Vascular targeting of doxorubicin using cationic liposomes

International Journal of Pharmaceutics

Volumn 337, Issue 1-2, 2007, Pages 329-335

  Wu, Jun ^a   Lee, Alice ^a   Lu, Yanhui ^a   Lee, Robert J ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Cancer; Cationic liposomes; Doxorubicin; Vascular targeting

Indexed keywords

DIMETHYLDIOCTADECYLAMMONIUM BROMIDE; DOXORUBICIN; LIPOSOME;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER SURVIVAL; CELL LINE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG TARGETING; DRUG UPTAKE; FEMALE; LEUKEMIA CELL; LEUKEMIA L 1210; LYMPHATIC LEUKEMIA; MOUSE; MOUTH CARCINOMA; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BIOLOGICAL TRANSPORT; CATIONS; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DOXORUBICIN; DRUG COMPOUNDING; FEMALE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; INJECTIONS, INTRAVENOUS; LEUKEMIA L1210; LIPIDS; LIPOSOMES; MICE; MICE, INBRED DBA; PARTICLE SIZE; POLYETHYLENE GLYCOLS; QUATERNARY AMMONIUM COMPOUNDS; TISSUE DISTRIBUTION;

EID: 34248575531     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2007.01.003     Document Type: Article

References (22)

1. Campbell R.B., Fukumura D., Brown E.B., Mazzola L.M., Izumi Y., Jain R.K., Torchilin V.P., and Munn L.L. Cationic charge determines the distribution of liposomes between the vascular and extravascular compartments of tumors. Cancer Res. 62 (2002) 6831-6836
2. Denekamp J. Endothelial cell proliferation as a novel approach to targeting tumor therapy. Br. J. Cancer 45 (1982) 136-139
3. Denekamp J. The tumor microcirculation as a target in cancer therapy: a clearer perspective. Eur. J. Clin. Invest. 29 (1999) 733-736
4. Haran G., Cohen R., Bar L.K., and Barenholz Y. Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases. Biochim. Biophys. Acta 1151 (1993) 201-215
5. Huang S.K., Mayhew E., Gilani S., Lasic D.D., Martin F.J., and Papahadjopoulos D. Pharmacokinetics and therapeutics of sterically stabilized liposomes in mice bearing C-26 colon carcinoma. Cancer Res. 52 (1992) 6774-6781
6. Jain R.K. The next frontier of molecular medicine: delivery of therapeutics. Nat. Med. 4 (1998) 655-657
7. Kong G., Anyarambhatla G., Petros W.P., Braun R.D., Colvin O.M., Needham D., and Dewhirst M.W. Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res. 60 (2000) 6950-6957
8. Krasnici S., Werner A., Eichhorn M.E., Schmitt-Sody M., Pahernik S., Sauer B., Schulze B., Teifel M., Michaelis U., Naujoks K., and Dellian M. Effect of the surface charge of liposomes on their uptake by angiogenic tumor vessels. Int. J. Cancer 5 (2003) 561-567
9. Lee R.J., and Low P.S. Folate-mediated tumor cell targeting of liposome-entrapped doxorubincin in vitro. Biochim. Biophys. Acta 1233 (1995) 134-144
10. Litzinger D.C., Brown J.M., Wala I., Kaufman S.A., Van G.Y., Farrell C.L., and Collins D. Fate of cationic liposomes and their complex with oligonucleotide in vivo. Biochim. Biophys. Acta 1281 (1996) 139-149
11. Mahato R.I., Kawabata K., Nomyra T., Takakura Y., and Hashida M. Physicochemical and pharmacokinetic characteristics of plasmid DNA/cationic liposome complexes. J. Pharm. Sci. 84 (1995) 1267-1271
12. Mayer L.D., Tai L.C., Ko D.S., Masin D., Ginsberg R.S., Cullis P.R., and Bally M.B. Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice. Cancer Res. 49 (1989) 5922-5930
13. McLean J.W., Fox E.A., Balik P., Bolton P.B., Haskell A., Pearlman R., Thurston G., Umemoto E.Y., and McDonald D.M. Organ-specific endothelial cell uptake of cationic liposome-DNA complexes in mice. Am. J. Physiol. 273 (1997) H387-H404
14. Pan X.Q., Zheng X., Shi G.F., Wang H.Q., Ratnam M., and Lee R.J. Strategy for the treatment of acute myelogenous leukemia based on folate receptor β-targeted liposomal doxorubicin combined with receptor induction using all-trans retinoic acid. Blood 100 (2002) 594-602
15. Papahadjopoulos D., Allen T.M., Gabizon A., Mayhew E., Matthay K., Huang S.K., Lee K.D., Woodle M.C., Lasic D.D., Redemann C., and Martin F.J. Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 11460-11464
16. Parr M.J., Masin D., Cullis P.R., and Bally M.B. Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: the lack of beneficial effects by coating liposomes with poly(ethylene glycol). J. Pharmacol. Exp. Ther. 280 (1997) 1319-1327
17. Pluen A., Boucher Y., Ramaujan S., McKee T.D., Gohongi T., di Thomaso E., Brown E.B., Izumi Y., Campbell R.B., Berk D.A., and Jain R.K. Role of tumor-host interactions in interstitial diffusion of macromolecules: cranial vs. subcutaneous tumors. Proc. Natl. Sci. U.S.A. 98 (2001) 4628-4633
18. Schmitt-Sody M., Strieth S., Krasnici S., Sauer B., Schulze B., Teifel M., Michaelis U., Naujoks K., and Dellian M. Neovascular targeting therapy: paclitaxel encapsulated in cationic liposomes improves antitumoral efficacy. Clin. Cancer Res. 9 (2003) 2335-2341
19. Strieth S., Eichhorn M.E., Sauer B., Schulze B., Teifel M., Michaelis U., and Dellian M. Neovascular targeting chemotherary: encapsulation of paclitaxel in cationic liposomes impairs functional tumor microvasculaure. Int. J. Cancer 110 (2004) 117-124
20. Thurston G., McLean J.W., Rizen M., Baliuk P., Haskell A., Murphy T.J., Hanahan D., and Mcdonald D.M. Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice. J. Clin. Invest. 101 (1998) 1401-1413
21. Wu N.Z., Da D., Rudoll T.L., Needham D., Whorton A.R., and Dewhirst M.W. Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue. Cancer Res. 53 (1993) 3765-3770
22. Yuan F., Leunig M., Huang S.K., Berk D.A., Papahadjopoulos D., and Jain R.K. Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res. 54 (1994) 3352-3356