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Volumn 21, Issue 9, 2007, Pages 1210-1213

Key amprenavir resistance mutations counteract dramatic efficacy of darunavir in highly experienced patients

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; AMPRENAVIR PHOSPHATE; DARUNAVIR; EFAVIRENZ; EMTRICITABINE; ENFUVIRTIDE; LAMIVUDINE; LOPINAVIR; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; TENOFOVIR; TIPRANAVIR; ZIDOVUDINE;

EID: 34248549145     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32810fd744     Document Type: Article
Times cited : (23)

References (12)
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  • 3
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    • TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates
    • De Meyer S, Azijn H, Surleraux D, Jochmans D, Tahri A, Pauwels R, et al. TMC114, a novel human immunodeficiency virus type 1 protease inhibitor active against protease inhibitor-resistant viruses, including a broad range of clinical isolates. Antimicrob Agents Chemother 2005; 49:2314-2321.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 2314-2321
    • De Meyer, S.1    Azijn, H.2    Surleraux, D.3    Jochmans, D.4    Tahri, A.5    Pauwels, R.6
  • 4
    • 33746255655 scopus 로고    scopus 로고
    • Successful rescue therapy with darunabir (TMC114) in HIV-infected patients who have failed several ritonavir-boosted protease inhibitors
    • Poveda E, Blanco F, Garcia-Gasco P, Alcolea A, Briz V, Soriano V. Successful rescue therapy with darunabir (TMC114) in HIV-infected patients who have failed several ritonavir-boosted protease inhibitors. AIDS 2006; 20:1558-1560.
    • (2006) AIDS , vol.20 , pp. 1558-1560
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  • 5
    • 33746868528 scopus 로고    scopus 로고
    • TMC114/r outperforms investigator-selected PI(s) in 3-class-experienced patients: Week 24 primary efficacy analysis of Power 1 (TMC114-C213)
    • Rio de Janeiro, Brazil, 24-27 July, Abstract WeOaLB0102
    • Katlama C, Carvalho MT, Cooper D, De Backer K, Lefebvre E, Pedro R, et al. TMC114/r outperforms investigator-selected PI(s) in 3-class-experienced patients: week 24 primary efficacy analysis of Power 1 (TMC114-C213). In: 3rd IAS Conference on HIV Pathogenesis and Treatment. Rio de Janeiro, Brazil, 24-27 July 2005 [Abstract WeOaLB0102].
    • (2005) 3rd IAS Conference on HIV Pathogenesis and Treatment
    • Katlama, C.1    Carvalho, M.T.2    Cooper, D.3    De Backer, K.4    Lefebvre, E.5    Pedro, R.6
  • 9
    • 6344231715 scopus 로고    scopus 로고
    • Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor
    • King NM, Prabu-Jeyabalan M, Nalivaika EA, Wigerinck P, de Bethune MP, Schiffer CA. Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor. J Virol 2004; 78: 12012-12021.
    • (2004) J Virol , vol.78 , pp. 12012-12021
    • King, N.M.1    Prabu-Jeyabalan, M.2    Nalivaika, E.A.3    Wigerinck, P.4    de Bethune, M.P.5    Schiffer, C.A.6
  • 10
    • 34248595520 scopus 로고    scopus 로고
    • HIV-1 susceptibility to TMC114 among routine clinical samples with different levels of protease inhibitor susceptibility using linear regression model-based fold change predictions
    • San Francisco, USA, 27-30 September, Abstract 402
    • Picchio G, Staes M, Van Craenenbroeck E, Vermeiren H, Bacheler L, De Bethune MP, et al. HIV-1 susceptibility to TMC114 among routine clinical samples with different levels of protease inhibitor susceptibility using linear regression model-based fold change predictions. In: 46th Interscience Conference on Antimicrobial Agents and Chemotherapy. San Francisco, USA, 27-30 September 2006 [Abstract 402].
    • (2006) 46th Interscience Conference on Antimicrobial Agents and Chemotherapy
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    • Emergence of resistance to protease inhibitor amprenavir in human patients: Selection of four alternative viral protease genotypes and influence of viral susceptibility to coadministered reverse transcriptase nucleoside inhibitors
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.