CSF flow cytometry greatly improves diagnostic accuracy in CNS hematologic malignancies

Neurology

Volumn 68, Issue 20, 2007, Pages 1674-1679

  Bromberg, J E C ^a   Breems, D A ^a   Kraan, J ^a   Bikker, G ^a   Van Der Holt, B ^a   Smitt, P Sillevis ^a   Van Den Bent, M J ^a   Van't Veer, M ^a   Gratama, J W ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER CELL; CANCER DIAGNOSIS; CANCER SURVIVAL; CELL STRUCTURE; CENTRAL NERVOUS SYSTEM TUMOR; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE FREE SURVIVAL; FLOW CYTOMETRY; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; INTERMETHOD COMPARISON; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; PLEOCYTOSIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN CONTENT; SAMPLE; TUMOR LOCALIZATION;

CELL COUNT; CEREBROSPINAL FLUID; CEREBROSPINAL FLUID PROTEINS; CYTOLOGICAL TECHNIQUES; DISEASE-FREE SURVIVAL; FALSE POSITIVE REACTIONS; FLOW CYTOMETRY; FOLLOW-UP STUDIES; HEMATOLOGIC NEOPLASMS; HUMANS; LEUKEMIA, MYELOID; LEUKEMIC INFILTRATION; LEUKOCYTOSIS; LYMPHOMA, B-CELL; MENINGES; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RETROSPECTIVE STUDIES;

EID: 34248531956     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/01.wnl.0000261909.28915.83     Document Type: Article

References (16)

1. Glass JP, Melamed M, Chernik NL, Posner JB. Malignant cells in cerebrospinal fluid (CSF): the meaning of a positive CSF cytology. Neurology 1979;29:1369-1375.
2. Freilich RJ, Krol G, DeAngelis LM. Neuroimaging and cerebrospinal fluid cytology in the diagnosis of leptomeningeal metastasis. Ann Neurol 1995;38:51-57.
3. Kaplan JG, DeSouza TG, Farkash A, et al. Leptomeningeal metastases: comparison of clinical features and laboratory data of solid tumors, lymphomas and leukemias. J Neuro-oncol 1990;9:225-229.
4. Wasserstrom WR, Glass JP, Posner JB. Diagnosis and treatment of leptomeningeal metastases from solid tumors: experience with 90 patients. Cancer 1982;49:759-772.
5. Clinical and Laboratory Standards Institute. Clinical flow cytometric analysis of neoplastic hematolymphoid cells; approved guideline, 2nd edition. CLSI document H43-A2 [ISBN 1-56238-000-0]. Wayne, PA: CLSI, 2006.
6. Stetler-Stevenson M, Braylan RC. Flow cytometric analysis of lymphomas and lymphoproliferative disorders. Semin Hematol 2001;38:111-123.
7. Hegde U, Filie A, Little RF, et al. High incidence of occult leptomeningeal disease detected by flow cytometry in newly diagnosed aggressive B-cell lymphomas at risk for central nervous system involvement: the role of flow cytometry versus cytology. Blood 2005;105:496-502.
8. Nowakowski GS, Call TG, Morice WG, Kurtin PJ, Cook RJ, Zent CS. Clinical significance of monoclonal B cells in cerebrospinal fluid. Cytometry B Clin Cytometry 2005;63:23-27.
9. Finn WG, Peterson LC, James C, Goolsby CL. Enhanced detection of malignant lymphoma in cerebrospinal fluid by multiparameter flow cytometry. Am J Clin Pathol 1998;110:341-346.
10. French CA, Dorfman DM, Shaheen G, Cibas ES. Diagnosing lymphoproliferative disorders involving the cerebrospinal fluid: increased sensitivity using flow cytometric analysis. Diagn Cytopathol 2000;23:369-374.
11. Subira D, Castanon S, Roman A, et al. Flow cytometry and the study of central nervous disease in patients with acute leukaemia. Br J Haematol 2001;112:381-384.
12. Peter A. Cytological changes in the cerebrospinal fluid following intrathecal methotrexate treatment. I. Observations in adult meningeal leukemia. Confin Neurol 1974;36:186-196.
13. Kraan J, Gratama JW, Keeney M, D'Hautcourt JL. Setting up and calibration of a flow cytometer for multicolor immunophenotyping. J Biol Regul Homeost Agents 2003;17:223-233.
14. Roma AA, Garcia A, Avagnina A, Rescia C, Elsner B. Lymphoid and myeloid neoplasms involving cerebrospinal fluid: comparison of morphologic examination and immunophenotyping by flow cytometry. Diagn Cytopathol 2002;27:271-275.
15. Subira D, Gorgolas M, Castanon S, et al. Advantages of flow cytometry immunophenotyping for the diagnosis of central nervous system non-Hodgkin's lymphoma in AIDS patients. HIV Med 2005;6:21-26.
16. Schistine M, Filie AC, Wilson W, Stetler-Stevenson M, Abati A. Detection of malignant hematopoietic cells in cerebral spinal fluid previously diagnosed as atypical or suspicious. Cancer (Cancer Cytopathol) 2006;108:157-162.