Progesterone and progesterone receptor modulator in uterine leiomyoma growth

Gynecological Endocrinology

Volumn 23, Issue 4, 2007, Pages 186-187

  Maruo, Takeshi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

17ALPHA ACETOXY 11BETA (4 DIMETHYLAMINOPHENYL) 19 NORPREGNA 4,9 DIENE 3,20 DIONE; EPIDERMAL GROWTH FACTOR; LEVONORGESTREL; PROGESTERONE; PROGESTERONE RECEPTOR; SOMATOMEDIN BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ANGIOGENESIS; APOPTOSIS; CELL STIMULATION; CELL TYPE; COMPETITIVE INHIBITION; DOWN REGULATION; DRUG RECEPTOR BINDING; EDITORIAL; GROWTH REGULATION; HORMONE RECEPTOR INTERACTION; HUMAN; PRIORITY JOURNAL; PROGESTERONE BLOOD LEVEL; PROGESTERONE RELEASE; PROTEIN EXPRESSION; TUMOR GROWTH; UPREGULATION; UTERUS MYOMA;

CONTRACEPTIVE AGENTS, FEMALE; FEMALE; HUMANS; INTRAUTERINE DEVICES; LEIOMYOMA; LEVONORGESTREL; NORPREGNADIENES; RECEPTORS, PROGESTERONE;

EID: 34248551359     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.1080/09513590701350416     Document Type: Editorial

References (13)

1. Maruo T, Matsuo H, Gao Z, Spitz IM, Johansson E. Effects of progesterone on uterine leiomyoma growth and apoptosis. Steroids 2000;65:585-592.
2. Maruo T, Laoag-Fernandez JB, Pakarinen P, Spitz IM, Johansson E. Effects of levonorgestrel-releasing intrauterine system on the endometrium and the relevance to the management of menorrhagia caused by uterine myoma and adenomyosis. In: Maruo T, Barlow D, Mardon H, Kennedy S, editors. Cell and molecular biology of endometrium in health and disease. Osaka: Soeisha; 2002. pp 193-207.
3. Maruo T, Laoag-Fernandez JB, Spitz IM, Johansson E. Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium. Hum Reprod 2001;16:2103-2108.
4. Maruo T. Endometrial effects of levonorgestrel intrauterine delivery. Gynecol Forum 2006;11:27-30.
5. Gao Z, Matsuo H, Nakago S, Maruo T. Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 protein expression in human uterine leiomyoma cells. J Clin Endocrinol Metab 2001;86:5593-5599.
6. Shimomura Y, Matsuo H, Samoto T, Maruo T. Upregulation by progesterone of proliferating cell number antigen and epidermal growth factor expression in human uterine leiomyoma. J Clin Endocrinol Metab 1998;83:2192-2198.
7. Matsuo H, Maruo T, Samoto T. Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone. J Clin Endocrinol Metab 1997;82:293-299.
8. Kurachi O, Matsuo H, Maruo T. Tumor necrosis factor-a expression in human uterine leiomyoma and its downregulation by progesterone. J Clin Endocrinol Metab 2001;86:2275-2280.
9. Yamada T, Nakago S, Matsuo H, Maruo T. Progesterone down-regulates insulin-like growth factor-I expression in cultured human uterine leiomyoma cells. Hum Reprod 2004;19:1-7.
10. Maruo T, Ohara N, Wang J, Matsuo H. Sex steroidal regulation of uterine leiomyoma growth and apoptosis. Hum Reprod Update 2004;10:207-220.
11. Maruo T, Matsuo H, Yamada T, Kurachi O, Gao Z, Nakago S, Yamada T, Chen W, Wang J. Effects of progesterone on growth factor expression in human uterine leiomyoma. Steroids 2003;68:817-824.
12. Xu Q, Ohara N, Sitruk-Ware R, Johansson EDB, Maruo T. Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and (adenosine 5′-diphosphateribose) polymerase expression in cultured human uterine leiomyoma cells. J Clin Endocrinol Metab 2005;90:953-961.
13. Xu Q, Ohara N, Maruo T, Liu J, Sasaki H, Morikawa A, Sitruk-Ware R, Johansson ED, Maruo T. Progesterone receptor modulator CDB2914 down-regulates VEGF, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells. Hum Reprod 2006;21:2408-2416.