A review of cis-trans interplay between DNA sequences 5′ to the Gγ- and β-globin genes among Hb F-malta-I heterozygotes/homozygotes and β-thalassemia homozygotes/compound heterozygotes, and the effects of hydroxyurea on the Hb F/F-erythrocyte; the need for large multicenter trials

Hemoglobin

Volumn 31, Issue 2, 2007, Pages 279-288

  Felice, Alex E ^a,b   Borg, Joseph ^a,b   Pizzuto, Monica ^a,b   Cassar, Wilhelmina ^a,b   Galdies, Ruth ^a,b   Wettinger, Stephanie Bezzina ^a,b   Pulis, Svetlana ^a,b   Hunter, Gary J ^b   Caruana, Mary R ^a,b   Farrugia, Mario ^a,b   Scerri, Christian A ^a,b  

^a ST LUKE S HOSPITAL   (Malta)

^b UNIVERSITY OF MALTA   (Malta)

Author keywords

Thalassemia (thal); Hb F; Hb F Malta I; Hb F F erythrocyte; Hydroxyurea (HU)

Indexed keywords

AZACITIDINE; BETA GLOBIN; BUTYRIC ACID; GAMMA GLOBIN; HEMOGLOBIN A; HEMOGLOBIN F; HYDROXYUREA;

BETA THALASSEMIA; BIOSYNTHESIS; BONE MARROW; BONE MARROW SUPPRESSION; CONFERENCE PAPER; CYTOTOXICITY; DNA SEQUENCE; EPIGENETICS; ERYTHROCYTE; GENE EXPRESSION; HEMOGLOBINOPATHY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; INFLAMMATION; LOW DRUG DOSE; NONHUMAN; SICKLE CELL ANEMIA;

BETA-THALASSEMIA; DNA; ERYTHROCYTES; FETAL HEMOGLOBIN; GLOBINS; HETEROZYGOTE DETECTION; HOMOZYGOTE; HUMANS; HYDROXYUREA; MALTA; MUTATION;

EID: 34248224876     PISSN: 03630269     EISSN: 1532432X     Source Type: Journal    
DOI: 10.1080/03630260701297261     Document Type: Conference Paper

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