Clues from alopecia areata on the role of neuropeptides in the initiation of autoimmunity

Journal of Investigative Dermatology

Volumn 127, Issue 6, 2007, Pages 1289-1291

  Kalish, Richard S ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NEUROPEPTIDE; SUBSTANCE P;

ALOPECIA AREATA; AUTOIMMUNE DISEASE; AUTOIMMUNITY; BRAIN; CD8+ T LYMPHOCYTE; IMMUNOLOGICAL TOLERANCE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW;

EID: 34248546738     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700655     Document Type: Note

References (10)

1. Botchkarev VA, Yaar M, Peters EM, Raychaudhuri SP, Botchkareva NV, Marconi A et al. (2006) Neurotrophins in skin biology and pathology. J Invest Dermatol 126:1719-27
2. Ito T, Ito N, Bettermann A, Tokura Y, Takigawa M, Paus R (2004) Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model. Am J Pathol 164:623-34
3. Gilhar A, Assy B, Yossi Kam, Kalish RS (2005) Alopecia areata induced in C3H/HeJ mice by interferon-gamma: evidence for loss of immune privilege. J Invest Dermatol 124:288-9
4. Gilhar A, Kalish RS (2006) Alopecia areata: a tissue specific autoimmune disease of the hair follicle. Autoimmun Rev 5:64-9
5. Gilhar A, Ullmann Y, Berkutzki T, Assy B, Kalish RS (1998) Alopecia areata transferred to human scalp explants on SCID mice with T-lymphocyte injections. J Clin Invest 101:62-7
6. McElwee KJ, Boggess D, King LE Jr., Sundberg JP (1998) Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts. J Invest Dermatol 111:797-803
7. Meyronet D, Jaber K, Gentil-Perret A, Cambazard F, Misery L (2003) Decreased CGRP staining in alopecia areata. Br J Dermatol 149:422-4
8. Paus R, Slominski A, Czarnetzki BM (1993) Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? Yale J Biol Med 66:541-54
9. Rossi R, Del Bianco E, Isolani D, Baccari MC, Cappugi P (1997) Possible involvement of neuropeptidergic sensory nerves in alopecia areata. Neuroreport 8:1135-8
10. Siebenhaar F, Sharov AA, Peters EMJ, Sharova TY, Syska W, Mardaryev AN et al. (2007) Substance P as an immunomodulatory neuropeptide in a mouse model for autoimmune hair loss (alopecia areata). J Invest Dermatol 127:1489-97