1985) 294-302
-
(1985)
Biochim. Biophys. Acta
, vol.813
, pp. 294-302
-
-
Mayer, L.D.1
Bally, M.B.2
Hope, M.J.3
Cullis, P.R.4
-
28
-
-
0024470863
-
Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice
-
Mayer L.D., Tai L.C.L., Ko D.S.C., Masin D., Ginsberg R.S., Cullis P.R., and Bally M.B. Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice. Cancer Res. 49 (1989) 5922-5930
-
(1989)
Cancer Res.
, vol.49
, pp. 5922-5930
-
-
Mayer, L.D.1
Tai, L.C.L.2
Ko, D.S.C.3
Masin, D.4
Ginsberg, R.S.5
Cullis, P.R.6
Bally, M.B.7
-
29
-
-
33748326024
-
Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration dictates therapeutic activity in tumor-bearing mice
-
Mayer L.D., Harasym T.O., Tardi P.G., Harasym N.L., Shew C.R., Johnstone S.A., Ramsay E.C., Bally M.B., and Janoff A.S. Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration dictates therapeutic activity in tumor-bearing mice. Mol. Cancer Ther. 5 (2006) 1854-1863
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 1854-1863
-
-
Mayer, L.D.1
Harasym, T.O.2
Tardi, P.G.3
Harasym, N.L.4
Shew, C.R.5
Johnstone, S.A.6
Ramsay, E.C.7
Bally, M.B.8
Janoff, A.S.9
-
30
-
-
0032523144
-
Spectroscopic and biochemical characterization of self-aggregates formed by antitumor drugs of the camptothecin family
-
Nabiev I., Fleury F., Kudelina I., Pommier Y., Charton F., Riou J.-F., Alix A.J., and Manfait M. Spectroscopic and biochemical characterization of self-aggregates formed by antitumor drugs of the camptothecin family. Biochem. Pharmacol. 55 (1998) 1163-1174
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 1163-1174
-
-
Nabiev, I.1
Fleury, F.2
Kudelina, I.3
Pommier, Y.4
Charton, F.5
Riou, J.-F.6
Alix, A.J.7
Manfait, M.8
-
31
-
-
33645049055
-
Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy
-
Noble C.O., Krauze M.T., Drummond D.C., Yamashita Y., Saito R., Berger M.S., Kirpotin D.B., Bankiewicz K.S., and Park J.W. Novel nanoliposomal CPT-11 infused by convection-enhanced delivery in intracranial tumors: pharmacology and efficacy. Cancer Res. 66 (2006) 2801-2806
-
(2006)
Cancer Res.
, vol.66
, pp. 2801-2806
-
-
Noble, C.O.1
Krauze, M.T.2
Drummond, D.C.3
Yamashita, Y.4
Saito, R.5
Berger, M.S.6
Kirpotin, D.B.7
Bankiewicz, K.S.8
Park, J.W.9
-
32
-
-
33748320192
-
A novel approach to prepare a liposomal irinotecan formulation that exhibit significant therapeutic activity in vivo
-
(abstract #639)
-
Ramsay E., Alnajim J., Anantha M., Dicko A., Harvie P., Mayer L.D., Bally M.B., and Tardi P. A novel approach to prepare a liposomal irinotecan formulation that exhibit significant therapeutic activity in vivo. Proc. Annu. Meet. Am. Assoc. Cancer Res. 45 (2004) (abstract #639)
-
(2004)
Proc. Annu. Meet. Am. Assoc. Cancer Res.
, vol.45
-
-
Ramsay, E.1
Alnajim, J.2
Anantha, M.3
Dicko, A.4
Harvie, P.5
Mayer, L.D.6
Bally, M.B.7
Tardi, P.8
-
34
-
-
0023191274
-
EPR studies of copper(II) and cobalt(II) complexes of adriamycin
-
Tachibana M., Iwaizumi M., and Tero-Kubota S. EPR studies of copper(II) and cobalt(II) complexes of adriamycin. J. Inorg. Biochem. 30 (1987) 133-140
-
(1987)
J. Inorg. Biochem.
, vol.30
, pp. 133-140
-
-
Tachibana, M.1
Iwaizumi, M.2
Tero-Kubota, S.3
-
35
-
-
34248558799
-
-
Tardi, P.G., Gallagher, R.C., Johnson, S., Harasym, N., Webb, M., Bally, M.B., Mayer, L.D., in press. Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo. Biochim. Biophys. Acta.
-
-
-
-
36
-
-
4444328891
-
3N,O,O′)copper(II) squarate
-
3N,O,O′)copper(II) squarate. Acta Crystallogr. E60 (2004) m322-m324
-
(2004)
Acta Crystallogr.
, vol.E60
-
-
Ucar, I.1
Yesilel, O.Z.2
Bulut, A.3
Icbudak, H.4
Olmez, H.5
Kazak, C.6
-
37
-
-
0033515029
-
Copper binding to the prion protein: structural implications of four identical cooperative binding sites
-
Viles J.H., Cohen F.E., Prusiner S.B., Goodin D.B., Wright P.E., and Dyson H.J. Copper binding to the prion protein: structural implications of four identical cooperative binding sites. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 2042-2047
-
(1999)
Proc. Natl. Acad. Sci. U.S.A.
, vol.96
, pp. 2042-2047
-
-
Viles, J.H.1
Cohen, F.E.2
Prusiner, S.B.3
Goodin, D.B.4
Wright, P.E.5
Dyson, H.J.6
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