Determination of ghrelin immunoreactivity in the rat stomach after fasting and refeeding

Acta Histochemica

Volumn 109, Issue 3, 2007, Pages 193-199

  Sönmez, Mehmet Fatih ^a   Ozan, Enver ^b  

^a ERCIYES UNIVERSITY   (Turkey)

^b FIRAT UNIVERSITY   (Turkey)

Author keywords

Fasting; Ghrelin; Immunohistochemistry; Rats; Stomach

Indexed keywords

CELLS; DIGESTIVE SYSTEM; HORMONES; NUTRITION; TISSUE;

FASTING; GHRELIN; IMMUNOHISTOCHEMISTRY; STOMACH;

RATS;

GHRELIN;

ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; EXPERIMENTAL STUDY; HORMONE DETERMINATION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; RAT; REFEEDING; STOMACH EPITHELIUM; STOMACH MUCOSA; TISSUE PRESERVATION;

RATTUS; RATTUS NORVEGICUS;

EID: 34248580617     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2007.02.002     Document Type: Article

References (36)

1. Asakawa A., Inui A., Kaga T., Yuzuriha H., Nagata T., Ueno N., et al. Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin. Gastroenterology 120 (2001) 337-345
2. Bordi C., D'Adda T., Azzoni C., and Ferarro G. Classification of gastric endocrine cells at the light and electron microscopical levels. Microsc Res Technol 48 (2000) 258-271
3. Date Y., Kojima M., Hosoda H., Sawaguchi A., Mondal M.S., Suganuma T., et al. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 141 (2000) 4255-4261
4. Dornonville de la Cour C., Bjorkqvist M., Sandvik A.K., Bakke I., Zhao C.M., Chen D., et al. A-like cells in the rat stomach contain ghrelin and do not operate under gastrin control. Regul Pept 99 (2001) 141-150
5. Gehlert D.R. Role of hypothalamic neuropeptide Y in feeding and obesity. Neuropeptides 33 (1999) 329-338
6. Gomez G., Englander E.W., and Greeley Jr. G.H. Nutrient inhibition of ghrelin secretion in the fasted rat. Regul Pept 117 (2004) 33-36
7. Govoni N., De Iasio R., Cocco C., Parmeggiani A., Galeati G., Pagotto U., et al. Gastric immunolocalization and plasma profiles of acyl-ghrelin in fasted and fasted-refed prepuberal gilts. J Endocrinol 186 (2005) 505-513
8. Guillermo G., Ella W.E., and George H.G. Nutritient inhibition of ghrelin secretion in the fasted rat. Regul Pept 117 (2004) 33-36
9. Gültekin H., Şahin S., and Budak N. Beslenme davrani{dotless}şi{dotless}: farmakolojik hedef moleküller. Journal of Health Science 13 (2004) 77-87
10. Hewson A.K., and Dickson S.L. Systemic administration of ghrelin induces Fos and Egr-1 proteins in the hypothalamic arcuate nucleus of fasted and fed rats. J Neuroendocrinol 12 (2000) 1047-1049
11. Hosoda H., Kojima M., Matsuo H., and Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun 279 (2000) 909-913
12. Inui A. Ghrelin: an orexigenic and somatotrophic signal from the stomach. Nat Rev Neurosci 2 (2001) 551-560
13. Kalra S.P., Dube M.G., Pu S., Xu B., Horvath T.L., and Kalra P.S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20 (1999) 68-100
14. Kim M.S., Yoon C.Y., Park K.H., Shin C.S., Park K.S., Kim S.Y., et al. Changes in ghrelin and ghreli receptor expression according to feeding status. Neuroreport 14 (2003) 1317-1320
15. Kojima M., and Kangawa K. Ghrelin: a novel growth-hormone releasing peptide. Nippon Rinsho 59 (2001) 1400-1407
16. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., and Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402 (1999) 656-660
17. Kojima M., Hosoda H., Matsuo H., and Kangawa K. Ghrelin: discovery of the natural endogenous ligand for the growth hormone secretagogue receptor. Trends Endocrinol Metab 12 (2001) 118-122
18. Moesgaard S.G., Ahren B., Carr R.D., Gram D.X., Brand C.L., and Sundler F. Effects of high-fat feeding and fasting on ghrelin expression in the mouse stomach. Regul Pept 120 (2004) 261-267
19. Muccioli G., Tschop M., Papotti M., Deghenghi R., Heiman M., and Ghigo E. Neuroendocrine and peripheral activities of ghrelin: implications in metabolism and obesity. Eur J Pharmacol 440 (2002) 235-254
20. Nakazato M., Murakami N., Date Y., et al. A role for ghrelin in the central regulation of feeding. Nature 409 (2001) 194-198
21. Neglia S., Arcamone N., Esposito V., Gargiulo G., and de Girolamo P. Presence and distribution of ghrelin-immunopositive cells in the chicken gastrointestinal tract. Acta Histochem 107 (2005) 3-9
22. Nieminen P., Mustonen A.M., and Hyvarinen H. Fasting reduces plasma leptin-and ghrelin-immunoreactive peptide concentrations of the burbot (Lota lota) at 2 degrees C but not at 10 degrees C. Zool Sci 20 (2003) 1109-1115
23. Otto B., Cuntz U., Fruehauf E., et al. Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur J Endocrinol 145 (2002) 669-673
24. Rindi G., Necchi V., Savio A., Torsello A., Zoli M., Locatelli V., et al. Characterisation of gastric ghrelin cells in man and other mammals: studies in adult and fetal tissues. Histochem Cell Biol 117 (2002) 511-519
25. Sakata I., Nakamura K., Yamazaki M., Hayashi Y., and Kangawa K. Ghrelin-producing cells exist as two types of cells, closed and opened-type cells, in the rat gastrointestinal tract. Peptides 23 (2002) 531-536
26. Sakata I., Mori T., Kaiya H., Yamazaki M., Kangawa K., Inoue K., et al. Localization of ghrelin-producing cells in the stomach of the rainbow trout (Oncorhynchus mykiss). Zool Sci 21 (2004) 757-762
27. Sánchez J., Oliver P., Palou A., and Picó C. The inhibition of gastric ghrelin production by food intake in rats is dependent on the type of macronutrient. Endocrinology 145 (2004) 5049-5055
28. Sanchez J., Oliver P., Palou A., and Pico C. The inhibition of gastric ghrelin production by food intake in rats is dependent on the type of macronutrient. Endocrinology 145 (2004) 5049-5055
29. Sanchez J., Oliver P., Pico C., and Palou A. Diurnal rhythms of leptin and ghrelin in the systemic circulation and in the gastric mucosa are related to food intake in rats. Pflugers Arch 448 (2004) 500-506
30. Small J.C., and Bloom R.S. Gut hormones and control of appetite. Trends Endocrinol Metab 15 (2004) 259-263
31. Soriano-Guillen L., Barrios V., Campos-Barros A., and Argente J. Ghrelin levels in obesity and anorexia nervosa: effect of weight reduction or recuperation. J Pediatr 144 (2004) 36-42
32. Tanaka-Shintani M., and Watanabe M. Distrubution of ghrelin-immunoreactive cells in human gastric mucosa: comparison with that of parietal cells. J Gastroenterol 40 (2005) 345-349
33. Toshinai K., Mondal M.S., Nakazato M., Date Y., Murakami N., Kojima M., et al. Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration. Biochem Biophys Res Commun 281 (2001) 1220-1225
34. Tschöp M., Smiley D.L., and Heiman M.L. Ghrelin induces adiposity in rodents. Nature 407 (2000) 908-913
35. Tschöp M., Weyer C., Tataranni P.A., Devanarayan V., Ravussin E., and Heiman M.L. Circulating ghrelin levels are decreased in human obesity. Diabetes 50 (2001) 707-709
36. Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taheri S., et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 141 (2000) 4325-4328