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1
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0036891417
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Comparison of the efficacy, safety and predictive value of HIV genotyping using distinct ritonavirboosted protease inhibitors
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Barreiro P, Camino N, de Mendoza C, Valer L, Nunez M, Martin-Carbonero L, et al. Comparison of the efficacy, safety and predictive value of HIV genotyping using distinct ritonavirboosted protease inhibitors. Int J Antimicrob Agents 2002; 20:438-443.
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(2002)
Int J Antimicrob Agents
, vol.20
, pp. 438-443
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Barreiro, P.1
Camino, N.2
de Mendoza, C.3
Valer, L.4
Nunez, M.5
Martin-Carbonero, L.6
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2
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33750630109
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Update of the drug resistance mutations in HIV-1: Fall 2006
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Johnson VA, Brun-Vezinet F, Clotet B, Kuritzkes DR, Pillay D, Schapiro JM, et al. Update of the drug resistance mutations in HIV-1: fall 2006. Top HIV Med 2006; 14:125-130.
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(2006)
Top HIV Med
, vol.14
, pp. 125-130
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Johnson, V.A.1
Brun-Vezinet, F.2
Clotet, B.3
Kuritzkes, D.R.4
Pillay, D.5
Schapiro, J.M.6
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3
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19544386471
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TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
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De Meyer S, Azijn H, Surleraux D, Jochmans D, Tahri A, Pauwels R, et al. TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates. Antimicrob Agents Chemother 2005; 49:2314-2321.
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(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 2314-2321
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De Meyer, S.1
Azijn, H.2
Surleraux, D.3
Jochmans, D.4
Tahri, A.5
Pauwels, R.6
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4
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33746255655
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Successful rescue therapy with darunabir (TMC114) in HIV-infected patients who have failed several ritonavir-boosted protease inhibitors
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Poveda E, Blanco F, Garcia-Gasco P, Alcolea A, Briz V, Soriano V. Successful rescue therapy with darunabir (TMC114) in HIV-infected patients who have failed several ritonavir-boosted protease inhibitors. AIDS 2006; 20:1558-1560.
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(2006)
AIDS
, vol.20
, pp. 1558-1560
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Poveda, E.1
Blanco, F.2
Garcia-Gasco, P.3
Alcolea, A.4
Briz, V.5
Soriano, V.6
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5
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33746868528
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TMC114/r outperforms investigator-selected PI(s) in 3-class-experienced patients: Week 24 primary efficacy analysis of Power 1 (TMC114-C213)
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Rio de Janeiro, Brazil, 24-27 July, Abstract WeOaLB0102
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Katlama C, Carvalho MT, Cooper D, De Backer K, Lefebvre E, Pedro R, et al. TMC114/r outperforms investigator-selected PI(s) in 3-class-experienced patients: week 24 primary efficacy analysis of Power 1 (TMC114-C213). In: 3rd IAS Conference on HIV Pathogenesis and Treatment. Rio de Janeiro, Brazil, 24-27 July 2005 [Abstract WeOaLB0102].
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(2005)
3rd IAS Conference on HIV Pathogenesis and Treatment
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Katlama, C.1
Carvalho, M.T.2
Cooper, D.3
De Backer, K.4
Lefebvre, E.5
Pedro, R.6
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6
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33750314199
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TMC114/r superior of care in 3-class-experienced patients: 24-wks primary analysis of the Power 2 study (C202)
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Washington, USA, 16-19 December, Abstract H-413
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Wilkin T, Haubrich R, Steinhart C, Becker S, Conant M, Vangeneugden T, et al. TMC114/r superior of care in 3-class-experienced patients: 24-wks primary analysis of the Power 2 study (C202). In: 45th Interscience Conference on Antimicrobial Agents and Chemotherapy. Washington, USA, 16-19 December 2005 [Abstract H-413].
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(2005)
45th Interscience Conference on Antimicrobial Agents and Chemotherapy
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Wilkin, T.1
Haubrich, R.2
Steinhart, C.3
Becker, S.4
Conant, M.5
Vangeneugden, T.6
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7
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34248584422
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Effect of baseline susceptibility and on-treatment mutations TMC114 and control PI efficacy
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Denver, CO, USA, 5-8 February, Abstract 157
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De Meyer S, Hill A, De Baere I, Rimsky L, Azijn H, VanBaelen B, et al. Effect of baseline susceptibility and on-treatment mutations TMC114 and control PI efficacy. In: 13th Conference on Retroviruses and Opportunistic Infections. Denver, CO, USA, 5-8 February 2006 [Abstract 157].
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(2006)
13th Conference on Retroviruses and Opportunistic Infections
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De Meyer, S.1
Hill, A.2
De Baere, I.3
Rimsky, L.4
Azijn, H.5
VanBaelen, B.6
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8
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34347373461
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Clinical pharmacology of TMC114 - a new HIV protease inhibitor
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Toronto, Canada, 13-18 August, Abstract TUPE0083
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Sekar V, Spinosa-Guzman S, Lefebvre E, Hoetelmans R. Clinical pharmacology of TMC114 - a new HIV protease inhibitor. In: XVIth International AIDS Conference. Toronto, Canada, 13-18 August 2006 [Abstract TUPE0083].
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(2006)
XVIth International AIDS Conference
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Sekar, V.1
Spinosa-Guzman, S.2
Lefebvre, E.3
Hoetelmans, R.4
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9
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6344231715
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Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor
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King NM, Prabu-Jeyabalan M, Nalivaika EA, Wigerinck P, de Bethune MP, Schiffer CA. Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor. J Virol 2004; 78: 12012-12021.
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(2004)
J Virol
, vol.78
, pp. 12012-12021
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King, N.M.1
Prabu-Jeyabalan, M.2
Nalivaika, E.A.3
Wigerinck, P.4
de Bethune, M.P.5
Schiffer, C.A.6
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10
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34248595520
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HIV-1 susceptibility to TMC114 among routine clinical samples with different levels of protease inhibitor susceptibility using linear regression model-based fold change predictions
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San Francisco, USA, 27-30 September, Abstract 402
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Picchio G, Staes M, Van Craenenbroeck E, Vermeiren H, Bacheler L, De Bethune MP, et al. HIV-1 susceptibility to TMC114 among routine clinical samples with different levels of protease inhibitor susceptibility using linear regression model-based fold change predictions. In: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, USA, 27-30 September 2006 [Abstract 402].
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(2006)
46th Interscience Conference on Antimicrobial Agents and Chemotherapy
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Picchio, G.1
Staes, M.2
Van Craenenbroeck, E.3
Vermeiren, H.4
Bacheler, L.5
De Bethune, M.P.6
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11
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34248584421
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Impact of use of TPV, LPV, and(f)APV at screening on TMC114/r virologic response in treatment-experienced patients in POWER 1, 2 and 3
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San Francisco, USA, 27-30 September, Abstract H-1387
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Lefebvre E, de Bethune MP, De Meyer S, Vangeneugden T, De Pauw M, Cefalone M, et al. Impact of use of TPV, LPV, and(f)APV at screening on TMC114/r virologic response in treatment-experienced patients in POWER 1, 2 and 3. In: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, USA, 27-30 September 2006 [Abstract H-1387].
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(2006)
46th Interscience Conference on Antimicrobial Agents and Chemotherapy
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Lefebvre, E.1
de Bethune, M.P.2
De Meyer, S.3
Vangeneugden, T.4
De Pauw, M.5
Cefalone, M.6
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12
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0036174439
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Emergence of resistance to protease inhibitor amprenavir in human patients: Selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors
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Maguire M, Shortino D, Klein A, Harris W, Manohitharajah V, Tisdale M, et al. Emergence of resistance to protease inhibitor amprenavir in human patients: selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors. Antimicrob Agents Chemother 2002; 46:731-738.
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(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 731-738
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Maguire, M.1
Shortino, D.2
Klein, A.3
Harris, W.4
Manohitharajah, V.5
Tisdale, M.6
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