GM-CSF autoantibodies in pulmonary alveolar proteinosis [6]

New England Journal of Medicine

Volumn 356, Issue 19, 2007, Pages 2001-2002

  Bendtzen, Klaus ^a   Svenson, Morten ^a   Hansen, Morten B ^a  

^a Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR ANTIBODY; IMMUNOGLOBULIN G; UNCLASSIFIED DRUG; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MONOCLONAL ANTIBODY;

ANTIBODY BLOOD LEVEL; HUMAN; LETTER; LUNG ALVEOLUS PROTEINOSIS; NEUTROPHIL; PRIORITY JOURNAL; ADULT RESPIRATORY DISTRESS SYNDROME; DISEASE ASSOCIATION; GAS EXCHANGE; SEPSIS; SURVIVAL; IMMUNOLOGY; NOTE; LEUKOCYTE COUNT; PHYSIOLOGY;

ANTIBODIES, MONOCLONAL; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; RESPIRATORY DISTRESS SYNDROME, ADULT; AUTOANTIBODIES; LEUKOCYTE COUNT; NEUTROPHILS; PULMONARY ALVEOLAR PROTEINOSIS;

EID: 34248329481     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMc070650     Document Type: Letter

References (5)

1. Uchida K, Beck DC, Yamamoto T, et al. GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis. N Engl J Med 2007;356:567-79.
2. Svenson M, Hansen MB, Ross C, et al. Antibody to granulocyte-macrophage colony-stimulating factor is a dominant anti-cytokine activity in human IgG preparations. Blood 1998;91:2054-61.
3. Bendtzen K, Hansen MB, Ross C, Svenson M. High-avidity autoantibodies to cytokines. Immunol Today 1998;19:209-11.
4. Lin FC, Chang GD, Chern MS, Chen YC, Chang SC. Clinical significance of anti-GM-CSF antibodies in idiopathic pulmonary alveolar proteinosis. Thorax 2006;61:528-34.
5. Cho K, Nakata K, Ariga T, et al. Successful treatment of congenital pulmonary alveolar proteinosis with intravenous immunoglobulin G administration. Respirology 2006;11:Suppl:S74-S77.