Empirical evaluation of the generalizability of the sample from the multimodal treatment study for ADHD

Administration and Policy in Mental Health and Mental Health Services Research

Volumn 34, Issue 3, 2007, Pages 221-232

  Stevens, Jack ^a   Kelleher, Kelly ^a   Greenhouse, Joel ^b   Chen, Guanmin ^c   Xiang, Huiyun ^a   Kaizar, Eloise ^b   Jensen, Peter S ^d   Arnold, L Eugene ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b CARNEGIE MELLON UNIVERSITY   (United States)

^c WUHAN UNIVERSITY   (China)

^d Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

ADHD; External validity; Generalizability

Indexed keywords

ARTICLE; ATTENTION DEFICIT DISORDER; CLINICAL FEATURE; CLINICAL RESEARCH; DEMOGRAPHY; EVALUATION; EXTERNAL VALIDITY; HEALTH SURVEY; MEDICAL EXPERT; POPULATION RECOVERY; PRIORITY JOURNAL; VALIDATION STUDY;

ADOLESCENT; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; CANADA; CHILD; COMBINED MODALITY THERAPY; EMPIRICAL RESEARCH; FEMALE; HEALTH SURVEYS; HUMANS; MALE; UNITED STATES;

EID: 34248373844     PISSN: 0894587X     EISSN: 15733289     Source Type: Journal    
DOI: 10.1007/s10488-006-0097-4     Document Type: Article

References (31)

1. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: American Psychiatric Association.
2. Arnold, L. E., Abikoff, H. B., Cantwell, D. P., Conners, C. K., Elliott, G., Greenhill, L. L., Hechtman, L., Hinshaw, S. P., Hoza, B., Jensen, P. S., Kraemer, H. C., March, J. S., Newcorn, J. H., Pelham, W. E., Richters, J. E., Schiller, E., Severe, J. B., Swanson, J. M., Vereen, D., & Wells, K. C. (1997). National Institute of Mental Health Collaborative Multimodal Treatment Study of Children with ADHD (the MTA). Design challenges and choices. Archives of General Psychiatry, 54, 865-870.
3. Arnold, L. E., Elliott, M., Sachs, L., Bird, H., Kraemer, H. C., Wells, K. C., Abikoff, H. B., Comarda, A., Conners, C. K., Elliott, G. R., Greenhill, L. L., Hechtman, L., Hinshaw, S. P., Hoza, B., Jensen, P. J., March, J. S., Newcorn, J., Pelham, W. E., Severe, J. B., Swanson, J. M., Vitiello, B., & Wigal, T. (2003). Effects of ethnicity on treatment attendance, stimulant response/dose, and 14-month outcome in ADHD. Journal of Consulting and Clinical Psychology, 71, 713-727.
4. Barkley, R. A. (2000). Commentary on the multimodal treatment study of children with ADHD. Journal of Abnormal Child Psychology, 28, 595-599.
5. Beck, A. T., Ward, C. H., Mendelson, M., Mock, J. E., & Erbaugh, J. K. (1961). An inventory for measuring depression. Archives of General Psychiatry, 4, 561-571.
6. Bird, H. R., Gould, M. S., & Staghezza, B. M. (1993). Patterns of diagnostic comorbidity in a community sample of children aged 9 through 16 years. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 361-368.
7. Conners, C. K., Epstein, J. N., March, J. S., Angold, A., Wells, K. C., Klaric, J., Swanson, J. M., Arnold, L. E., Abikoff, H. B., Elliott, G. R., Greenhill, L. L., Hechtman, L., Hinshaw, S. P., Hoza, B., Jensen, P. S., Kraemer, H. C., Newcorn, J. H., Pelham, W. E., Severe, J. B., Vitiello, B., & Wigal, T. (2001). Multimodal treatment of ADHD in the MTA: An alternative outcome analysis. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 159-167.
8. Dunn, L. M., Dunn, L. M. (1981). Peabody picture vocabulary test-revised. Circle Pines, MN: American Guidance Service.
9. Farmer, E. M., Stangl, D. K., Burns, B. J., Costello, E. J., & Angold, A. (1999). Use, persistence, and intensity: Patterns of care for children's mental health across one year. Community Mental Health Journal, 35, 31-46.
10. Fisher, P., Wicks, J., Shaffer, D., Piacentini, J., & Lapkin, J. (1992). NIMH diagnostic interview schedule for children, version 2.3, user's manual. New York: New York State Psychiatric Institute.
11. General Accounting Office. (1992). Cross design synthesis: A new strategy for medical effectiveness research. Washington, DC: GAO.
12. Greenhill, L. L., Swanson, J. M., Vitiello, B., Davies, M., Clevenger, W., Wu, M., Arnold, L. E., Abikoff, H. B., Bukstein, O. G., Conners, C. K., Elliott, G. R., Hechtman, L., Hinshaw, S. P., Hoza, B., Jensen, P. S., Kraemer, H. C., March, J. S., Newcorn, J. H., Severe, J. B., Wells, K., & Wigal, T. (2001). Impairment and deportment responses to different methylphenidate doses in children with ADHD: The MTA titration trial. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 180-187.
13. Jensen, P. S., Hinshaw, S. P., Kraemer, H. C., Lenora, N., Newcorn, J. H., Abikoff, H. B., March, J. S., Arnold, L. E., Cantwell, D. P., Conners, C. K., Elliott, G. R., Greenhill, L. L., Hechtman, L., Hoza, B., Pelham, W. E., Severe, J. B., Swanson, J. M., Wells, K. C., Wigal, T., & Vitiello, B. (2001). ADHD comorbidity findings from the MTA study: Comparing comorbid subgroups. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 147-158.
14. Korn, E. L., & Graubard, B. I. (1999). Analysis of health surveys. New York: Wiley Press.
15. Lahey, B. B., Flagg, E. W., Bird, H. R., Schwab-Stone, M. E., Canino, G., Dulcan, M. K., Leaf, P. J., Davies, M., Brogan, D., Bourdon, K., Horwitz, S. M., Rubio-Stipec, M., Freeman, D. H., Lichtman, J. H., Shaffer, D., Goodman, S. H., Narrow, W. E., Weissman, M. M., Kandel, D. B., Jensen, P. S., Richters, J. E., & Regier, D. A. (1996). The NIMH Methods for the Epidemiology of Child and Adolescent Mental Disorders (MECA) study: Background and methodology. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 855-864.
16. Leaf, P., Alegria, M., Cohen, P., Goodman, S., Horwitz, S. M., Hoven, C. W., Narrow, W. E., Vaden-Kiernan, M., & Regier, D. A. (1996). Mental health service use in the community and schools: Results from the four-community MECA study. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 889-897.
17. MTA Cooperative Group. (1999a). A 14-month randomized clinical trial of treatment strategies for attention-deficit/hyperactivity disorder. Multimodal Treatment Study of Children with ADHD. Archives of General Psychiatry, 56, 1073-1086.
18. MTA Cooperative Group. (1999b). Moderators and mediators of treatment response for children with attention-deficit/hyperactivity disorder: The Multimodal Treatment Study of children with Attention-deficit/hyperactivity disorder. Archives of General Psychiatry, 56, 1088-1096.
19. Owens, E. B., Hinshaw, S. P., Kraemer, H. C., Arnold, L. E., Abikoff, H. B., Cantwell, D. P., Conners, C. K., Elliott, G., Greenhill, L. L., Hechtman, L., Hoza, B., Jensen, P. S., March, J. S., Newcorn, J. H., Pelham, W. E., Severe, J. B., Swanson, J. M., Vitiello, B., Wells, K. C., & Wigal, T. (2003). Which treatment for whom for ADHD? Moderators of treatment response in the MTA. Journal of Consulting and Clinical Psychiatry, 71, 540-552.
20. Rieppi, R., Greenhill, L. L., Ford, R. E., Chuang, S., Wu, M., Davies, M., Abikoff, H. B., Arnold, L. E., Conners, C. K., Elliott, G. R., Hechtman, L., Hinshaw, S. P., Hoza, B., Jensen, P. S., Kraemer, H. C., March, J. S., Newcorn, J. H., Pelham, W. E., Severe, J. B., Swanson, J. M., Vitiello, B., Wells, K. C., & Wigal, T. (2002). Socioeconomic status as a moderator of ADHD treatment outcomes. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 269-277.
21. Rothwell, P. (2005). External validity of randomised controlled trials: To whom do the results of this trial apply? Lancet, 365, 82-93.
22. Shaffer, D., Fisher, P., Dulcan, M. K., Davies, M., Piacentini, J., Schwab-Stone, M. E., Lahey, B. B., Bourdon, K., Jensen, P. S., Bird, H. R., Canino, G., & Regier, D. A. (1996). The NIMH Diagnostic Interview Schedule for Children Version 2.3 (DISC-2.3): Description, acceptability, prevalence rates, and performance in the MECA Study. Methods for the Epidemiology of Child and Adolescent Mental Disorders Study. Journal of the American Academy of Child and Adolescent Psychiatry, 35, 865-877.
23. Persons, J. B., & Silberschatz, G. (1998). Are results of randomized controlled trials useful to psychotherapists? Journal of Consulting and Clinical Psychology, 66, 126-135.
24. SPSS Inc. (2003). SPSS base 12.0 application guide. Chicago, IL: Author.
25. Stevens, J., Harman, J. S., & Kelleher, K. J. (2005). Race/ethnicity and insurance status as factors associated with ADHD treatment patterns. Journal of Child and Adolescent Psychopharmacology, 15, 88-96.
26. Stirman, S. W., DeRubeis, R. J., Crits-Christoph, P., & Brody, P. E. (2003). Are samples in randomized controlled trials of psychotherapy representative of community outpatients? A new methodology and initial findings. Journal of Consulting and Clinical Psychology, 71, 963-972.
27. Swanson, J. M., Kraemer, H. C., Hinshaw, S. P., Arnold, L. E., Conners, C. K., Abikoff, H. B., Clevenger, W., Davies, M., Elliott, G. R., Greenhill, L. L., Hechtman, L., Hoza, B., Jensen, P. S., March, J. S., Newcorn, J. H., Owens, E. B., Pelham, W. E., Schiller, E., Severe, J. B., Simpson, S., Vitiello, B., Wells, K., Wigal, T., & Wu, M. (2001). Clinical relevance of the primary findings of the MTA: Success rates based on severity of ADHD and ODD symptoms at the end of treatment. Journal of the American Academy of Child and Adolescent Psychiatry, 40, 168-179.
28. Wechsler, D. (1991). Wechsler intelligence Scale for Children - Third Edition San Antonio. TX: Psychological Corporation.
29. Westen, D. I. (2006). Patients and treatments in clinical trials are not adequately representative of clinical practice. In J. C. Norcross, L. E. Beutler, & R. F. Levant (Eds.), Evidence-based practices in mental health: Debate and dialogue on the fundamental questions. Washington, DC: American Psychological Association.
30. Zimmerman, M., Chelminski, I., & Posternak, M. A. (2005). Generalizability of antidepressant efficacy trials: Differences between depressed psychiatric outpatients who would versus would not qualify for an efficacy trial. American Journal of Psychiatry, 162, 1370-1372.
31. Zimmerman, M., Mattia, J. I., & Posternak, M. A. (2002). Are subjects in pharmacological treatment trials of depression representative of patients in routine clinical practice? American Journal of Psychiatry, 159, 469-473.