A cost-utility analysis of multivitamin and multimineral supplements in men and women aged 65 years and over

Clinical Nutrition

Volumn 26, Issue 3, 2007, Pages 364-370

  Kilonzo, Mary M ^a,b   Vale, Luke D ^a,b   Cook, Jonathan A ^b   Milne, Anne C ^b   Stephen, Audrey I ^b   Avenell, Alison ^b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Cost effectiveness; Nutrition; Oral nutritional supplementation; Quality of life; Randomised controlled trial; Vitamins and minerals

Indexed keywords

ANTIBIOTIC AGENT; MINERAL; MULTIVITAMIN; PLACEBO;

AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; COST MINIMIZATION ANALYSIS; COST UTILITY ANALYSIS; DRUG EFFICACY; ELDERLY CARE; FEMALE; GENERAL PRACTICE; HEALTH CARE COST; HEALTH CARE UTILIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; QUALITY ADJUSTED LIFE YEAR; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SENSITIVITY ANALYSIS; STATISTICAL SIGNIFICANCE; UNITED KINGDOM; VITAMIN SUPPLEMENTATION;

AGED; AGED, 80 AND OVER; AGING; COST-BENEFIT ANALYSIS; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFECTION; INFECTION CONTROL; MALE; MINERALS; NUTRITION PHYSIOLOGY; NUTRITIONAL REQUIREMENTS; QUALITY-ADJUSTED LIFE YEARS; VITAMINS;

EID: 34248563189     PISSN: 02615614     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clnu.2006.11.002     Document Type: Article

References (20)

1. Lesourd B. Immune response during disease and recovery in the elderly. Proc Nutr Soc 58 (1999) 85-98
2. Glezen W.P., Greenberg S.B., Atmar R.L., Piedra P.A., and Couch R.B. Impact of respiratory virus infections on persons with chronic underlying conditions. J Am Med Assoc 283 (2000) 499-505
3. Scrimshaw N.S., and SanGiovanni J.P. Synergism of nutrition, infection, and immunity: an overview. Am J Clin Nutr 66 (1997) 464S-477S
4. El-Kadiki A., and Sutton A.J. Role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomized controlled trials. Br Med J 330 (2005) 871-874
5. Sutton A, El-Kadiki A. Assessing concerns regarding the validity of three trials included in role of multivitamins and mineral supplements in preventing infections in elderly people: systematic review and meta-analysis of randomised controlled trials. 〈http://bmj.bmjjournals.com/cgi/content/full/bmj.38399.495648.8F/DC2〉 [accessed 31 August 2006].
6. Chavance M., Herbeth B., Lemoine A., and Zhu B.P. Does multivitamin supplementation prevent infections in healthy elderly subjects? A controlled trial. Int J Vitam Nutr Res 63 (1993) 11-16
7. Graat J.M., Schouten E.G., and Kok F.J. Effect of daily vitamin E and multivitamin-mineral supplementation on acute respiratory infections in elderly persons. A randomised controlled trial. J Am Med Assoc 288 (2002) 715-721
8. Barringer T.A., Kirk J.K., Santaniello A.C., Foley K.L., and Michielutte R. Effect of a multivitamin and mineral supplement on infection and quality of life. A randomised, double-blind, placebo-controlled trial. Ann Intern Med 138 (2003) 365-371
9. Writing Group of the MAVIS trial. Effect of multivitamin and multimineral supplements on morbidity from infections in older people (MAVIS trial): pragmatic, randomized, double-blind, placebo controlled trial. Br Med J 331 (2005) 320-324
10. Netten A, Curtis L. Unit costs of health and social care. Personal Social Services Research Unit, Canterbury: University of Kent at Canterbury; 2002.
11. Amendment 92 to the Statement of Dental Remuneration. UK Department of Health. Available from: 〈http://www.dh.gov.uk/assetRoot/04/08/11/28/04081128.pdf〉 [accessed May 2004].
12. British Medical Association, Royal Pharmaceutical Society of Great Britain. British National Formulary (BNF) number 49. London: British Medical Association and Royal Pharmaceutical Society of Great Britain; 2004.
13. Information and Statistics Division. Scottish health service costs 2003. 〈http://www.isdscotland.org/isd/files/Costs〉 [accessed May 2004].
14. Kind P, Hardman G, Macran S. UK Population norms for EQ-5D. Centre for Health Economics Discussion paper 172, York: University of York; 1999.
15. National Institute for Health and Clinical Excellence (NICE). Guide to the methods of technology appraisal. Available from the NICE website: 〈http://www.nice.org.uk/page.aspx?o=209714〉, 2004.
16. Briggs A.H., and Gray A.M. Handling uncertainty when performing economic evaluation of healthcare interventions. Health Technol Assess 3 2 (1999)
17. Detsky A.S. Guidelines for economic analysis of pharmaceutical products: a draft document for Ontario and Canada. Pharmacoeconomics 3 (1993) 354-361
18. National diet and nutrition survey: people aged 65 years and over. London: Stationery Office; 1998.
19. Girodon F., Lombard M., Galan P., et al. Effect of micronutrient supplementation on infection in institutionalized elderly subjects: a controlled trial. Ann Nutr Metab 41 (1997) 98-107
20. Girodon F., Galan P., Monget A.-L., et al. Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients. A randomized controlled trial. Arch Intern Med 159 (1999) 748-754